Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shinako Takada"'
Autor:
Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein, Chai-An Mao
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-23 (2018)
Abstract Background Mitochondrial dysfunction has been implicated in the pathologies of a number of retinal degenerative diseases in both the outer and inner retina. In the outer retina, photoreceptors are particularly vulnerable to mutations affecti
Externí odkaz:
https://doaj.org/article/86e23958dde9462c9e095325aaa44ae2
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5103 (2009)
More than 80% of mammalian protein-coding genes are driven by TATA-less promoters which often show multiple transcriptional start sites (TSSs). However, little is known about the core promoter DNA sequences or mechanisms of transcriptional initiation
Externí odkaz:
https://doaj.org/article/bdb871fae42743ff96571cc2a5fc8715
Autor:
Chai An Mao, William H. Klein, Takae Kiyama, Zhenlin Ju, Jing Wang, Ching-Kang Chen, Shinako Takada, Steven W. Wang, Ping Pan
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-23 (2018)
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-23 (2018)
Background Mitochondrial dysfunction has been implicated in the pathologies of a number of retinal degenerative diseases in both the outer and inner retina. In the outer retina, photoreceptors are particularly vulnerable to mutations affecting mitoch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd8d926389afb522a0df46b71050dc99
https://doi.org/10.1186/s13024-018-0287-z
https://doi.org/10.1186/s13024-018-0287-z
Autor:
Dagmar M. Truckses, Tatsushi Matsumura, Naoko Tanese, Raymond H. Jacobson, Shinako Takada, Xiaoping Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 104:7839-7844
TBP-associated factor 4 (TAF4), an essential subunit of the TFIID complex acts as a coactivator for multiple transcriptional regulators, including Sp1 and CREB. However, little is known regarding the structural properties of the TAF4 subunit that lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef643873f4ca90b02735545520034db
https://doi.org/10.1073/pnas.0608570104
https://doi.org/10.1073/pnas.0608570104
Publikováno v:
Proceedings of the National Academy of Sciences. 104:1189-1194
TFIID is an essential factor required for RNA polymerase II transcription but remains poorly understood because of its intrinsic complexity. Human TAF5, a 100-kDa subunit of general transcription factor TFIID, is an essential gene and plays a critica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512a84ce8db355b85850c4e1fe7d7687
https://doi.org/10.1073/pnas.0610297104
https://doi.org/10.1073/pnas.0610297104
Publikováno v:
Oncogene. 18:6965-6973
Hepatitis B virus (HBV) X protein activates many viral and cellular genes in trans and functional disruption of the p53 tumor suppressor gene product occurs when X protein is transiently expressed in the cytoplasm of cultured cells. We have carried o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7120b372eb2cb826e918818b4b5f5de
https://doi.org/10.1038/sj.onc.1203188
https://doi.org/10.1038/sj.onc.1203188
Publikováno v:
Genes to Cells. 3:477-484
Background Hepatitis B virus (HBV) infection is closely related to the development of not only acute or chronic hepatitis, but also hepatocellular carcinoma. Among the HBV genes, the X gene has been implicated in the carcinogenicity of this virus as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d402fea843f70d10a62e64a0be87475
https://doi.org/10.1046/j.1365-2443.1998.00203.x
https://doi.org/10.1046/j.1365-2443.1998.00203.x
Publikováno v:
Cell. 91(1):71-83
Eukaryotic cells are thought to contain a single TATA-binding protein (TBP) that directs transcription by cellular RNA polymerases. Here we report a cell type–specific TBP-related factor (TRF) that can form a stable TRF/IIA/IIB TATA DNA complex and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ace7e37bb07f774dc787b24006bdf68
Publikováno v:
Virology. 216(1):80-89
Hepatitis B virus (HBV) X gene is known to exhibit a transcriptional activation function and is considered to play a major role in hepatocarcinogenesis. We determined a 20-bp promoter element for the HBV X gene transcription and found a binding prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::708bf3b0c75a234d9a41bf7b50b4a642
Autor:
Toshifumi Hara, Kozo Ishidate, Hiroshi Kuwasawa, Hiroaki Kato, Shinako Takada, Yukihiko Aramaki, Katsuro Koike, Seishi Tsuchiya
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1278(1):51-58
Effects of fusogenic and DNA-binding amphiphilic compounds on the receptor-mediated gene transfer using asialofetuin-labeled liposomes (AF-liposomes) were examined with HepG2 cells and rat hepatocytes in primary culture. AF-liposomes were sufficientl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b9d76f72ccd6591ddb36a83144231cc