Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shina Pashova"'
Publikováno v:
Pharmacia, Vol 70, Iss 4, Pp 1439-1447 (2023)
The role of peptide probes’ conformational flexibility in extracting immunosignatures has not been sufficiently studied. Immunosignatures profile the antibody diversity and prove promising for early cancer detection and multi-disease diagnostics. A
Externí odkaz:
https://doaj.org/article/c9db73a374874730980f53002446b7bd
Autor:
Shina Pashova, Lubomir Balabanski, Gabriel Elmadjian, Alexey Savov, Elena Stoyanova, Velizar Shivarov, Peter Petrov, Anastas Pashov
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The typical anti-phospholipid antibodies (APLA) in the anti-phospholipid syndrome (APS) are reactive with the phospholipid-binding protein β2GPI as well as a growing list of other protein targets. The relation of APLA to natural antibodies and the f
Externí odkaz:
https://doaj.org/article/b25d9f3a07484fe183857b38853ec79c
Autor:
Anastas Pashov, Velizar Shivarov, Maya Hadzhieva, Victor Kostov, Dilyan Ferdinandov, Karen-Marie Heintz, Shina Pashova, Milena Todorova, Tchavdar Vassilev, Thomas Kieber-Emmons, Leonardo A. Meza-Zepeda, Eivind Hovig
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Specific antibody reactivities are routinely used as biomarkers, but the antibody repertoire reactivity (igome) profiles are still neglected. Here, we propose rationally designed peptide arrays as efficient probes for these system level biomarkers. M
Externí odkaz:
https://doaj.org/article/b42d87ee4a3c4e5fa4d5e1a1f52e7e9b
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 2, Pp 314-322 (2017)
Large-scale profiling and monitoring of antibody repertoires is possible through next generation sequencing (NGS), phage display libraries and microarrays. These methods can be combined in a pipeline, which ultimately maps the antibody reactivities o
Externí odkaz:
https://doaj.org/article/ec4eef79969a4372a1aaba5efca1df78
Autor:
Drenka Trivanović, E. Kistanova, Aleksandra Jauković, Snejana Kestendjieva, Desislava Abadjieva, Michal Jeseta, Elena Stoyanova, Shina Pashova, Milena Kostadinova, Milena Mourdjeva, Tamara Kukolj
Publikováno v:
Stem Cell Reviews & Reports
Mesenchymal stem cells (MSC) have been considered the promising candidates for the regenerative and personalized medicine due to their self-renewal potential, multilineage differentiation and immunomodulatory capacity. Although these properties have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b32c023b2571129b0ceb3baa0c3bd4
Autor:
Ekaterina N. Gorshkova, Shina Pashova, Ekaterina A. Vasilenko, Tatiana S. Tchurina, Elizaveta A. Razzorenova, Olga V. Starkina, Petya Dimitrova, Anastas Pashov, Tchavdar Lubenov Vassilev
Publikováno v:
Pharmacology. 107(7-8)
Introduction: As has been shown previously, various protein-modifying agents can change the antigen-binding properties of immunoglobulins. However, induced polyspecificity of human secretory immunoglobulin A (sIgA) has not been previously characteriz
Autor:
Cyril Planchais, Srinivas V. Kaveri, Julie Rayes, Anastas Pashov, Sandrine Delignat, Aditi Varthaman, Shina Pashova, Sébastien Lacroix-Desmazes, Jagadeesh Bayry, Jordan D. Dimitrov
Publikováno v:
Cellular Immunology
Cellular Immunology, Elsevier, 2020, 355, pp.104151. ⟨10.1016/j.cellimm.2020.104151⟩
Cellular Immunology, Elsevier, 2020, 355, pp.104151. ⟨10.1016/j.cellimm.2020.104151⟩
B cells with regulatory properties (Bregs) were identified in human and in mice among different B-cell subsets. Their regulatory properties rely mainly on the production of anti-inflammatory cytokines, in particular IL10, IL-35 and TGFβ, and were ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f82d84dd136fdaade05519d1eb8836
https://hal.archives-ouvertes.fr/hal-03031743/document
https://hal.archives-ouvertes.fr/hal-03031743/document
Autor:
Dilyan Ferdinandov, Maya Hadzhieva, Thomas Kieber-Emmons, Eivind Hovig, Victor Kostov, Velizar Shivarov, Leonardo A. Meza-Zepeda, Anastas Pashov, Shina Pashova, Milena Todorova, Tchavdar L. Vassilev, Karen-Marie Heinz
Specific antibody reactivities are routinely used as biomarkers but the use of antibody repertoire profiles is still awaiting recognition. Here we suggest to expedite the adoption of this class of system level biomarkers by rationally designing a pep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a46eff1f0b9667ce4636f9a6e40b243
Publikováno v:
Human vaccinesimmunotherapeutics. 13(2)
Large-scale profiling and monitoring of antibody repertoires is possible through next generation sequencing (NGS), phage display libraries and microarrays. These methods can be combined in a pipeline, which ultimately maps the antibody reactivities o
Autor:
Teodora Daneva, Plamen Padeshki, Shina Pashova, Hristo Gagov, Radoslava Emilova, Volodia Georgiev
Publikováno v:
Open Life Sciences, Vol 8, Iss 2, Pp 97-106 (2013)
Downstream regulatory element antagonist modulator (DREAM) protein is a 31 kDa Ca2+-regulated transcriptional repressor. It functions as a silencer of the gene transcription. In low intracellular free Ca2+ concentration DREAM tightly binds to the dow