Zobrazeno 1 - 10 of 20 pro vyhledávání: '"Shindu C. Thomas"'
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Akademický článek
Exosomes: Biological Pharmaceutical Nanovectors for Theranostics
Autor: Shindu C. Thomas, Jin-Woo Kim, Giovanni M. Pauletti, Daniel J. Hassett, Nalinikanth Kotagiri
Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 9 (2022)
Exosomes are natural cell-derived nanovesicles of endocytic origin that enable cellular crosstalk by transferring encapsulated molecular cargos across biological barriers, thereby holding significantly complex implications in the etiology and progres
Externí odkaz: https://doaj.org/article/916a433a9b7d4b97a7a0052fb080ffe8
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Radiolabelled Bacterial Metallophores as Targeted PET Imaging Contrast Agents for Accurate Identification of Bacteria and Outer Membrane Vesicles in vivo
Autor: Shindu C. Thomas, Nabil A. Siddiqui, Hailey A. Houson, Daniel J. Hassett, Suzanne E. Lapi, Robert O’Donnell, Nalinikanth Kotagiri, Jose R. Blanco
Modern technologies such as 16s DNA sequencing capable of identifying microbes and provide taxonomic resolution at species and strain-specific levels is destined to be transformative1. Likewise, there is an emerging need to accurately identify both i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f72b438e3e79f3a0537784d29f93a1e6
https://doi.org/10.1101/2020.08.06.240119
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WITHDRAWN: Appraisal of Bone Targeting Potential of Nanohydroxyapatite Based Drug Carriers Conjugated with Pamidronate in Osteoporosis Treatment
Autor: Sushama Talegaonkar, Purnima Rawat, Shindu C. Thomas, Farhan Jalees Ahmad
Publikováno v: Pharmaceutical Nanotechnology.
Bentham Science has decided to withdraw this article from the journal in accordance with BSP Editorial Policies and apologizes to its readers for any inconvenience this may cause. BENTHAM SCIENCE DISCLAIMER: It is a condition of publication that manu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e0a9b4e89cf6c8f0a85e2069734e11
https://doi.org/10.2174/2211738507666191205141718
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Engineered Bacteria Enhance Immunotherapy and Targeted Therapy through Stromal Remodeling of Tumors
Autor: Giovanni M. Pauletti, Shindu C. Thomas, Nabil A. Siddiqui, Nitin S. Kamble, Tushar Madaan, Nalinikanth Kotagiri
Publikováno v: Adv Healthc Mater
Desmoplastic solid tumors are characterized by the rapid build-up of extracellular matrix (ECM) macromolecules, such as hyaluronic acid (HA). The resulting physiological barrier prevents the infiltration of immune cells and also impedes the delivery
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6178d2894c55c6037cf5f9bbd47d8b94
https://doi.org/10.1002/adhm.202101487
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Lutein, a versatile phyto-nutraceutical: An insight on pharmacology, therapeutic indications, challenges and recent advances in drug delivery
Autor: Sushama Talegaonkar, Tushar Madaan, Shindu C. Thomas, Suman Gyenwalee, Andleeb Nikhat Choudhary, Harshita Mishra, Mohammad Tariq, Divya Vohora
Publikováno v: PharmaNutrition. 5:64-75
Carotenoids are natural pigments known for their ability to provide protection from ultraviolet radiation and singlet-oxygen-induced damage such as mutation, immunosuppression, and oxidative stress induction. Lutein is a xanthophyll of the carotenoid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cbd36cfb0c34024eeb95d781ad633f77
https://doi.org/10.1016/j.phanu.2017.02.005
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Developed and validated stability indicating HPLC method for the determination of epirubicin in bulk drug, marketed injection and polymeric nanoparticles
Autor: Anu T. Singh, Shindu C. Thomas, Mohammad Tariq, Sushama Talegaonkar
Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Volume: 54, Issue: 4, Article number: e17515, Published: 08 APR 2019
Brazilian Journal of Pharmaceutical Sciences; Vol. 54 No. 4 (2018); e17515
Brazilian Journal of Pharmaceutical Sciences; Vol. 54 Núm. 4 (2018); e17515
Brazilian Journal of Pharmaceutical Sciences; v. 54 n. 4 (2018); e17515
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss 4 (2019)
Present work is aimed to develop a simple, sensitive, robust and reliable HPLC method for routine quality control of epirubicin (EPI) in bulk drug, marketed injections and polymeric nanoparticles. Separation was carried out by C18 column. Isocratic e
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eb3ec7c48db9da0a65f2be01c2004e2
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000400619&lng=en&tlng=en
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Revisiting bone targeting potential of novel hydroxyapatite based surface modified PLGA nanoparticles of risedronate: Pharmacokinetic and biochemical assessment
Autor: Shweta Pandey, Sushama Talegaonkar, Divya Vohora, Purnima Rawat, Farhan Jalees Ahmad, Shindu C. Thomas, Iqbal Ahmad, Sarika Gupta
Publikováno v: International Journal of Pharmaceutics. 506:253-261
Hydroxyapatite based biodegradable mPEG-PLGA nanoparticles of risedronate (mPEG-PLGA-RIS-HA) were prepared by water miscible dialysis method for synergistic treatment of osteoporosis. The bone targeting potential of prepared nanoparticles was evaluat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7573d0a2a63379a016d2d2b761b9615
https://doi.org/10.1016/j.ijpharm.2016.04.049
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Box-Behnken Design of Experiment Assisted Development and Optimization of Bendamustine HCl loaded Hydroxyapatite Nanoparticles
Autor: Sushama Talegaonkar, Tushar Madaan, Shindu C. Thomas, Zeenat Iqbal
Publikováno v: Current drug delivery. 15(9)
Background Bendamustine HCl, an antineoplastic drug, has a very short life of about 40 minutes which necessitates administration of large doses which leads to increased side effects as well as costs. Objective The present work describes the fabricati
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e964aff1a2470d29f7b0b23492a921d3
https://pubmed.ncbi.nlm.nih.gov/29929464
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