Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Shingo Ishihara"'
Autor:
Alia M. Obeidat, Shingo Ishihara, Jun Li, Natalie S. Adamczyk, Lindsey Lammlin, Lucas Junginger, Tristan Maerz, Richard J. Miller, Rachel E. Miller, Anne-Marie Malfait
Publikováno v:
Frontiers in Neuroanatomy, Vol 18 (2024)
ObjectiveKnee joints are densely innervated by nociceptors. In human knees and rodent models, sprouting of nociceptors has been reported in late-stage osteoarthritis (OA). Here, we sought to describe progressive nociceptor remodeling in early and lat
Externí odkaz:
https://doaj.org/article/c82aa8c802ea4995988701bde3079ef6
Autor:
Alia M. Obeidat, Matthew J. Wood, Natalie S. Adamczyk, Shingo Ishihara, Jun Li, Lai Wang, Dongjun Ren, David A. Bennett, Richard J. Miller, Anne-Marie Malfait, Rachel E. Miller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Non-opioid targets are needed for addressing osteoarthritis pain, which is mechanical in nature and associated with daily activities such as walking and climbing stairs. Piezo2 has been implicated in the development of mechanical pain, but t
Externí odkaz:
https://doaj.org/article/222c434eeda94f0a8702d3c3debb578f
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-15 (2023)
Abstract Background We aimed to explore activation of the Notch signaling pathway in knee-innervating lumbar dorsal root ganglia (DRG) in the course of experimental osteoarthritis (OA) in mice, and its role in knee hyperalgesia. Methods Cultured DRG
Externí odkaz:
https://doaj.org/article/bc10ff1d537c45249f95745226352482
Autor:
Shingo Ishihara, Alia M. Obeidat, David L. Wokosin, Dongjun Ren, Richard J. Miller, Anne-Marie Malfait, Rachel E. Miller
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background C–C chemokine receptor 2 (CCR2) signaling plays a key role in pain associated with experimental murine osteoarthritis (OA) after destabilization of the medial meniscus (DMM). Here, we aimed to assess if CCR2 expressed by intra-a
Externí odkaz:
https://doaj.org/article/f167f2cb2b02483c85aff3a5e8fb88a5
Autor:
Takahiro Kozawa, Kayo Fukuyama, Kizuku Kushimoto, Shingo Ishihara, Junya Kano, Akira Kondo, Makio Naito
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Mechanochemical reactions can be induced in a solution by the collision of balls to produce high-temperature and high-pressure zones, with the reactions occurring through a dissolution–precipitation mechanism due to a change in solubility.
Externí odkaz:
https://doaj.org/article/6dc17029465e4302badab9dda30ed469
Publikováno v:
Energies, Vol 13, Iss 15, p 3836 (2020)
The effect of ventilation bars on the porosity of a sinter bed charged on a sinter machine was investigated. The behavior of the sinter feed was calculated by discrete element method (DEM) simulation. By taking into account the adhesion force, the si
Externí odkaz:
https://doaj.org/article/afc07620150b4555b5f3e8ddf901669a
Publikováno v:
Journal of Fluid Science and Technology, Vol 13, Iss 3, Pp JFST0015-JFST0015 (2018)
We investigate behavior of bouncing and rupturing air bubbles on solid surfaces experimentally. We focus our attention to how the hydrophilicity of the solid surface alters the rupture process. We observe motion of the single bubble of a fixed diamet
Externí odkaz:
https://doaj.org/article/0fe253097cb9463ca06ad67537b5dacc
Publikováno v:
Minerals, Vol 9, Iss 6, p 349 (2019)
This study tested the removal of arsenic from copper ore concentrate via a mechanochemical treatment by planetary ball milling. The harmful components of ore, such as arsenic, are increasing year by year and decreasing the copper grade, therefore the
Externí odkaz:
https://doaj.org/article/408a09fe9fdc4c6c9e69dd71bd93b8b4
Autor:
Shingo ISHIHARA, Junya KANO
Publikováno v:
Journal of the Japan Society of Powder and Powder Metallurgy. 70:197-202
Publikováno v:
Advanced Powder Technology. 32:3717-3724
The crystallinity index of cellulose decrystallized with a vibration rod mill was well correlated with input energy of the vibration rod mill. In order to predict the energy, rod behavior was simulated by discrete element method (DEM). Decrystallizat