Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Shine-Gwo Shiah"'
Autor:
Chieh Huo, Ying‐Yu Kuo, Ching‐Yu Lin, Shine‐Gwo Shiah, Chia‐Yang Li, Shu‐Pin Huang, Jen‐Kun Chen, Wen‐Ching Wang, Hsing‐Jien Kung, Chih‐Pin Chuu
Publikováno v:
Cancer Medicine, Vol 13, Iss 16, Pp n/a-n/a (2024)
Abstract Background Prostate cancer (PCa) patients with elevated level of androgen receptor (AR) correlate with higher metastatic incidence. Protein expression of AR and its target gene prostate‐specific antigen (PSA) are elevated in metastatic pro
Externí odkaz:
https://doaj.org/article/39ea7ea40a3a452fa6a80b7de7df3a9c
Autor:
Chia-Yun Huang, Sung-Tau Chou, Yuan-Ming Hsu, Wan-Ju Chao, Guan-Hsun Wu, Jenn-Ren Hsiao, Horng-Dar Wang, Shine-Gwo Shiah
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7576 (2024)
Exosomal microRNAs (miRNAs) from cancer cells play a key role in mediating the oral squamous cell carcinoma (OSCC) microenvironment. The objective of this study was to investigate how the long non-coding RNA (lncRNA) MEG3 affects OSCC angiogenesis th
Externí odkaz:
https://doaj.org/article/d4017e117d9841289aecc2074845634e
Autor:
Hung-Da Chou, Shine-Gwo Shiah, Lan-Hsin Chuang, Wei-Chi Wu, Yih-Shiou Hwang, Kuan-Jen Chen, Eugene Yu-Chuan Kang, Ling Yeung, Chung-Yi Nien, Chi-Chun Lai
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 24, p 17188 (2023)
Müller cells play a critical role in the closure of macular holes, and their proliferation and migration are facilitated by the internal limiting membrane (ILM). Despite the importance of this process, the underlying molecular mechanism remains unde
Externí odkaz:
https://doaj.org/article/2eece13c5b424e46bd8814e490eb680a
Autor:
Hsuan-Yu Peng, Jenn-Ren Hsiao, Sung-Tau Chou, Yuan-Ming Hsu, Guan-Hsun Wu, Yi-Shing Shieh, Shine-Gwo Shiah
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 11, Pp 554-565 (2020)
The cytokine-inducible Src homology 2-containing protein (CISH) is an endogenous suppressors of signal transduction and activator of transcription (STAT) and acts as a key negative regulator of inflammatory cytokine responses. Downregulation of CISH
Externí odkaz:
https://doaj.org/article/9267c7d697d44d3a92d2e4a73c84f69e
Autor:
Shine-Gwo Shiah, Jenn-Ren Hsiao, Hsiao-Ju Chang, Yuan-Ming Hsu, Guan-Hsun Wu, Hsuan-Yu Peng, Sung-Tau Chou, Ching-Chuan Kuo, Jang-Yang Chang
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-13 (2020)
Abstract Background Epigenetic silencing of retinoic acid (RA) signaling-related genes have been linked with the pathogenesis and clinical outcome in oral squamous cell carcinoma (OSCC) carcinogenesis. However, the precise mechanisms underlying the a
Externí odkaz:
https://doaj.org/article/8eb2b9f459944aa48d0ec169c427c2d6
Autor:
Yi-Hong Liu, Yu-Lian Chen, Ting-Yu Lai, Ying-Chieh Ko, Yu-Fu Chou, Peir-Rong Chen, Jenn-Ren Hsiao, Jang-Yang Chang, Shine-Gwo Shiah, Jeng-Woei Lee, Jia-Ling Yang, Su-Fang Lin
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundPartial epithelial-mesenchymal transition (p-EMT) is a distinct clinicopathological feature prevalent in oral cavity tumors of The Cancer Genome Atlas. Located at the invasion front, p-EMT cells require additional support from the tumor str
Externí odkaz:
https://doaj.org/article/c5c66b95121f48e0859d1730794ad5c4
Autor:
Sung-Tau Chou, Hsuan-Yu Peng, Kuan-Chi Mo, Yuan-Ming Hsu, Guan-Hsun Wu, Jenn-Ren Hsiao, Su-Fang Lin, Horng-Dar Wang, Shine-Gwo Shiah
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Discoidin domain receptor-1 (DDR1) tyrosine kinase is highly expressed in a variety of human cancers and involved in various steps of tumorigenesis. However, the precise mechanisms underlying the abnormal expression of DDR1 in ora
Externí odkaz:
https://doaj.org/article/153c868dcc614b069a17bec55af4cc54
Autor:
Chu-Yen Chien, Ying-Chen Chen, Chia-Chen Hsu, Yu-Ting Chou, Shine-Gwo Shiah, Shyun-Yeu Liu, Alexander Cheng-Ting Hsieh, Ching-Yu Yen, Chien-Hsing Lee, Yi-Shing Shieh
Publikováno v:
Cells, Vol 10, Iss 8, p 2080 (2021)
Cigarette smoking is a significant risk factor for the development and progression of oral cancer. Previous studies have reported an association between nicotine and malignancy in oral cancer. Recent studies have also demonstrated that nicotine can i
Externí odkaz:
https://doaj.org/article/e1a64543364f4b869d729fec08a1de80
TNF-α-induced miR-450a mediates TMEM182 expression to promote oral squamous cell carcinoma motility.
Autor:
En-Wei Hsing, Shine-Gwo Shiah, Hsuan-Yu Peng, Ya-Wen Chen, Chih-Pin Chuu, Jenn-Ren Hsiao, Ping-Chiang Lyu, Jang-Yang Chang
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213463 (2019)
Distant metastasis leads oral cancer patients into a poor survival rate and a high recurrence stage. During tumor progression, dysregulated microRNAs (miRNAs) have been reported to involve tumor initiation and modulate oral cancer malignancy. MiR-450
Externí odkaz:
https://doaj.org/article/b6c5a32b3d324078876fe5fbd106b214
Autor:
Hsuan-Yu Peng, Yun-Ching Cheng, Yuan-Ming Hsu, Guan-Hsun Wu, Ching-Chuan Kuo, Jing-Ping Liou, Jang-Yang Chang, Shiow-Lian Catherine Jin, Shine-Gwo Shiah
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158440 (2016)
Microtubule inhibitors have been shown to inhibit Janus kinase 2/signal transducer and activator of transcription 3 (JAK2/STAT3) signal transduction pathway in various cancer cells. However, little is known of the mechanism by which the microtubule i
Externí odkaz:
https://doaj.org/article/ad73fcf91c054cb490d13e16a9687a2c