Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Shingo Iwami"'
Autor:
Tomoki Inagaki, Yoshitaka Sato, Jumpei Ito, Mitsuaki Takaki, Yusuke Okuno, Masahiro Yaguchi, H. M. Abdullah Al Masud, Takahiro Watanabe, Kei Sato, Shingo Iwami, Takayuki Murata, Hiroshi Kimura
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/99509a493399422db57ee62adeb7961f
Autor:
Naotoshi Nakamura, Yurie Kobashi, Kwang Su Kim, Hyeongki Park, Yuta Tani, Yuzo Shimazu, Tianchen Zhao, Yoshitaka Nishikawa, Fumiya Omata, Moe Kawashima, Makoto Yoshida, Toshiki Abe, Yoshika Saito, Yuki Senoo, Saori Nonaka, Morihito Takita, Chika Yamamoto, Takeshi Kawamura, Akira Sugiyama, Aya Nakayama, Yudai Kaneko, Yong Dam Jeong, Daiki Tatematsu, Marwa Akao, Yoshitaka Sato, Shoya Iwanami, Yasuhisa Fujita, Masatoshi Wakui, Kazuyuki Aihara, Tatsuhiko Kodama, Kenji Shibuya, Shingo Iwami, Masaharu Tsubokura
Publikováno v:
PLOS Digital Health, Vol 3, Iss 5, p e0000497 (2024)
As we learned during the COVID-19 pandemic, vaccines are one of the most important tools in infectious disease control. To date, an unprecedentedly large volume of high-quality data on COVID-19 vaccinations have been accumulated. For preparedness in
Externí odkaz:
https://doaj.org/article/abbce656ef634b7abbb9954e4238df34
Autor:
Kosaku Kitagawa, Kwang Su Kim, Masashi Iwamoto, Sanae Hayashi, Hyeongki Park, Takara Nishiyama, Naotoshi Nakamura, Yasuhisa Fujita, Shinji Nakaoka, Kazuyuki Aihara, Alan S Perelson, Lena Allweiss, Maura Dandri, Koichi Watashi, Yasuhito Tanaka, Shingo Iwami
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 3, p e1011238 (2024)
Chronic infection with hepatitis B virus (HBV) is caused by the persistence of closed circular DNA (cccDNA) in the nucleus of infected hepatocytes. Despite available therapeutic anti-HBV agents, eliminating the cccDNA remains challenging. Thus, quant
Externí odkaz:
https://doaj.org/article/106f0b67c3384d5189bfd286b6982a62
Autor:
Junya Sunagawa, Hyeongki Park, Kwang Su Kim, Ryo Komorizono, Sooyoun Choi, Lucia Ramirez Torres, Joohyeon Woo, Yong Dam Jeong, William S. Hart, Robin N. Thompson, Kazuyuki Aihara, Shingo Iwami, Ryo Yamaguchi
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract During the COVID-19 pandemic, human behavior change as a result of nonpharmaceutical interventions such as isolation may have induced directional selection for viral evolution. By combining previously published empirical clinical data analys
Externí odkaz:
https://doaj.org/article/0696756a2820434badd6e3a75807d7aa
Autor:
Yoriyuki Konno, Keiya Uriu, Takayuki Chikata, Toru Takada, Jun-ichi Kurita, Mahoko Takahashi Ueda, Saiful Islam, Benjy Jek Yang Tan, Jumpei Ito, Hirofumi Aso, Ryuichi Kumata, Carolyn Williamson, Shingo Iwami, Masafumi Takiguchi, Yoshifumi Nishimura, Eiji Morita, Yorifumi Satou, So Nakagawa, Yoshio Koyanagi, Kei Sato
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113697- (2024)
Summary: The pandemic HIV-1, HIV-1 group M, emerged from a single spillover event of its ancestral lentivirus from a chimpanzee. During human-to-human spread worldwide, HIV-1 diversified into multiple subtypes. Here, our interdisciplinary investigati
Externí odkaz:
https://doaj.org/article/41d9fc0df08f49a5bbad067261708bcf
Autor:
