Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shingo Bessho"'
Autor:
Kaitlyn Grando, Shingo Bessho, Kayla Harrell, Kathrine Kyrylchuk, Alejandro M. Pantoja, Sophia Olubajo, Francisco J. Albicoro, Andres Klein-Szanto, Çagla Tükel
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Salmonella enterica serovar Typhimurium (STm) causes gastroenteritis and can progress to reactive arthritis (ReA). STm forms biofilms in the gut that secrete the amyloid curli, which we previously demonstrated can trigger autoimmunity in mice. HLA-B2
Externí odkaz:
https://doaj.org/article/bcfce30a541743068d44ceba116779d7
Autor:
Peter Verstraelen, Samuel Van Remoortel, Nouchin De Loose, Rosanne Verboven, Gerardo Garcia-Diaz Barriga, Anne Christmann, Manuela Gries, Shingo Bessho, Jing Li, Carmen Guerra, Çagla Tükel, Sales Ibiza Martinez, Karl-Herbert Schäfer, Jean-Pierre Timmermans, Winnok H. De Vos
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 18, Iss 1, Pp 89-104 (2024)
Background & Aims: Mounting evidence suggests the gastrointestinal microbiome is a determinant of peripheral immunity and central neurodegeneration, but the local disease mechanisms remain unknown. Given its potential relevance for early diagnosis an
Externí odkaz:
https://doaj.org/article/9e6f75de89f84982823a97136cab22fe
Autor:
Shingo Bessho, Kaitlyn C. M. Grando, Kathrine Kyrylchuk, Amanda Miller, Andres J. Klein-Szanto, Wenhan Zhu, Stefania Gallucci, Vincent Tam, Çagla Tükel
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTThe Salmonella biofilm-associated amyloid protein, curli, is a dominant instigator of systemic inflammation and autoimmune responses following Salmonella infection. Systemic curli injections or infection of mice with Salmonella Typhimurium in
Externí odkaz:
https://doaj.org/article/188e20a58d6241adb0debc0e1f35d22a
Autor:
Lauren K Nicastro, Jaime de Anda, Neha Jain, Kaitlyn C M Grando, Amanda L Miller, Shingo Bessho, Stefania Gallucci, Gerard C L Wong, Çagla Tükel
Publikováno v:
PLoS Pathogens, Vol 18, Iss 8, p e1010742 (2022)
Deposition of human amyloids is associated with complex human diseases such as Alzheimer's and Parkinson's. Amyloid proteins are also produced by bacteria. The bacterial amyloid curli, found in the extracellular matrix of both commensal and pathogeni
Externí odkaz:
https://doaj.org/article/56383d3daf1e460f8c4ee0d0b60b724a
Autor:
Amanda L. Miller, Lauren K. Nicastro, Shingo Bessho, Kaitlyn Grando, Aaron P. White, Yi Zhang, Gillian Queisser, Bettina A. Buttaro, Çagla Tükel
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Curli, a major component of the bacterial biofilms in the intestinal tract, activates pattern recognition receptors and triggers joint inflammation after infection with Salmonella enterica serovar Typhimurium. The factors that allow S. Typhi
Externí odkaz:
https://doaj.org/article/376f4c26d0db46758ada73f6bae90904
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The human microbiota is the community of microorganisms that live upon or within their human host. The microbiota consists of various microorganisms including bacteria, fungi, viruses, and archaea; the gut microbiota is comprised mostly of bacteria.
Externí odkaz:
https://doaj.org/article/d24b9d78458e4c828028c981adc777b0