Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shin-ichi Kitani"'
Autor:
Seiji Hayashi, Yoshihide Kii, Mitsuyasu Tabo, Hitoshi Fukuda, Tetsuji Itoh, Takashi Shimosato, Hideto Amano, Mamoru Saito, Hajime Morimoto, Kiyoshi Yamada, Atsuhiro Kanda, Toshimasa Ishitsuka, Takanobu Yamazaki, Yoichi Kiuchi, Shinya Taniguchi, Tatsuya Mori, Shigekazu Shimizu, Yuji Tsurubuchi, Shun-ichi Yasuda, Shin-ichi Kitani, Chiaki Shimada, Kazuo Kobayashi, Masaharu Komeno, Chieko Kasai, Toshiyasu Hombo, Keiji Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 423-437 (2005)
To construct a non-clinical database for drug-induced QT interval prolongation, the electrophysiological effects of 11 positive and 10 negative compounds on action potentials (AP) in guinea-pig papillary muscles were investigated in a multi-site stud
Externí odkaz:
https://doaj.org/article/a0418258c79346d3ac043532653edbdc
Autor:
Ryuzaburo Yamazaki, Masayuki Yamada, Kazuo Kobayashi, Shin-ichi Kitani, Chiaki Shimada, Takashi Shimosato, Tatsuya Mori, Hideki Suganami, Keiji Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 439-447 (2005)
Sixteen pharmaceutical companies and 6 contract research organizations in QT PRODACT acquired data on the action potentials in isolated guinea-pig papillary muscles using a standard protocol established by the QT PRODACT. Inter- and intra-facility va
Externí odkaz:
https://doaj.org/article/5d109920ce4c49c4a140369e91a81f4d
Autor:
Kentaro Ando, Toshiyasu Hombo, Akihiro Kanno, Hironobu Ikeda, Masakazu Imaizumi, Noritsugu Shimizu, Kengo Sakamoto, Shin-ichi Kitani, Yoshinori Yamamoto, Shingo Hizume, Keiko Nakai, Tetsuya Kitayama, Keiji Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 487-500 (2005)
In safety pharmacology studies, the effects on the QT interval of electrocardiograms are routinely assessed using a telemetry system in cynomolgus monkeys. However, there is a lack of integrated databases concerning in vivo QT assays in conscious mon
Externí odkaz:
https://doaj.org/article/756283a326c14e85af378ba65971ec91
Autor:
Yoshihide Kii, Seiji Hayashi, Mitsuyasu Tabo, Takashi Shimosato, Hitoshi Fukuda, Tetsuji Itoh, Hideto Amano, Mamoru Saito, Hajime Morimoto, Kiyoshi Yamada, Atsuhiro Kanda, Toshimasa Ishitsuka, Takanobu Yamazaki, Yoichi Kiuchi, Shinya Taniguchi, Tatsuya Mori, Shigekazu Shimizu, Yuji Tsurubuchi, Shun-ichi Yasuda, Shin-ichi Kitani, Chiaki Shimada, Kazuo Kobayashi, Masaharu Komeno, Chieko Kasai, Toshiyasu Hombo, Keiji Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 449-457 (2005)
Certain compounds that prolong QT interval in humans have little or no effect on action-potential (AP) duration used traditionally, but they inhibit rapidly-activated-delayed-rectifier potassium currents (IKr) and/or human ether-a-go-go-related gene
Externí odkaz:
https://doaj.org/article/607f605ce3e84d8090d1635dfe43b73c
Autor:
Kazuo Kobayashi, Hideto Amano, Tetsuji Itoh, Mamoru Saito, Yoshihide Kii, Shinya Taniguchi, Yoichi Kiuchi, Takashi Shimosato, Shun-ichi Yasuda, Chieko Kasai, Yuji Tsurubuchi, Toshimasa Ishitsuka, Tatsuya Mori, Seiji Hayashi, Kiyoshi Yamada, Mitsuyasu Tabo, Hajime Morimoto, Chiaki Shimada, Hitoshi Fukuda, Shin-ichi Kitani, Atsuhiro Kanda, Keiji Yamamoto, Toshiyasu Hombo, Masaharu Komeno, Takanobu Yamazaki, Shigekazu Shimizu
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 423-437 (2005)
To construct a non-clinical database for drug-induced QT interval prolongation, the electrophysiological effects of 11 positive and 10 negative compounds on action potentials (AP) in guinea-pig papillary muscles were investigated in a multi-site stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f709bc0b147b24d29b688464309466
https://doi.org/10.1254/jphs.qt-a1
https://doi.org/10.1254/jphs.qt-a1
Autor:
Kazuo Kobayashi, Tatsuya Mori, Takashi Shimosato, Masayuki Yamada, Ryuzaburo Yamazaki, Shin-ichi Kitani, Hideki Suganami, Chiaki Shimada, Keiji Yamamoto
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 439-447 (2005)
Sixteen pharmaceutical companies and 6 contract research organizations in QT PRODACT acquired data on the action potentials in isolated guinea-pig papillary muscles using a standard protocol established by the QT PRODACT. Inter- and intra-facility va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7032215e5ace03f56d4dd77a74517a57
https://doi.org/10.1254/jphs.qt-b5
https://doi.org/10.1254/jphs.qt-b5
Autor:
Toshimasa Ishitsuka, Masaharu Komeno, Shin-ichi Kitani, Kazuo Kobayashi, Shinya Taniguchi, Shun-ichi Yasuda, Toshiyasu Hombo, Yuji Tsurubuchi, Yoshihide Kii, Hajime Morimoto, Keiji Yamamoto, Tatsuya Mori, Tetsuji Itoh, Takanobu Yamazaki, Kiyoshi Yamada, Chieko Kasai, Mitsuyasu Tabo, Takashi Shimosato, Chiaki Shimada, Atsuhiro Kanda, Hitoshi Fukuda, Hideto Amano, Yoichi Kiuchi, Mamoru Saito, Shigekazu Shimizu, Seiji Hayashi
Publikováno v:
Journal of Pharmacological Sciences, Vol 99, Iss 5, Pp 449-457 (2005)
Certain compounds that prolong QT interval in humans have little or no effect on action-potential (AP) duration used traditionally, but they inhibit rapidly-activated-delayed-rectifier potassium currents (IKr) and/or human ether-a-go-go-related gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f069beb63d777b3d1c3835ebb5eb7be
https://pubmed.ncbi.nlm.nih.gov/16493186
https://pubmed.ncbi.nlm.nih.gov/16493186