Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shing-Hing Lau"'
Autor:
Steven V. Ley, Shing-Hing Lau, Jian-Siang Poh, José Augusto Forni, Julio Cezar Pastre, Claudio Battilocchio
Publikováno v:
Synlett. 29:825-829
A new three-component coupling protocol for preparation of functionalized indolines, with a high degree of diastereoselectivity, has been developed. The protocol is based on the in situ homologation of vinyl boronic acids to allylboronic acids, using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f67db07ae36dea51385e71b2afca00fd
https://doi.org/10.1055/s-0036-1589164
https://doi.org/10.1055/s-0036-1589164
Autor:
Shing-Hing Lau
Publikováno v:
Organic Syntheses. 94:34-45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00e3d4bedc141f8f263320846b4dc74b
https://doi.org/10.15227/orgsyn.094.0034
https://doi.org/10.15227/orgsyn.094.0034
Autor:
Steven V. Ley, Jian-Siang Poh, Duc N. Tran, Shing-Hing Lau, Iain G. Dykes, Claudio Battilocchio
Publikováno v:
Chemical Science. 7:6803-6807
Here we report the in situ generation of transient allylic boronic species, by reacting TMSCHN2 and E-vinyl boronic acids, followed by their subsequent trapping with aldehydes as electrophiles to yield homoallylic alcohols. This metal-free reaction w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4052b26bb671274a638e42d9ad55a9
https://doi.org/10.1039/c6sc02581a
https://doi.org/10.1039/c6sc02581a
A procedure that yields pyrazinamide as a fine white powder is presented. A glass column reactor is used containing Celite and manganese dioxide and is mounted vertically in a heating jacket. Following the procedure are notes on the instruments and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64edd1c5a09f442a803680cf22b0d8ab
https://www.repository.cam.ac.uk/handle/1810/262538
https://www.repository.cam.ac.uk/handle/1810/262538
Autor:
Elena M. Barreiro, Eric Tan, Silvia Díez-González, Shing-Hing Lau, Alvaro Sanz-Vidal, Tom D. Sheppard
Publikováno v:
European Journal of Organic Chemistry. 2015:7544-7549
The activity of HBF4 (aqueous solution) as a catalyst in propargylation reactions is presented. Diverse types of nucleophiles were employed in order to form new C–O, C–N and C–C bonds in technical acetone and in air. Good to excellent yields an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45398ff08d990408e43b078a91637600
https://doi.org/10.1002/ejoc.201501249
https://doi.org/10.1002/ejoc.201501249
Autor:
Penn Gerhard, Shing-Hing Lau, Berthold Schenkel, Benjamin Martin, Samuel L. Bourne, Steven V. Ley
Publikováno v:
Organic Letters. 17:5436-5439
An efficient preparation of a precursor to the neprilysin inhibitor sacubitril is described. The convergent synthesis features a diastereoselective Reformatsky-type carbethoxyallylation and a rhodium-catalyzed stereoselective hydrogenation for instal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::772f93d94806cc19a61707dd428d2f88
https://doi.org/10.1021/acs.orglett.5b02806
https://doi.org/10.1021/acs.orglett.5b02806
Autor:
Janna Ehlert, Steven V. Ley, Mikhail A. Kabeshov, Claudio Battilocchio, Shing-Hing Lau, Arthur R. Lit, Claudio Bomio
Publikováno v:
Chemical Science
By means of computational and experimental mechanistic studies the fundamental role of boroxines in the reaction between diazo compounds and boronic acids was elucidated.
By means of computational and experimental mechanistic studies the fundame
By means of computational and experimental mechanistic studies the fundame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::038c76c0f1228c36ba0ecdd44afb24bb
https://pubmed.ncbi.nlm.nih.gov/29619197
https://pubmed.ncbi.nlm.nih.gov/29619197
Autor:
Shing-Hing Lau, Silvia Díez-González, Eric Tan, Alvaro Sanz-Vidal, Elena M. Barreiro, Tom D. Sheppard
Publikováno v:
ChemInform. 47
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99f4e9ca5e572d88351bbafcf7f8035c
https://doi.org/10.1002/chin.201614063
https://doi.org/10.1002/chin.201614063
Autor:
Shing-Hing, Lau, Alicia, Galván, Rohan R, Merchant, Claudio, Battilocchio, José A, Souto, Malcolm B, Berry, Steven V, Ley
Publikováno v:
Organic letters. 17(13)
An efficient preparation of the antimalarial drug candidate OZ439, which was obtained by integrating a machine-assisted approach with batch processes, is reported. This approach allows a rapid and cost-effective production of the key intermediates th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c47d447e7704a9c7f46f2db71b950832
https://pubmed.ncbi.nlm.nih.gov/26079282
https://pubmed.ncbi.nlm.nih.gov/26079282
Autor:
Forni, José A., Shing-Hing Lau, Jian-Siang Poh, Battilocchio, Claudio, Ley, Steven V., Pastre, Julio C.
Publikováno v:
Synlett; 2018, Vol. 29 Issue 6, p825-829, 5p