Zobrazeno 1 - 10
of 339
pro vyhledávání: '"Shin-ichiro Masunaga"'
Autor:
Shin-ichiro Masunaga, Yu Sanada, Takushi Takata, Hiroki Tanaka, Yoshinori Sakurai, Minoru Suzuki, Mitsunori Kirihata, Koji Ono
Publikováno v:
Journal of Radiation Research. 64:399-411
Human head and neck squamous cell carcinoma cells transfected with mutant TP53 (SAS/mp53) or neo vector (SAS/neo) were inoculated subcutaneously into left hind legs of nude mice. After the subcutaneous administration of a 10B-carrier, boronophenylala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33bd8249bbeca598cb9a25b70d6f255e
https://doi.org/10.1093/jrr/rrad001
https://doi.org/10.1093/jrr/rrad001
Autor:
Toshiaki Nakano, Mahmoud I Shoulkamy, Masataka Tsuda, Hiroyuki Sasanuma, Kouji Hirota, Minoru Takata, Shin-Ichiro Masunaga, Shunichi Takeda, Hiroshi Ide, Tadayoshi Bessho, Keizo Tano
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0234859 (2020)
Proteins are covalently trapped on DNA to form DNA-protein cross-links (DPCs) when cells are exposed to DNA-damaging agents. Aldehyde compounds produce common types of DPCs that contain proteins in an undisrupted DNA strand. Tyrosyl-DNA phosphodieste
Externí odkaz:
https://doaj.org/article/e46da9f5427340498e7c36d9b12cb89d
Autor:
Tsubasa Watanabe, Tomohiro Yoshikawa, Hiroki Tanaka, Yuko Kinashi, Genro Kashino, Shin-ichiro Masunaga, Toshimitsu Hayashi, Koki Uehara, Koji Ono, Minoru Suzuki
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6920cc928be9b9a299550dc7b94efa7
https://doi.org/10.1007/s13318-023-00830-y
https://doi.org/10.1007/s13318-023-00830-y
Autor:
Koji Takeuchi, Yoshihide Hattori, Shinji Kawabata, Gen Futamura, Ryo Hiramatsu, Masahiko Wanibuchi, Hiroki Tanaka, Shin-ichiro Masunaga, Koji Ono, Shin-Ichi Miyatake, Mitsunori Kirihata
Publikováno v:
Cells, Vol 9, Iss 6, p 1551 (2020)
Boron neutron capture therapy (BNCT) is a form of tumor-cell selective particle irradiation using low-energy neutron irradiation of boron-10 (10B) to produce high-linear energy transfer (LET) alpha particles and recoiling 7Li nuclei (10B [n, alpha] 7
Externí odkaz:
https://doaj.org/article/9ad46844f331468b87ffb73bbbf9084b
Autor:
Shin-ichiro Masunaga, Minoru Suzuki, Hiroki Tanaka, Takushi Takata, Tsubasa Watanabe, Yoshinori Sakurai, Yu Sanada
Publikováno v:
International Journal of Radiation Biology. 97:1441-1449
Purpose To examine whether hypoxia and Hif-1α affect sensitivity of murine squamous cell carcinoma cells to boron neutron capture therapy (BNCT). Materials and methods SCC VII and SCC VII Hif-1α-deficient mouse tumor cells were incubated under norm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f17b7f46e004c634b4784345f3f546
https://doi.org/10.1080/09553002.2021.1956004
https://doi.org/10.1080/09553002.2021.1956004
Selective cytotoxicity of the anti-diabetic drug, metformin, in glucose-deprived chicken DT40 cells.
Autor:
Kei Kadoda, Takahito Moriwaki, Masataka Tsuda, Hiroyuki Sasanuma, Masamichi Ishiai, Minoru Takata, Hiroshi Ide, Shin-Ichiro Masunaga, Shunichi Takeda, Keizo Tano
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185141 (2017)
Metformin is a biguanide drug that is widely used in the treatment of diabetes. Epidemiological studies have indicated that metformin exhibits anti-cancer activity. However, the molecular mechanisms underlying this activity currently remain unclear.
Externí odkaz:
https://doaj.org/article/ad7e64ff3a7e4adab1e9b9eca882b95a
Autor:
Masayuki Nashimoto, Atsuko Shinohara, Minoru Suzuki, Yoshitaka Furuya, Minoru Ono, Ryouji Mizumachi, Novriana Dewi, Koji Ono, Shin-ichiro Masunaga, Yuuji Murata, Hiroyuki Takahashi, Hiroki Tanaka, Takumichi Sugihara, Haruo Yamauchi, Hironobu Yanagie, Yoshinori Sakurai, Hiroyuki Nakamura, Yasumasa Nonaka, Masashi Yanagawa, Yasuyuki Morishita, Jun Nakajima
Publikováno v:
In Vivo
Background/Aim: Tumor cell destruction by boron neutron capture therapy (BNCT) is attributed to the nuclear reaction between (10)B and thermal neutrons. The accumulation of (10)B atoms in tumor cells without affecting adjacent healthy cells is crucia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68036aaa013acb21c57af13d42ffcb91
https://doi.org/10.21873/invivo.12607
https://doi.org/10.21873/invivo.12607
Autor:
Hiroki Tanaka, Yoshinori Sakurai, Yu Sanada, Minoru Suzuki, Koji Ono, Takushi Takata, Shin-ichiro Masunaga, Keizo Tano
Publikováno v:
Journal of Radiation Research
Based on our previously published reports concerning the response of quiescent (Q) tumor cell populations to boron neutron capture therapy (BNCT), the heterogeneous microdistribution of 10B in tumors, which is influenced by the tumor microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb3d8e9b90bdfcc15eb341633a6409f
https://doi.org/10.1093/jrr/rraa048
https://doi.org/10.1093/jrr/rraa048
Autor:
Qin, Changyuan, Hou, Xuan, Khan, Thahomina, Nitta, Nobuhiro, Yanagawa, Masashi, Sakurai , Yuriko, Suzuki, Minoru, Shin‐Ichiro, Masunaga, Tanaka, Hiroki, Sakurai, Yoshinori, Takahashi, Hiroyuki, Aoki, Ichio, Yanagie, Hironobu, Nobuhiro, Nitta, Ichio, Aoki
Publikováno v:
ChemNanoMat. 6(3):412-419
Gadolinium(III) (Gd(III)) chelates are promising compounds for developing MRI‐guided neutron capture therapies (NCT). However, despite their success as MRI contrast agents (CAs), current Gd(III) chelates do not present appropriate accumulation in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::bcccd18a55f1cacc46f4aa82f359e784
https://repo.qst.go.jp/records/80043
https://repo.qst.go.jp/records/80043
Autor:
Minoru Suzuki, Xuan Hou, Yoshinori Sakurai, Nobuhiro Nitta, Hiroyuki Takahashi, Hironobu Yanagie, Yuriko Sakurai, Horacio Cabral, Shin-ichiro Masunaga, Thahomina Khan, Masashi Yanagawa, Changyuan Qin, Ichio Aoki, Hiroki Tanaka
Publikováno v:
ChemNanoMat. 6:412-419
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f20d8b00b8541856ac84722533f9b51a
https://doi.org/10.1002/cnma.201900730
https://doi.org/10.1002/cnma.201900730