Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shin-ichiro Nitta"'
Autor:
Mari Hashimoto, Kaoru Kobayashi, Mio Watanabe, Yasuhiro Kazuki, Shoko Takehara, Asumi Inaba, Shin-ichiro Nitta, Naoto Senda, Mitsuo Oshimura, Kan Chiba
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 8, Pp 2060-2068 (2013)
Here, we studied the effects of cytochrome P450 (CYP)3A deficiency on the mRNA expression of genes encoding regulators of hepatic cholesterol levels using Cyp3a-knockout (Cyp3a−/−) mice. The mRNA expression levels of genes encoding enzymes involv
Externí odkaz:
https://doaj.org/article/f10fb157a5d4461698d9ef597ca925cd
Autor:
Ko Igami, Hiroki Kittaka, Mikako Yagi, Kazuhito Gotoh, Yuichi Matsushima, Tomomi Ide, Masataka Ikeda, Saori Ueda, Shin-Ichiro Nitta, Manami Hayakawa, Nakayama, Keiichi I., Masaki Matsumoto, Dongchon Kang, Takeshi Uchiumi
Publikováno v:
Life Science Alliance; Jul2024, Vol. 7 Issue 7, p1-15, 15p
Publikováno v:
Clinical Nutrition ESPEN. 55:20-29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b431238293006a2748003862f551270f
https://doi.org/10.1016/j.clnesp.2023.02.020
https://doi.org/10.1016/j.clnesp.2023.02.020
Autor:
Rika Ishikawa, Kosuke Saito, Hidehisa Tachiki, Ryoya Goda, Koji Arai, Hisao Shimizu, Tomohiro Andou, Kentaro Takahara, Hitoshi Uchiyama, Shin-ichiro Nitta, Masaaki Kakehi, Kozo Hayashi, Naohiro Katagiri, Keiko Kojima, Hisashi Fujita, Kazuhiro Tsuchinaga, Yoshiro Saito
Publikováno v:
Bioanalysis. 15:207-218
Background: Although the fit-for-purpose approach has been proposed for biomarker assay validation, practical data should be compiled to facilitate the predetermination of acceptance criteria. Methods: Immunoaffinity LC–MS was used to analyze gluca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee4a4f140e7c2d73421b053b810cca6f
https://doi.org/10.4155/bio-2022-0240
https://doi.org/10.4155/bio-2022-0240
Autor:
Yuchen Sun, Shin-ichiro Nitta, Kosuke Saito, Ryuta Hosogai, Keiko Nakai, Ryoya Goda, Hisao Shimizu, Hisashi Fujita, Masaaki Kakehi, Kazuyuki Murata, Takeru Yamaguchi, Takeshi Okuzono, Shinichi Yamane, Mitsuhiko Kawabata, Takayuki Matsunuma, Kentaro Takahara, Noriko Kato, Masaki Yamada, Tokuyuki Yoshida, Takao Inoue, Yoshiro Saito
Publikováno v:
Bioanalysis. 14(18)
Background: Many bioanalytical methods for antisense oligonucleotides (ASOs) using LC–MS have been reported. However, no data have been available on the reproducibility and robustness of a single bioanalytical method for ASOs. As such, in the curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05130eab8441e7d0a6a649cd46a4ec4
https://pubmed.ncbi.nlm.nih.gov/36408704
https://pubmed.ncbi.nlm.nih.gov/36408704
Autor:
Hirohiko Ohtsuka, Kazuaki Takahashi, Harumi Kitaura, Hitoshi Kandori, Kenta Danbayashi, Tomoaki Higuchi, Fumihiro Jinno, Shin-ichiro Nitta, Kanae Mori, Atsushi Iwai, Keiko Nakai, Kosuke Saito, Yoshiro Saito
Publikováno v:
The Journal of toxicological sciences. 47(5)
According to ICH S3A QA focusing on microsampling, its application should be avoided in main study animals for test drugs that could exacerbate hematological parameters with frequent blood sampling. However, no study has reported the effects of micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103c7d40e00881803fc3c1f1b4908f15
https://pubmed.ncbi.nlm.nih.gov/35527007
https://pubmed.ncbi.nlm.nih.gov/35527007
Autor:
Tsuyoshi Matsumura, Kota Asahina, Mariko Yamaoka, Mitsuhiko Kawabata, Rika Ishikawa, Saki Yamauchi, Takahiro Suga, Shin-Ichiro Nitta, Akemi Nagao, Yoshiro Saito, Hitoshi Uchiyama, Keiko Nakai, Koji Arai, Ryoya Goda, Kosuke Saito, Hidehisa Tachiki
Publikováno v:
Bioanalysis. 13(20)
Aim: Although the fit-for-purpose approach has been proposed for validation procedures and acceptance criteria for biomarker assays, practical biomarker assays to facilitate clinical application and regulatory documents on biomarker assays remain lim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4497f490959435aaef1d563bf40838a8
https://pubmed.ncbi.nlm.nih.gov/34696608
https://pubmed.ncbi.nlm.nih.gov/34696608
Autor:
Satoko Ueno, Koji Arai, Tomoko Hasunuma, Yoshiro Saito, Akira Nakayama, Shin-Ichiro Nitta, Kosuke Saito
Publikováno v:
Journal of pharmaceutical sciences. 108(11)
Amino acids and lipids are biomarkers used to assess the presence and severity of disease, as well as the toxicological response to drugs. Although upper-extremity venipuncture is a well-used standard technique, fingertip capillary sampling is a more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b800e8f6f95f7bf6068934bd651bcfe
https://pubmed.ncbi.nlm.nih.gov/31493412
https://pubmed.ncbi.nlm.nih.gov/31493412
Autor:
Kaoru Kobayashi, Hiraku Suzuki, Hidetaka Akita, Mari Hashimoto, Kan Chiba, Shoko Takehara, Yasuhiro Kazuki, Shin-ichiro Nitta, Mitsuo Oshimura
Publikováno v:
The AAPS journal. 20(3)
Cytochrome P450 3A (CYP3A) enzymes metabolize approximately half of all drugs on the market. Since the endogenous compounds 4β-hydroxycholesterol (4β-HC) and 25-hydroxycholesterol (25-HC) are generated from cholesterol via CYP3A enzymes, we examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f6c0f88adee5bd673ba18614fc13b0
https://pubmed.ncbi.nlm.nih.gov/29858698
https://pubmed.ncbi.nlm.nih.gov/29858698
Publikováno v:
Tetrahedron. 65:628-637
Zinc complexes of 31-epimerically pure 32,32,32-trifluoro-bacteriopheophorbide-d methyl ester were prepared and their self-aggregation was examined in 1% (v/v) dichloromethane and hexane by visible and circular dichroism spectroscopies. Both the synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d95d4f0dff4b994c997961392aa27094
https://doi.org/10.1016/j.tet.2008.11.015
https://doi.org/10.1016/j.tet.2008.11.015