Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shing-Hung Mak"'
Autor:
Wei-Hui Hu, Shing-Hung Mak, Zhong-Yu Zheng, Ying-Jie Xia, Miranda Li Xu, Ran Duan, Tina Ting-Xia Dong, Shao-Ping Li, Chang-Sen Zhan, Xiao-Hui Shang, Karl Wah-Keung Tsim
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
BackgroundShexiang Baoxin Pill (SBP), a formulated traditional Chinese medicine (TCM), has been widely used to treat cardiovascular diseases for years. This herbal mixture has been shown to promote differentiation of cultured neuronal cells. Here, we
Externí odkaz:
https://doaj.org/article/0f60fca9017f46b387e1eddeabeeef40
Autor:
Cheng-you Zheng, Bao-jian Guo, Wei Cai, Wei Cui, Shing-hung Mak, Yu-qiang Wang, Simon Ming-yuen Lee, Yi-fan Han, Zai-jun Zhang
Publikováno v:
Neural Regeneration Research, Vol 11, Iss 8, Pp 1339-1346 (2016)
Rasagiline, a monoamine oxidase-B inhibitor, and bis(propyl)-cognitin (B3C), a novel dimer are reported to be neuroprotective. Herein, the synergistical neuroprotection produced by rasagiline and B3C was investigated in 1-methyl-4-phenyl-1,2,3,6-tetr
Externí odkaz:
https://doaj.org/article/d4fc58dd84c34d20828aee15c6475cfc
Autor:
Tina T. X. Dong, Tracy Chen-Xi Xia, Marvin Shing-Hung Mak, Karl Wah Keung Tsim, Kenneth Kin Leung Kwan, Brody Zhong-Yu Zheng, Alex Xiong Gao, Jian Xiao
Publikováno v:
Food & Function. 12:11515-11525
Luteolin, a flavonoid in fruits and vegetables, has neurotrophic functions without a well-characterized mechanism. Here, we hypothesize a direct interaction of luteolin with nerve growth factor (NGF); as such, the functionality of the NGF could be po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d97c35d6c30d8ee2f7699d62ecc669d8
https://doi.org/10.1039/d1fo01096d
https://doi.org/10.1039/d1fo01096d
Autor:
Alex Xiong Gao, Tracy Chen-Xi Xia, Marvin Shing-Hung Mak, Kevin Yue Zhu, Tina Ting-Xia Dong, Karl Wah-Keung Tsim
Publikováno v:
Evidence-Based Complementary and Alternative Medicine.
Medicinal food homology is referring to a group of food itself being considered as herbal medicine without a boundary of usage. Under the guidance of this food/medicine principle, the current study aims to develop anti-depressant from this food/medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b58d4eda1cfe052f8f2c7cfe0457cf9
Autor:
Yifan Han, Liangmiao Wu, Ling Zha, Shing Hung Mak, Ning Li, Xifei Yang, Zaijun Zhang, Yuqiang Wang, Maggie Pui Man Hoi, Gaoxiao Zhang, Xinhua Zhou, Yewei Sun, Zhiyang Su, Yiwan Cao
Publikováno v:
Aging Cell
Alzheimer's disease (AD) is a leading cause of dementia in elderly individuals and therapeutic options for AD are very limited. Over‐activation of N‐methyl‐D‐aspartate (NMDA) receptors, amyloid β (Aβ) aggregation, a decrease in cerebral blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd901e15b2def0be0a40d8ec9054bbe7
https://pubmed.ncbi.nlm.nih.gov/33955647
https://pubmed.ncbi.nlm.nih.gov/33955647
Autor:
Dongsheng Zhou, Yiying Zhou, Zhenquan Xuan, Paul R. Carlier, Haibo Jin, Wei Cui, Sicheng Yan, Shengquan Hu, Karl Wah Keung Tsim, Yifan Han, Yanfei Xie, Hui Zhang, Xingmei Gu, Marvin Shing-Hung Mak
Background Alzheimer’s disease (AD) is a neurodegenerative disorder with multiple pathological features. Therefore, multi-target-directed ligands (MTDLs) strategy has been developed to combat this disease. We have previously designed and synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b114556c414e3d1cd101a72917a5bb6f
https://doi.org/10.21203/rs.3.rs-236543/v1
https://doi.org/10.21203/rs.3.rs-236543/v1
Autor:
Xiong Gao, Alex, Xia, Tracy Chen-Xi, Shing-Hung Mak, Marvin, Kin-Leung Kwan, Kenneth, Zhong-Yu Zheng, Brody, Xiao, Jian, Dong, Tina Ting-Xia, Tsim, Karl Wah-Keung
Publikováno v:
Food & Function; 11/21/2021, Vol. 12 Issue 22, p11515-11525, 11p
Autor:
Yuan Ping Pang, Yifan Han, Ming Yuen Lee, Wei Cui, Rui Wang, Yuanjia Hu, Shing Hung Mak, Sheng Quan Hu, Gang Li
Publikováno v:
CNS Neuroscience & Therapeutics. 21:953-961
Summary Aims Fibrillar aggregates of β-amyloid protein (Aβ) are the main constituent of senile plaques and considered to be one of the causative events in the pathogenesis of Alzheimer's disease (AD). Compounds that could inhibit Aβ fibrils format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be177746deb397fe869711d605d09a00
https://doi.org/10.1111/cns.12472
https://doi.org/10.1111/cns.12472
Autor:
Adrian Weber, Shing Hung Mak, Francis Berenbaum, Yongping Zheng, Chunyi Wen, Yifan Han, Jérémie Sellam
Publikováno v:
Medicine. 98:e14355
OBJECTIVE To investigate the possible association between osteoarthritis (OA) and the risk of dementia. METHODS Cohort, case-control, and cross-sectional studies were obtained from wide literature search up to 20 April 2018 from following electronic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f5627163ddd04a7e8c37c752591df7
https://doi.org/10.1097/md.0000000000014355
https://doi.org/10.1097/md.0000000000014355
Autor:
Karl Wah Keung Tsim, Yuanjia Hu, Wei Cui, Chung Lit Choi, Sheng Quan Hu, Yuan Ping Pang, Yifan Han, Gang Li, Shing Hung Mak
Summary Aims Neurodegenerative disorders are caused by progressive neuronal loss in the brain, and hence, compounds that could promote neuritogenesis may have therapeutic values. In this study, the effects of bis(heptyl)-cognitin (B7C), a multifuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e42e895ccbae96e7fb486a8c7c29cfa
https://europepmc.org/articles/PMC6495446/
https://europepmc.org/articles/PMC6495446/