Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shing‐Hu Cheung"'
Autor:
Xi Yuan, Zhiyu Tang, Rong Du, Zhan Yao, Shing‐Hu Cheung, Xinwen Zhang, Jing Wei, Yuan Zhao, Yunguang Du, Ye Liu, Xiaoxia Hu, Wenfeng Gong, Yong Liu, Yajuan Gao, Zhiyue Huang, Zongfu Cao, Min Wei, Changyou Zhou, Lai Wang, Neal Rosen, Paul D. Smith, Lusong Luo
Publikováno v:
Molecular Oncology, Vol 14, Iss 8, Pp 1833-1849 (2020)
The mutation of K‐RAS represents one of the most frequent genetic alterations in cancer. Targeting of downstream effectors of RAS, including of MEK and ERK, has limited clinical success in cancer patients with K‐RAS mutations. The reduced sensiti
Externí odkaz:
https://doaj.org/article/3c9d127250f544f0b8e196531da074da
Autor:
Lusong Luo, Lai Wang, Changyou Zhou, Min Wei, David Sutton, Shuangxi Li, Lianhai Zhang, Jiafu Ji, Shaohui Wang, Shengjian Li, Rui Hao, Ye Liu, Yajuan Gao, Yong Liu, Wenfeng Gong, Xiaoxia Hu, Yunguang Du, Yi Zhang, Hao Peng, Yingcai Feng, Yuan Zhao, Jing Wei, Guoliang Zhang, Shing-Hu Cheung, Rong Du, Xi Yuan, Zhiyu Tang
Supplementary Tables S1-S6 and Supplementary Figures S1-S2. Table S1: Data collection and refinement statistics, related to Figure 1B; Table S2: Summary of cell line related information; Table S3: BGB-283 is a reversible B-RAF inhibitor; Table S4. Ki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e1162ae1e5106b32e559ede087e8b9
https://doi.org/10.1158/1535-7163.22505985
https://doi.org/10.1158/1535-7163.22505985
Supplementary Methods, Figures 1-9 from Modulation of Gene Expression and Tumor Cell Growth by Redox Modification of STAT3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896b3d791f824ae65a24d27c8a4aa327
https://doi.org/10.1158/0008-5472.22384877.v1
https://doi.org/10.1158/0008-5472.22384877.v1
Autor:
Zhan Yao, Rong Du, Changyou Zhou, Neal Rosen, Xi Yuan, Zongfu Cao, Yunguang Du, Jing Wei, Min Wei, Lai Wang, Zhiyu Tang, Wenfeng Gong, Yong Liu, Shing-Hu Cheung, Xinwen Zhang, Yajuan Gao, Ye Liu, Paul D. Smith, Lusong Luo, Xiaoxia Hu, Yuan Zhao, Zhiyue Huang
Publikováno v:
Molecular Oncology, Vol 14, Iss 8, Pp 1833-1849 (2020)
Molecular Oncology
Molecular Oncology
The mutation of K‐RAS represents one of the most frequent genetic alterations in cancer. Targeting of downstream effectors of RAS, including of MEK and ERK, has limited clinical success in cancer patients with K‐RAS mutations. The reduced sensiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7feb700face8f95efcfd1797f8b445
https://doaj.org/article/3c9d127250f544f0b8e196531da074da
https://doaj.org/article/3c9d127250f544f0b8e196531da074da
Autor:
Martin Bechem, Volker Laux, Bo Tang, Chunyan Luo, Qiuyun Chen, Kirsten Leineweber, Elisabeth Pook, Qing Kenneth Wang, Shing Hu Cheung, Weiyi Zhang, Jing Shan Hu, Sisi Li
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:2319-2332
Low androgen levels are associated with an increased risk of coronary artery disease (CAD), thrombosis and myocardial infarction (MI), suggesting that androgen has a protective role. However, little is known about the underlying molecular mechanism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595c251fa0f4ed00d0526fe3af531246
https://doi.org/10.1016/j.bbadis.2017.06.015
https://doi.org/10.1016/j.bbadis.2017.06.015
Autor:
