Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Shin-ichiro Kawai"'
Autor:
Shin ichiro Kawai, Sucharita Das, Arthur H. Neufeld, Elizabeth Gachie, Smita C. Vora, Jane R Connor, Pamela T. Manning
Publikováno v:
Experimental Eye Research. 75:521-528
Following experimental, transient, retinal ischemia in the rat, there is loss of retinal neurons, which occurs over several weeks. Retinal ganglion cells (RGCs) are particularly susceptible and there is early, massive degeneration of these neurons af
Autor:
Shin-ichiro Kawai, Jane R. Connor, Arthur H. Neufeld, Pamela T. Manning, Smita C. Vora, Elizabeth Gachie, Sucharita Das
Publikováno v:
Journal of Glaucoma. 11:221-225
To test the hypothesis that nitric oxide, synthesized by inducible nitric oxide synthase, causes degeneration of retinal ganglion cells in an animal model of glaucoma.Rats with unilateral, chronic, moderately elevated intraocular pressure were treate
Autor:
Shigehiro Katayama, Ikuo Inoue, Masaru Sonoda, Kazuyuki Hirano, Toshiyuki Matsunaga, Takanori Nakajima, Shigeru Hokari, Shin-ichiro Kawai, Iwao Koyama, Tsugikazu Komoda
Publikováno v:
Journal of Biochemistry. 130:285-293
Peroxynitrite has been implicated in the oxidative modification of low-density lipoprotein (LDL) particles, and nitrotyrosine residues in the LDL have been detected in atherosclerotic plaques. Studies have suggested that lipoproteins modified by pero
Autor:
Toshiyuki Mastunaga, Takuya Awata, Shin-ichiro Kawai, Shigeru Hokari, Tugikazu Komoda, Ikuo Inoue, Shigehiro Katayama, Takanori Nakajima, Sei-ichi Goto, Kasumi Mizotani
Publikováno v:
Life Sciences. 67:863-876
We examined the effects of four 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (pravastatin, simvastatin, fluvastatin, and cerivastatin) on the production and expression of inflammatory cytokines and on enzyme expression involvi
Publikováno v:
Applied Organometallic Chemistry. 12:819-825
The concentration of tributyltin (TBT) in surface water from Osaka Bay ranged from 0.023 to 0.061 µg l−1 in 1989 and from not detected (ND) to 0.059 µg l−1 in 1990 while the proportion of TBT as a percentage of the total butyltins (BTs) was mor
Autor:
Takanori Nakajima, Tsugikazu Komoda, Shigehiro Katayama, Mari Yakushijin, Kiyohiko Negishi, Shin-ichiro Kawai, Kohtaro Oh-Ie, Iwao Koyama, Shigeru Hokari, Ikuo Inoue
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 121:417-423
We found previously that human bone alkaline phosphatase (AP) was glycated by aseptic incubation with glucose, and partially broken down by reactive oxygen species. In this study, we examined whether selective in vivo glycation of AP molecules occurr
Autor:
Atsuo Nagata, Takanari Nakano, Hidenori Takahashi, Shin-ichiro Kawai, Tsugikazu Komoda, Rina Shinozaki, Shuichi Miyazaki
Publikováno v:
Clinical biochemistry. 39(9)
Objectives Human free immunoglobulin light chains (FLCs) have long been considered as nonmeaningful spillover remnants from the process of immunoglobulin production; however, recent findings suggest that the antibody activity of FLCs may be involved
Autor:
Shin-ichiro Kawai, Shigeru Hokari, Toshiyuki Matsunaga, Takashi Miyazaki, Iwao Koyama, Tsugikazu Komoda
Publikováno v:
Comparative biochemistry and physiology. Part B, Biochemistrymolecular biology. 134(2)
A nucleotide phosphomonoesterase activity that preferably hydrolyzed dCMP was detected in rabbit liver and purified approximately 20-fold. The enzyme was similar in the catalytic and molecular properties to pyrimidine 5'-nucleotidase subclass I (P5N-
Autor:
Elizabeth Gachie, Arthur H. Neufeld, Smita C. Vora, Shin-ichiro Kawai, Bernard Becker, Sucharita Das
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15(7)
SPECIFIC AIMSWe have used a rat model of ischemia/reperfusion injury of the retina to study various risk factors that are relevant to neural injury in the human central nervous system (CNS). We have determined whether age, diet, diabetes, the presenc
Publikováno v:
Japanese journal of ophthalmology. 44(1)
Purpose: To evaluate the mobility of a hydroxyapatite implant covered with autologous sclera from the enucleated globes of patients with severe atrophy of the eyeball or eyelid retraction. Methods: This implant was used in seven patients with phthisi