Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shinai Lee"'
Autor:
Eunhee Lee, Yong-Gyu Son, Shinai Lee, Yangmi Lim, Jonghwa Won, Sumyeong Park, Jiseon Yoo, Youngil Koh, Dong-Yeop Shin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 10 (2023)
Background Acute myeloid leukemia (AML) is a type of leukemia in adults with a high mortality rate and poor prognosis. Although targeted therapeutics, chemotherapy, and hematopoietic stem cell transplantation can improve the prognosis, the recurrence
Externí odkaz:
https://doaj.org/article/cc1ad51e12d040fa80953ba783a4336c
Autor:
Wenqing Jiang, Zhengyi Wang, Jaeho Jung, Hyunjoo Kim, Eunsil Sung, Jaehyoung Jeon, Youngkwang Kim, Shinai Lee, Yangmi Lim, Jonghwa Won, Uijung Jung, Hyung-Seung Jin, Gihoon You
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/f2416e2fe6da445a8a372f7dee52ac8d
Autor:
Lei Fang, Wenqing Jiang, Zhengyi Wang, Su-Hyung Park, Eui-Cheol Shin, Minwoo Jeon, Jaeho Jung, Hyunjoo Kim, Hyung-Don Kim, Shin Hwang, Seongju Jeong, Eunyoung Park, Eunsil Sung, Jaehyoung Jeon, Youngkwang Kim, Ui-jung Jung, Yong-Gyu Son, Youngeun Hong, Hanbyul Lee, Shinai Lee, Yangmi Lim, Jonghwa Won
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Background Stimulation of 4-1BB with agonistic antibodies is a promising strategy for improving the therapeutic efficacy of immune checkpoint inhibitors (ICIs) or for overcoming resistance to ICIs. However, dose-dependent hepatotoxicity was observed
Externí odkaz:
https://doaj.org/article/f928715e9bd14a19be6842809c144bf9
Autor:
Aerin Yoon, Shinai Lee, Sua Lee, Sojung Lim, Yong-Yea Park, Eunjung Song, Dong-Sik Kim, Kisu Kim, Yangmi Lim
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 399 (2020)
As mesothelin is overexpressed in various types of cancer, it is an attractive target for therapeutic antibodies. T-cell bispecific antibodies bind to target cells and engage T cells via binding to CD3, resulting in target cell killing by T-cell acti
Externí odkaz:
https://doaj.org/article/908d6af7d96f4de19914b881dc4fb2c7
Autor:
Seung-Woo Lee, Shinai Lee, Wonjun Son, Eunyoung Park, Yunji Park, Park Kyeongsu, Sora Kim, Ji-Hae Kim, Yeon-Woo Kang, Yangsoon Lee, Jonghwa Won, Han Wook Park, Yong-Gyu Son, Jung Uijung, Young-Min Kim, Dain Moon, Gihoon You, Hyekang Kim, Eom Jaehyun, Chung Hyejin, Jaeho Jung
Publikováno v:
Science Advances. 7
Cancer immunotherapy with 4-1BB agonists has limited further clinical development because of dose-limiting toxicity. Here, we developed a bispecific antibody (bsAb; B7-H3×4-1BB), targeting human B7-H3 (hB7-H3) and mouse or human 4-1BB, to restrict t
Autor:
Gihoon, You, Yangsoon, Lee, Yeon-Woo, Kang, Han Wook, Park, Kyeongsu, Park, Hyekang, Kim, Young-Min, Kim, Sora, Kim, Ji-Hae, Kim, Dain, Moon, Hyejin, Chung, Wonjun, Son, Ui-Jung, Jung, Eunyoung, Park, Shinai, Lee, Yong-Gyu, Son, Jaehyun, Eom, Jonghwa, Won, Yunji, Park, Jaeho, Jung, Seung-Woo, Lee
Publikováno v:
Science Advances
Tumor-targeted T cell costimulatory antibody augments antitumor immunity by enhancing tumor-killing T cells within the tumor.
Cancer immunotherapy with 4-1BB agonists has limited further clinical development because of dose-limiting toxicity. He
Cancer immunotherapy with 4-1BB agonists has limited further clinical development because of dose-limiting toxicity. He
Autor:
Hyung-Seung Jin, Gihoon You, Hyunjoo Kim, Yangmi Lim, Jung Uijung, Jeon Jaehyoung, Eunsil Sung, Shinai Lee, Jaeho Jung, Jiang Wenqing, Zhengyi Wang, Jonghwa Won, Kim Youngkwang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundPD-(L)1 inhibitor has revolutionized cancer treatment, but there are unmet clinical needs for PD-(L)1 inhibitor-resistant/refractory patients. Activation of T cells in tumor microenvironment by 4-1BB agonist antibodies is one of the promisi
Autor:
Minwoo Jeon, Han-Byul Lee, Seongju Jeong, Shin Hwang, Hyung-Don Kim, Zhengyi Wang, Hyunjoo Kim, Su-Hyung Park, Eun-Sil Sung, Jung Uijung, Jeon Jaehyoung, Eui-Cheol Shin, Yangmi Lim, Shinai Lee, Jiang Wenqing, Kim Youngkwang, Eunyoung Park, Youngeun Hong, Fang Lei, Son Yonggyu, Jonghwa Won, Jaeho Jung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 7 (2021)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundStimulation of 4-1BB with agonistic antibodies is a promising strategy for improving the therapeutic efficacy of immune checkpoint inhibitors (ICIs) or for overcoming resistance to ICIs. However, dose-dependent hepatotoxicity was observed i
Autor:
Gihoon You1, Yangsoon Lee2, Yeon-Woo Kang1, Han Wook Park1, Kyeongsu Park2, Hyekang Kim1, Young-Min Kim1, Sora Kim1, Ji-Hae Kim3, Dain Moon1, Hyejin Chung2, Wonjun Son2, Ui-jung Jung2, Eunyoung Park2, Shinai Lee2, Yong-Gyu Son2, Jaehyun Eom2, Jonghwa Won2, Yunji Park1, Jaeho Jung2 jaeho.jung@ablbio.com
Publikováno v:
Science Advances. 1/13/2021, Vol. 7 Issue 3, p1-15. 15p.