Wortmann, Lars, Bräuer, Nico, Holton, Simon J., Irlbacher, Horst, Weiske, Jörg, Lechner, Christian, Meier, Robin, Karén, Jakob, Siöberg, Catrine Berthold, Pütter, Vera, Christ, Clara D., Laak, Antonius ter, Lienau, Philip, Lesche, Ralf, Nicke, Barbara, Shing-Hu Cheung, Bauser, Marcus, Haegebarth, Andrea, von Nussbaum, Franz, Mumberg, Dominik
Publikováno v:
Journal of Medicinal Chemistry; 11/11/2021, Vol. 64 Issue 21, p15883-15911, 29p
Autor:
Xinwen Zhang, Min Wei, Badreddin Edris, Xi Yuan, Mary Lou Smith, Lai Wang, Rong Du, Changyou Zhou, Neal Rosen, Zhan Yao, Claire N. Thant, Lusong Luo, Todd Shearer, Shing-Hu Cheung
Publikováno v:
Cancer Research. 80:6415-6415
K-RAS mutation represents one of the most frequent genetic alterations in cancers. Monotherapy approaches targeting RAS downstream effectors such as MEK and ERK have had limited clinical success in patients with K-RAS-mutated cancers. The reduced sen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32bad8b34499531246ce879a8d6c6d41
https://doi.org/10.1158/1538-7445.am2020-6415
https://doi.org/10.1158/1538-7445.am2020-6415
Autor:
Fan Wang, Elisabeth Pook, Shing-Hu Cheung, Xiang Ren, Yinhong Song, Chengqi Xu, Bo Tang, Jing-Shan Hu, Stephen Archacki, Xin Tu, Weiyi Zhang, Qiuyun Chen, Weifeng Huang, Qing Kenneth Wang, Tie Ke, Volker Laux, Martin Bechem, Kirsten Leineweber, Chunyan Luo, Jian Yang
Publikováno v:
Gene. 753:144805
Genomic variants in both ADTRP and TFPI genes are associated with risk of coronary artery disease (CAD). ADTRP regulates TFPI expression and endothelial cell functions involved in the initiation of atherosclerotic CAD. ADTRP also specifies primitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07814fd4da75b6aa9c943632b8d48395
https://doi.org/10.1016/j.gene.2020.144805
https://doi.org/10.1016/j.gene.2020.144805
Autor:
Rui Hao, Rong Du, Hao Peng, Xi Yuan, Wenfeng Gong, Changyou Zhou, Wang Shaohui, Ye Liu, Shuangxi Li, Min Wei, Lai Wang, Yajuan Gao, Zhiyu Tang, Yingcai Feng, Shengjian Li, Guoliang Zhang, David Sutton, Jing Wei, Yong Liu, Yunguang Du, Xiaoxia Hu, Lusong Luo, Yuan Zhao, Jiafu Ji, Shing Hu Cheung, Lianhai Zhang, Yi Zhang
Publikováno v:
Molecular Cancer Therapeutics. 14:2187-2197
Oncogenic BRAF, which drives cell transformation and proliferation, has been detected in approximately 50% of human malignant melanomas and 5% to 15% of colorectal cancers. Despite the remarkable clinical activities achieved by vemurafenib and dabraf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7a0c639ef6a8e5ef1814706d7e74c0
https://doi.org/10.1158/1535-7163.mct-15-0262
https://doi.org/10.1158/1535-7163.mct-15-0262
Autor:
Jing-Shan Hu, Sisi Li, Weiyi Zhang, Kirsten Leineweber, Martin Bechem, Chunyan Luo, Elisabeth Pook, Bo Tang, Qiuyun Chen, Volker Laux, Qing Wang, Shing-Hu Cheung
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Low androgen levels are associated with an increased risk of coronary artery disease (CAD), thrombosis and myocardial infarction (MI), suggesting that androgen has a protective role. However, little is known about the underlying molecular mechanism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::618bb22f69c56d0bf8597fee345ecaaf
https://doi.org/10.1161/atvb.37.suppl_1.409
https://doi.org/10.1161/atvb.37.suppl_1.409