Zobrazeno 1 - 10 of 142 pro vyhledávání: '"Shingo Harada"'
1
Akademický článek
Valence-isomer selective cycloaddition reaction of cycloheptatrienes-norcaradienes
Autor: Shingo Harada, Hiroki Takenaka, Tsubasa Ito, Haruki Kanda, Tetsuhiro Nemoto
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The rapid and precise creation of complex molecules while controlling multiple selectivities is the principal objective in synthetic chemistry. Combining data science and organic synthesis to achieve this goal is an emerging trend, but few e
Externí odkaz: https://doaj.org/article/2ef85328c2404cfea73bc5f1a68c6174
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2
Akademický článek
A novel autophagy inhibitor, bTBT, disturbs autophagosome formation
Autor: Momoka Chiba, Mai Yanagawa, Yurika Oyama, Shingo Harada, Tetsuhiro Nemoto, Akira Matsuura, Eisuke Itakura
Publikováno v: Autophagy Reports, Vol 2, Iss 1 (2023)
Macroautophagy (hereafter, autophagy) is a form of intracellular degradation in which autophagosome formation is systematically coordinated by multiple processes involving numerous autophagy-related gene (ATG) proteins. Autophagy-modulating compounds
Externí odkaz: https://doaj.org/article/c8f10b04c9c349e2a307d04cec2c8332
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3
Akademický článek
Debranching thoracic endovascular aortic repair for distal aortic arch aneurysm in elderly patients aged over 75 years old
Autor: Suguru Shiraya, Yoshinobu Nakamura, Shingo Harada, Yuichiro Kishimoto, Takeshi Onohara, Yuki Otsuki, Tomohiro Kurashiki, Hiromu Horie, Motonobu Nishimura
Publikováno v: Journal of Cardiothoracic Surgery, Vol 15, Iss 1, Pp 1-7 (2020)
Abstract Background We examined the outcome of debranching thoracic endovascular aortic repair (d-TEVAR) without sternotomy for distal aortic arch aneurysm in patients aged ≥75 years. Methods Patients who underwent d-TEVAR or TAR for aortic arch an
Externí odkaz: https://doaj.org/article/05577095516a4295a61a29ff0ff9043a
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7
Synthetic Study of Dragmacidin E: Enantioselective Construction of the Seven-Membered Ring-Fused Indole Skeleton with Contiguous Stereocenters
Autor: Dongil Choi, Noa Takahashi, Haruka Maruoka, Shingo Harada, Alina Nastke, Harald Gröger, Tetsuhiro Nemoto
We developed an enantioselective synthetic method of constructing a seven-membered ring-fused indole skeleton with contiguous stereocenters for the synthesis of dragmacidin E. Introduction of chirality at the benzylic position was achieved by Ir-cata
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f7f0a95a23782a5451134cfdda44566
https://doi.org/10.1021/acs.joc.2c02216
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8
Total Synthesis of (+)-Shearilicine
Autor: Daria E. Kim, Yingchuan Zhu, Shingo Harada, Isaiah Aguilar, Abbigayle E. Cuomo, Minghao Wang, Timothy R. Newhouse
Herein we report the first total synthesis of the indole diterpenoid natural product shearilicine by an 11-step sequence. This synthesis features the development of a generalizable core precursor to the highly oxidized subclass of indole diterpenoids
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6acfac034427c2b4d67b449430cbcf
https://doi.org/10.26434/chemrxiv-2022-kjz7v
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10
Site-Selective and Chemoselective C–H Functionalization for the Synthesis of Spiroaminals via a Silver-Catalyzed Nitrene Transfer Reaction
Autor: Shingo Harada, Tetsuhiro Nemoto, Masato Kono, Mayu Kobayashi
Publikováno v: ACS Catalysis. 10:13296-13304
Although intense research over the last 2 decades revealed a diverse proficiency of nitrene species in chemistry disciplines, control of the selectivity in the reaction manifold has remained a chal...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7923ca59fff7b4afba877bac12d19f98
https://doi.org/10.1021/acscatal.0c04057
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