Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Shing Yan Chiu"'
Autor:
Aditya Rayasam, Julie A. Kijak, Lee Kissel, Yun Hwa Choi, Taehee Kim, Martin Hsu, Dinesh Joshi, Collin J. Laaker, Peter Cismaru, Anders Lindstedt, Krisztian Kovacs, Raghu Vemuganti, Shing Yan Chiu, Thanthrige Thiunuwan Priyathilaka, Matyas Sandor, Zsuzsanna Fabry
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-15 (2022)
Abstract Background Ischemic stroke is a leading cause of mortality worldwide, largely due to the inflammatory response to brain ischemia during post-stroke reperfusion. Despite ongoing intensive research, there have not been any clinically approved
Externí odkaz:
https://doaj.org/article/e710bc3210a84704b042530e01331994
Autor:
Guorui Huang, Dawiyat Massoudi, Alison M. Muir, Dinesh C. Joshi, Chuan-Li Zhang, Shing Yan Chiu, Daniel S. Greenspan
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 923-934 (2017)
Regulated inter-mitochondrial fusion/fission is essential for maintaining optimal mitochondrial respiration and control of apoptosis and autophagy. In mammals, mitochondrial fusion is controlled by outer membrane GTPases MFN1 and MFN2 and by inner me
Externí odkaz:
https://doaj.org/article/1fb90bd1e43b4e8187c08d8191e4b2e4
Autor:
Dinesh C. Joshi, Chuan-Li Zhang, Lavanya Babujee, Jason D. Vevea, Benjamin K. August, Zu-Hang Sheng, Edwin R. Chapman, Timothy M. Gomez, Shing Yan Chiu
Publikováno v:
Cell Reports, Vol 29, Iss 3, Pp 685-696.e5 (2019)
Summary: Syntaphilin (SNPH) is a major mitochondrial anchoring protein targeted to axons and excluded from dendrites. In this study, we provide in vivo evidence that this spatial specificity is lost in Shiverer (Shi) mice, a model for progressive mul
Externí odkaz:
https://doaj.org/article/237993e2ba8e495b9b0742079b56acc3
Autor:
Dinesh C. Joshi, Chuan-Li Zhang, Deepali Mathur, Alex Li, Gaurav Kaushik, Zu-Hang Sheng, Shing-Yan Chiu
Publikováno v:
J Neurosci
The mitochondrial anchor syntaphilin (SNPH) is a key mitochondrial protein normally expressed in axons to maintain neuronal health by positioning mitochondria along axons for metabolic needs. However, in 2019 we discovered a novel form of excitotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa5eeaebdbecf65a609d74513fa41eb
https://europepmc.org/articles/PMC9512578/
https://europepmc.org/articles/PMC9512578/
Autor:
Dinesh C. Joshi, Krisztian Kovacs, Collin Laaker, Thanthrige Thiunuwan Priyathilaka, Shing Yan Chiu, TaeHee Kim, Peter Cismaru, Julie A. Kijak, Lee Kissel, Raghu Vemuganti, Matyas Sandor, Martin Hsu, Anders Lindstedt, Zsuzsanna Fabry, Aditya Rayasam
Background: Ischemic stroke is a leading cause of mortality worldwide, largely due to the inflammatory response to brain ischemia during post-stroke reperfusion. Despite ongoing intensive research, there have not been any clinically approved drugs ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::709cb24ba18707a6d07bb2b2b47ab201
https://doi.org/10.21203/rs.3.rs-1032310/v1
https://doi.org/10.21203/rs.3.rs-1032310/v1
Autor:
Joshi, Dinesh C., Chuan-Li Zhang, Mathur, Deepali, Li, Alex, Kaushik, Gaurav, Zu-Hang Sheng, Shing-Yan Chiu
Publikováno v:
Journal of Neuroscience; 9/21/2022, Vol. 42 Issue 38, p7318-7329, 12p
Autor:
Chuan-Li Zhang, Dawiyat Massoudi, Dinesh C. Joshi, Alison M. Muir, Shing Yan Chiu, Guorui Huang, Daniel S. Greenspan
Publikováno v:
Cell Reports, Vol 20, Iss 4, Pp 923-934 (2017)
Regulated inter-mitochondrial fusion/fission is essential for maintaining optimal mitochondrial respiration and control of apoptosis and autophagy. In mammals, mitochondrial fusion is controlled by outer membrane GTPases MFN1 and MFN2 and by inner me
Autor:
Hasan Mukhtar, Rahul K. Lall, Dinesh C. Joshi, Anant Singh, Mario Sechi, Saheed O. Afolabi, Shing Yan Chiu, Deeba N. Syed
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports
Scientific Reports
The anti-proliferative activity of dietary flavonoid fisetin has been validated in various cancer models. Establishing its precise mechanism of action has proved somewhat challenging given the multiplicity of its targets. We demonstrated that YB-1 pr
Autor:
Chuan-Li Zhang, Timothy M. Gomez, Lavanya Babujee, Jason D. Vevea, Dinesh C. Joshi, Shing Yan Chiu, Benjamin K. August, Edwin R. Chapman, Zu-Hang Sheng
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 3, Pp 685-696.e5 (2019)
Cell Reports, Vol 29, Iss 3, Pp 685-696.e5 (2019)
SUMMARY Syntaphilin (SNPH) is a major mitochondrial anchoring protein targeted to axons and excluded from dendrites. In this study, we provide in vivo evidence that this spatial specificity is lost in Shiverer (Shi) mice, a model for progressive mult
Autor:
Hisashi Fujioka, Dinesh C. Joshi, Panjamaporn Sangwung, Xudong Liao, Jose Torio, Jiyun Zhu, Mukesh K. Jain, David R Sweet, Lan Wang, Shing Yan Chiu, Qiaoyuan Li, Colleen M. Croniger, Yuan Lu, Paishiun Hsieh
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Brown adipose tissue (BAT) is a specialized thermogenic organ in mammals. The ability of BAT mitochondria to generate heat in response to cold-challenge to maintain core body temperature is essential for organismal survival. While cold activated BAT