Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Shin-ichi YOKOTA"'
Autor:
Kazuki Yamamoto, Toyotaka Sato, Aili Hao, Kenta Asao, Rintaro Kaguchi, Shintaro Kusaka, Radhakrishnam Raju Ruddarraju, Daichi Kazamori, Kiki Seo, Satoshi Takahashi, Motohiro Horiuchi, Shin-ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract MraY (phospho-N-acetylmuramoyl-pentapeptide-transferase) inhibitory natural products are attractive molecules as candidates for a new class of antibacterial agents to combat antimicrobial-resistant bacteria. Structural optimization of these
Externí odkaz:
https://doaj.org/article/8640ff4ee8c741c084f0f712332ebe3b
Autor:
Toyotaka Sato, Kojiro Uemura, Mitsuru Yasuda, Aiko Maeda, Toshifumi Minamoto, Kazuki Harada, Michiyo Sugiyama, Shiori Ikushima, Shin-ichi Yokota, Motohiro Horiuchi, Satoshi Takahashi, Testuo Asai
Publikováno v:
One Health, Vol 18, Iss , Pp 100715- (2024)
Transmission of antimicrobial-resistant bacteria among humans, animals, and the environment is a growing concern worldwide. The distribution of an international high-risk fluoroquinolone-resistant Escherichia coli clone, ST131, has been documented in
Externí odkaz:
https://doaj.org/article/ba4a934b73964ee4bd1d40dc70749108
Publikováno v:
Renal Replacement Therapy, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Background Dialysis units have been concerned that the corroded metal parts of pumps used in hemodialysis might not allow sterility of the pump to be ensured due to bacterial contamination, even after cleaning and disinfection are performed
Externí odkaz:
https://doaj.org/article/1f0a821f3e3948e9a7c1088780ebfdb2
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The mechanism underlying the anti-inflammatory effect of macrolide antibiotics, such as clarithromycin (CAM), remains to be clarified. The CAM-binding proteins 4-nitrophenylphosphatase domain and non-neuronal synaptosomal associated protein
Externí odkaz:
https://doaj.org/article/43bf99b1d64542faab465a714caf7503
Autor:
Shota Fukuzawa, Toyotaka Sato, Kotaro Aoki, Soh Yamamoto, Noriko Ogasawara, Chie Nakajima, Yasuhiko Suzuki, Motohiro Horiuchi, Satoshi Takahashi, Shin-ichi Yokota
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 22, Iss 1, Pp 1-18 (2023)
Abstract Background Colistin (CST) is a last-line drug for multidrug-resistant Gram-negative bacterial infections. CST-heteroresistant Enterobacter cloacae complex (ECC) has been isolated. However, integrated analysis of epidemiology and resistance m
Externí odkaz:
https://doaj.org/article/c31abc286faa490d977a79d980f717d7
Autor:
Takeshi Nakaya, Miyuki Yabe, Ellene H. Mashalidis, Toyotaka Sato, Kazuki Yamamoto, Yuta Hikiji, Akira Katsuyama, Motoko Shinohara, Yusuke Minato, Satoshi Takahashi, Motohiro Horiuchi, Shin-ichi Yokota, Seok-Yong Lee, Satoshi Ichikawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
MraY is a membrane enzyme required for bacterial cell wall synthesis. Here, the authors modify sphaerimicins as antibacterials targeting it via structure-based design and synthesis through two key reactions, showing a platform for further development
Externí odkaz:
https://doaj.org/article/16ee9423619a405db124dcc0caf62ed5
Autor:
Hiroki Kurumi, Tomoaki Takata, Tsutomu Kanda, Takaaki Sugihara, Tomoyuki Kakugawa, Shin-ichi Yokota, Tomohito Morisaki, Taro Akashi, Hajime Isomoto
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory disorders of the gastrointestinal tract that share similar genetic risk factors. However, while fibrotic stricture of the intestine is a major characteristic of CD;
Externí odkaz:
https://doaj.org/article/380b027949734f6b9050efd777ff8587
Autor:
Ayano Konno, Torahiko Okubo, Yoshiaki Enoeda, Tomoko Uno, Toyotaka Sato, Shin-Ichi Yokota, Rika Yano, Hiroyuki Yamaguchi
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0291765 (2023)
Healthcare-associated infections have become a major health issue worldwide. One route of transmission of pathogenic bacteria is through contact with "high-touch" dry surfaces, such as handrails. Regular cleaning of surfaces with disinfectant chemica
Externí odkaz:
https://doaj.org/article/7fff7917fedf4969926e4d59b7807612
Autor:
Yukari Fukushima, Toyotaka Sato, Naoyuki Tsukamoto, Chie Nakajima, Yasuhiko Suzuki, Satoshi Takahashi, Shin-ichi Yokota
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 27, Iss , Pp 150-155 (2021)
ABSTRACT: Objectives: Fluoroquinolone (FQ)- and third-generation cephalosporin-resistant Escherichia coli are increasing in Japan. In the early 2000s, the FQ-resistant E. coli clone ST131 increased in clinical settings worldwide. It frequently produc
Externí odkaz:
https://doaj.org/article/4173cdb2a2f04e898bd08dce5f4bb6f2
Autor:
Shinichi WATANABE, Megumi MIURA, Hiromi MORITA, Moeka NISHI, Shin-ichi YOKOTA, Shosaku HATTORI, Hiromichi MATSUMOTO, Emiko FUKUI, Ken Takeshi KUSAKABE, Masanori OCHI, Naomi NAKAGATA, Yasuo KISO, Chieko KAI, Midori YOSHIZAWA
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 4, Pp 265-272 (2021)
Advanced reproductive technologies are being applied for the propagation of squirrel monkeys, to ensure their preservation as a genetic resource and the effective use of their gametes in the future. In the present study, oocytes and spermatozoa were
Externí odkaz:
https://doaj.org/article/f8b9de966608437b9b04300b81979121