Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Shing, Kam"'
Autor:
Charles Shing Kam, Daniel Wai-Hung Ho, Vanessa Sheung-In Ming, Lu Tian, Karen Man-Fong Sze, Vanilla Xin Zhang, Yu-Man Tsui, Abdullah Husain, Joyce Man-Fong Lee, Carmen Chak-Lui Wong, Albert Chi-Yan Chan, Tan-To Cheung, Lo-Kong Chan, Irene Oi-Lin Ng
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 6, Pp 1325-1350 (2023)
Background & Aims: Metabolic reprogramming is recognized as a cancer hallmark intimately linked to tumor hypoxia, which supports rapid tumor growth and mitigates the consequential oxidative stress. Phosphofructokinase-fructose bisphosphatase (PFKFB)
Externí odkaz:
https://doaj.org/article/4caaf380883542f299e658fda3245384
Publikováno v:
Hepatology. 75:1038-1049
In association with the pandemic spreading of obesity and metabolic syndrome, the prevalence of NAFLD-related HCC is increasing almost exponentially. In recent years, many of the underlining multifactorial causes of NAFLD have been identified, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35059096c7855772a5784b4cb13b1e4d
https://doi.org/10.1002/hep.32336
https://doi.org/10.1002/hep.32336
Autor:
Vanessa Sheung-In Ming, Lu Tian, Lo-Kong Chan, Vanilla Xin Zhang, Luqing Zhao, Irene Oi-Lin Ng, Karen Man-Fong Sze, Daniel W.H. Ho, Charles Shing Kam, Xia Wang, Tan To Cheung
Publikováno v:
Hepatology (Baltimore, Md.). 76(1)
Ras-like (Ral) small guanosine triphosphatases (GTPases), RalA and RalB, are proto-oncogenes directly downstream of Ras and cycle between the active guanosine triphosphate-bound and inactive guanosine diphosphate-bound forms. RalGTPase-activating pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f572b7e48d658b3090d4f3b1a07ca9ec
https://pubmed.ncbi.nlm.nih.gov/34767674
https://pubmed.ncbi.nlm.nih.gov/34767674
Publikováno v:
Cancers, Vol 13, Iss 5250, p 5250 (2021)
Cancers
Cancers
Simple Summary Liver cancer is one of the most frequently occurring cancer types and one of the leading causes of cancer-related mortality globally. Despite of its constantly growing incidence, the efficacy of the current therapeutic interventions is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c5332d84f28ba838a9c47d5d13c530
https://www.mdpi.com/2072-6694/13/20/5250
https://www.mdpi.com/2072-6694/13/20/5250
Autor:
Ido Yofe, Shir Shlomi-Loubaton, Yana Davidov, Oranit Cohen-Ezra, Oren Barboy, Diego Jaitin, David Goitein, Dominik Pfister, Aleksandra Deczkowska, Amir Giladi, Merav Cohen, Chamutal Gur, Mathias Heikenwalder, Michael Safran, Susanne Roth, Sandrine Henri, Assaf Weiner, Eylon Lahat, Ziv Ben-Ari, Gil Ben Yakov, Bernard Malissen, Mengjie Qiu, Ido Amit, Shing Kam, Hila Hermon, Yousuf Suhail, Mariya Likhter, Achim Weber, Eran Elinav, Eyal David, Pierluigi Ramadori
Publikováno v:
Nature Medicine
Nature Medicine, Nature Publishing Group, 2021, ⟨10.1038/s41591-021-01344-3⟩
Nature Medicine, 2021, ⟨10.1038/s41591-021-01344-3⟩
Nature Medicine, Nature Publishing Group, 2021, ⟨10.1038/s41591-021-01344-3⟩
Nature Medicine, 2021, ⟨10.1038/s41591-021-01344-3⟩
International audience; Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are prevalent liver conditions that underlie the development of life-threatening cirrhosis, liver failure and liver cancer. Chronic necro-infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a635b1f210791c3fa08beb091c7565
https://hal.archives-ouvertes.fr/hal-03234079
https://hal.archives-ouvertes.fr/hal-03234079
Autor:
Aleksandra, Deczkowska, Eyal, David, Pierluigi, Ramadori, Dominik, Pfister, Michal, Safran, Baoguo, Li, Amir, Giladi, Diego Adhemar, Jaitin, Oren, Barboy, Merav, Cohen, Ido, Yofe, Chamutal, Gur, Shir, Shlomi-Loubaton, Sandrine, Henri, Yousuf, Suhail, Mengjie, Qiu, Shing, Kam, Hila, Hermon, Eylon, Lahat, Gil, Ben Yakov, Oranit, Cohen-Ezra, Yana, Davidov, Mariya, Likhter, David, Goitein, Susanne, Roth, Achim, Weber, Bernard, Malissen, Assaf, Weiner, Ziv, Ben-Ari, Mathias, Heikenwälder, Eran, Elinav, Ido, Amit
Publikováno v:
Nature medicine. 27(6)
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are prevalent liver conditions that underlie the development of life-threatening cirrhosis, liver failure and liver cancer. Chronic necro-inflammation is a critical fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9daa5f15ccd8c4c0a2e35415b380125e
https://pubmed.ncbi.nlm.nih.gov/35022579
https://pubmed.ncbi.nlm.nih.gov/35022579
Autor:
Tan To Cheung, Elaine Tin Yan Cheung, Victor Wai-Lun Tang, Lo Kong Chan, Kenneth S. H. Chok, Albert C. Y. Chan, Irene Lai Oi Lo, Chun-Ming Wong, Charles Shing Kam, Terence Kin Wah Lee, Elley Yung Tuen Chiu, Daniel W.H. Ho, Chung Ngai Tang, Irene Oi-Lin Ng, Derek Tsz-Wai Yau, Carmen Chak-Lui Wong
Publikováno v:
Journal of hepatology. 74(2)
Background & Aims Mutational profiling of patient tumors has suggested that hepatocellular carcinoma (HCC) development is mainly driven by loss-of-function mutations in tumor suppressor genes. p90 ribosomal S6 kinase 2 (RSK2) functions as a direct do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b601f636ca3fd3565aafdb41a8dcfeae
https://pubmed.ncbi.nlm.nih.gov/32918955
https://pubmed.ncbi.nlm.nih.gov/32918955
Autor:
Hung, Shing-kam, Phoebe.
Publikováno v:
Click to view the E-thesis via HKUTO.
Thesis (M.A.)--University of Hong Kong, 2008.
Includes bibliographical references (p. 67-69)
Includes bibliographical references (p. 67-69)
Externí odkaz:
http://sunzi.lib.hku.hk/hkuto/record/B40717161