Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Shin-ichiro Miyashita"'
Autor:
Shin-Ichiro Miyashita, Shura Karatsu, Mako Fujiishi, I Hsun Huang, Yuki Nagashima, Tamaki Morobishi, Keita Hosoya, Tsuyoshi Hata, Min Dong, Yoshimasa Sagane
Publikováno v:
Toxins, Vol 15, Iss 2, p 123 (2023)
Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, cleaves proteins involved in neurotransmitter release, thereby triggering flaccid paralyses, which are responsible for botulism. BoNT is classified into seven serotypes (BoNT/A-G); BoNT/
Externí odkaz:
https://doaj.org/article/58686070967a49ea84a574fb2f989e5c
Autor:
Hatim Thaker, Jie Zhang, Shin-Ichiro Miyashita, Vivian Cristofaro, SunHyun Park, Ali Hashemi Gheinani, Maryrose P Sullivan, Rosalyn M Adam, Min Dong
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009994 (2021)
Botulinum neurotoxins (BoNTs) are the most potent toxins known and are also utilized to treat a wide range of disorders including muscle spasm, overactive bladder, and pain. BoNTs' ability to target neurons determines their specificity, potency, and
Externí odkaz:
https://doaj.org/article/3cf69e782b1546cfb49dd11df51d67a4
Autor:
Linxiang Yin, Geoffrey Masuyer, Sicai Zhang, Jie Zhang, Shin-Ichiro Miyashita, David Burgin, Laura Lovelock, Shu-Fen Coker, Tian-Min Fu, Pål Stenmark, Min Dong
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000618 (2020)
Botulinum neurotoxins (BoNTs) are a family of bacterial toxins with seven major serotypes (BoNT/A-G). The ability of these toxins to target and bind to motor nerve terminals is a key factor determining their potency and efficacy. Among these toxins,
Externí odkaz:
https://doaj.org/article/52c3a12f800244d2a8262129b64d22b0
Autor:
Sicai Zhang, Geoffrey Masuyer, Jie Zhang, Yi Shen, Daniel Lundin, Linda Henriksson, Shin-Ichiro Miyashita, Markel Martínez-Carranza, Min Dong, Pål Stenmark
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
There are seven well-established types of Botulinum neurotoxins (BoNTs). Here the authors report the identification and characterization of a new type of BoNT—BoNT/X—which cleaves a different site on canonical BoNTs substrates and targets SNARE f
Externí odkaz:
https://doaj.org/article/890984c9d1754f06b679464c60eecc3a
Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizes
Autor:
Shin-Ichiro Miyashita, Yoshimasa Sagane, Takamasa Uchino, Shura Karatsu, Keita Hosoya, Ihsun Huang, Koichi Niwa, Toshihiro Watanabe, Yoichi Niimura, Tomonori Suzuki
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
This data article provides atomic force microscopy (AFM) amplitude images of botulinum toxin complex (TC) molecules produced by Clostridium botulinum serotype D strain. C. botulinum produces different-sized TC molecules, such as a complex of botulinu
Externí odkaz:
https://doaj.org/article/a34fb5aa944d4b85a9ec293f77573800
Publikováno v:
Nippon Shokuhin Kagaku Kogaku Kaishi. 70:25-31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95ae658faf4d2ffc34db58bbba999707
https://doi.org/10.3136/nskkk.nskkk-d-22-00036
https://doi.org/10.3136/nskkk.nskkk-d-22-00036
Autor:
Yongliang Fang, Andrew Y. Chang, Deeptak Verma, Shin-Ichiro Miyashita, Susan Eszterhas, Pyung-Gang Lee, Yi Shen, Lydia R. Davis, Min Dong, Chris Bailey-Kellogg, Karl E. Griswold
Publikováno v:
ACS Synthetic Biology. 12:153-163
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::683e8d2e4353ba2456e78c96131b41c2
https://doi.org/10.1021/acssynbio.2c00426
https://doi.org/10.1021/acssynbio.2c00426
Publikováno v:
Biochemical and Biophysical Research Communications. 637:240-246
Cholesterol-dependent cytolysin (CDC) is a bacterial toxin that binds to eukaryotic cholesterol-containing membranes, forms oligomeric complexes, and is inserted into the bilayer to create large aqueous pores. Recently, we reported a species-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e720ae0bb3dfe62838c7df20bcf627f0
https://doi.org/10.1016/j.bbrc.2022.11.043
https://doi.org/10.1016/j.bbrc.2022.11.043
Publikováno v:
Nippon Shokuhin Kagaku Kogaku Kaishi. 69:473-480
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25a8e1b36350b7dfa17c7f69f13e77b2
https://doi.org/10.3136/nskkk.69.473
https://doi.org/10.3136/nskkk.69.473
Autor:
I-Hsun Huang, Shin-Ichiro Miyashita, Tsuyoshi Hata, Shura Karatsu, Keita Hosoya, Yoshimasa Sagane
Publikováno v:
Biochemical and biophysical research communications. 632
Clostridium botulinum produces seven botulinum neurotoxin (BoNT) serotypes. In nature, BoNT exists as a part of the progenitor toxin complex (PTC) through associations with neurotoxin associated proteins (NAPs), including nontoxic nonhemagglutinin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5387cbb186f9d5cbd8b004838d35cc9
https://pubmed.ncbi.nlm.nih.gov/36201881
https://pubmed.ncbi.nlm.nih.gov/36201881