Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shin-ichiro Iida"'
Autor:
Shin-ichiro Iida, Masayoshi Oh-eda, Koji Otabe, Yasufumi Kikuchi, Naoshi Fukushima, Masayuki Tsuchiya, Shinsuke Uno, Yasushi Yoshimura
Publikováno v:
Biochemical and Biophysical Research Communications. 315:912-918
We constructed a single-chain antibody fragment (scFv) of murine monoclonal antibody, MABL, which specifically bound to human CD47 (hCD47) and induced apoptosis of the leukemic cells. The scFv of MABL antibody with a 15-residue linker (MABL scFv-15)
Autor:
Yuka Morikawa, Shinʼichiro Iida, Shoji Hanada, Takuya Miura, Kazushige Inoue, Takashi Iwata, Hidetoshi Inoue, Yasuhiko Kobayashi
Publikováno v:
Journal of Bronchology & Interventional Pulmonology. 18:176-178
A 73-year-old man who had undergone surgery for lingual cancer, followed by radiation therapy and chemotherapy, presented with severe dyspnea. A chest radiograph revealed a left tension pneumothorax. An immediate tube thoracostomy alleviated his dysp
Publikováno v:
Biochemical Journal. 347:535-542
Mucin 2 (MUC2) is the major intestinal mucin. O-glycans are attached to MUC2 in a potentially diverse arrangement, which is crucial for their interaction with endogeneous and exogeneous lectins. In the present report, five oligopeptides [PTTTPITTTT(K
Publikováno v:
Journal of Biochemistry. 126:975-986
Mucins are major epithelial luminal surface proteins and function as a physical and biological barrier protecting mucous epithelia. Diverse glycosylation of mucins potentially provides a basis for tissue-specific interaction with the milieu. When muc
Publikováno v:
University of Copenhagen
An oligopeptide containing three consecutive Thr residues mimicking the tandem repeat portion of MUC2 (PTTTPLK) was investigated for the acceptor specificity to UDP-N-acetyl-D-galactosamine:peptide N-acetylgalactosaminyltransferase isozymes, UDP-N-ac
Publikováno v:
Journal of Biological Chemistry. 274:10697-10705
A fluorescein-labeled synthetic peptide, PTTTPITTTTK, was converted into O-glycosylated glycopeptides with various numbers of attachedN-acetyl-d-galactosamines (GalNAcs) by in vitro glycosylation with UDP-GalNAc and a microsomal fraction of LS174T hu
Publikováno v:
International Journal of Immunopharmacology. 17:973-980
An experimental tumor model was previously established in which BALB/c mice could survive the otherwise fatal intraperitoneal (i.p.) inoculation of BAMC-1 fibrosarcoma cells if the mice were treated with five sequential i.p. injections of OK-432 (a p
Autor:
Shin-ichiro Iida, Kenji Komuro, Akira Iwabuchi, Haruhiko Arai, Kiyoshi Yoshida, Hideo Nakajima, Makoto Sugimoto
Publikováno v:
TEION KOGAKU (Journal of Cryogenics and Superconductivity Society of Japan). 27:325-331
The friction resistance plays an important role to determine the amount of deflection between the wedges of toroidal coil cases of a nuclear fusion magnet under electromagnetic force, and the material combination showing high friction is required to
Autor:
Shin-ichiro Iida, Tomoyuki Igawa, Masahiko Nanami, Yuji Ishikawa, Masami Suzuki, Hiroyuki Tsunoda, Hisafumi Yamada-Okabe, Masayuki Tsuchiya, Shigeto Kawai, Toshiaki Tsunenari, Reiko F. Irie, Yumiko Azuma
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 13(9)
Purpose: L612, a human IgM monoclonal antibody produced by an EBV-transformed human B-cell line, binds to ganglioside GM3 and kills GM3-positive human melanoma cells in the presence of complement. It has been shown to be effective in some patients wi
Autor:
Shinsuke Uno, Hisafumi Yamada-Okabe, Yasufumi Kikuchi, Yasuko Kinoshita, Yumiko Azuma, Shin-ichiro Iida, Yasushi Yoshimura, Naoshi Fukushima, Toshiaki Tsunenari
Publikováno v:
Oncology Reports.
The ligation of CD47 induces the apoptosis of leukemic cells in a caspase-independent manner. We generated a monoclonal antibody against CD47 (mAb-MABL) that possibly induced apoptosis from the ligation of CD47 in CCRF-CEM and JOK-1 cells in vitro. T