Teiko Kawahigashi, Shoya Iwanami, Munetomo Takahashi, Joydeep Bhadury, Shingo Iwami, Satoshi Yamazaki
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0292575 (2024)
Hematopoietic stem cells (HSCs) are somatic stem cells that continuously generate lifelong supply of blood cells through a balance of symmetric and asymmetric divisions. It is well established that the HSC pool increases with age. However, not much i
Externí odkaz:
https://doaj.org/article/f0ff85763d7441fe8baa4b24cc990162
Autor:
Taiga Miyazaki, Naoki Hosogaya, Yuri Fukushige, Sachiko Takemori, Shinpei Morimoto, Hiroshi Yamamoto, Makoto Hori, Yoshihito Ozawa, Yuki Shiko, Yosuke Inaba, Tomoya Kurokawa, Hideki Hanaoka, Shoya Iwanami, Kwangsu Kim, Shingo Iwami, Koichi Watashi, Ken Miyazawa, Takashi Umeyama, Satoshi Yamagoe, Yoshitsugu Miyazaki, Takaji Wakita, Makoto Sumiyoshi, Tatsuro Hirayama, Koichi Izumikawa, Katsunori Yanagihara, Hiroshi Mukae, Hitoshi Kawasuji, Yoshihiro Yamamoto, Norihito Tarumoto, Hiroshi Ishii, Hideaki Ohno, Kazuhiro Yatera, Hiroshi Kakeya, Yoshiko Kichikawa, Yasuyuki Kato, Tetsuya Matsumoto, Makoto Saito, Hiroshi Yotsuyanagi, Shigeru Kohno
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Nelfinavir, an orally administered inhibitor of human immunodeficiency virus protease, inhibits the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in vitro. We conducted a randomized controlled trial to evaluate
Externí odkaz:
https://doaj.org/article/0a380e871da94f7abcec22d99a173a53
Autor:
Yong Dam Jeong, Keisuke Ejima, Kwang Su Kim, Woo Joohyeon, Shoya Iwanami, Yasuhisa Fujita, Il Hyo Jung, Kazuyuki Aihara, Kenji Shibuya, Shingo Iwami, Ana I. Bento, Marco Ajelli
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Utilizing viral test results to determine isolation length would minimize both the risk of prematurely ending isolation of infectious patients and the unnecessary individual burden of redundant isolation of noninfectious patients. Here, the authors d
Externí odkaz:
https://doaj.org/article/a4542783991e4f5da1ea434daa9fad0a
Autor:
Keisuke Ejima, Kwang Su Kim, Ana I. Bento, Shoya Iwanami, Yasuhisa Fujita, Kazuyuki Aihara, Kenji Shibuya, Shingo Iwami
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Multiple waves of the COVID-19 epidemic have hit most countries by the end of 2021. Most of those waves are caused by emergence and importation of new variants. To prevent importation of new variants, combination of border control
Externí odkaz:
https://doaj.org/article/804020030fa6473aa342e1539592567c
Autor:
Shiho Torii, Kwang Su Kim, Jun Koseki, Rigel Suzuki, Shoya Iwanami, Yasuhisa Fujita, Yong Dam Jeong, Jumpei Ito, Hiroyuki Asakura, Mami Nagashima, Kenji Sadamasu, Kazuhisa Yoshimura, Genotype to Phenotype Japan (G2P-Japan) Consortium, Kei Sato, Yoshiharu Matsuura, Teppei Shimamura, Shingo Iwami, Takasuke Fukuhara
Publikováno v:
PLoS Pathogens, Vol 19, Iss 3, p e1011231 (2023)
Mutations continue to accumulate within the SARS-CoV-2 genome, and the ongoing epidemic has shown no signs of ending. It is critical to predict problematic mutations that may arise in clinical environments and assess their properties in advance to qu
Externí odkaz:
https://doaj.org/article/d357fa629fa24023ac92f08664dbc0ff