Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Shin-ichi KASHIWABARA"'
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 1, Pp 35-42 (2020)
Testis-brain RNA-binding protein (TB-RBP/Translin) is known to contribute to the translational repression of a subset of haploid cell-specific mRNAs, including protamine 2 (Prm2) mRNA. Mutant mice lacking TB-RBP display abnormal spermatogenesis, desp
Externí odkaz:
https://doaj.org/article/a0b780859f79449b8ffe22107a1df604
Autor:
Daichi KOKUBU, Ryousuke OOBA, Yukiko ABE, Hana ISHIZAKI, Shigeki YOSHIDA, Atsushi ASANO, Shin-ichi KASHIWABARA, Hitoshi MIYAZAKI
Publikováno v:
The Journal of Reproduction and Development, Vol 65, Iss 2, Pp 139-146 (2019)
Recently, gradual decline in human sperm production has become a serious worldwide concern because it leads to increased rates of infertility. Endocrine disrupters, lifestyle changes, and varicocele, all of which elevate testicular temperature, are t
Externí odkaz:
https://doaj.org/article/ce516f7c09464807863f5fa7ff7fce56
Publikováno v:
The Journal of Reproduction and Development
Testis-brain RNA-binding protein (TB-RBP/Translin) is known to contribute to the translational repression of a subset of haploid cell-specific mRNAs, including protamine 2 (Prm2) mRNA. Mutant mice lacking TB-RBP display abnormal spermatogenesis, desp
Autor:
Yukiko Abe, Atsushi Asano, Hana Ishizaki, Shigeki Yoshida, Shin-ichi Kashiwabara, Hitoshi Miyazaki, Daichi Kokubu, Ryousuke Ooba
Publikováno v:
The Journal of Reproduction and Development
Recently, gradual decline in human sperm production has become a serious worldwide concern because it leads to increased rates of infertility. Endocrine disrupters, lifestyle changes, and varicocele, all of which elevate testicular temperature, are t
Autor:
Shin-ichi Kashiwabara, Kanako Oyama, Tadashi Baba, Satsuki Tsuruta, Yutaro Yamaoka, Chieko Iwazaki
Publikováno v:
The Journal of Reproduction and Development
Mutant mice lacking a testis-specific cytoplasmic poly(A) polymerase, PAPOLB/TPAP, exhibit spermiogenesis arrest and male infertility. However, the mechanism by which PAPOLB regulates spermiogenesis remains unclear. In this study, we examined the rel
Autor:
Tadashi Baba, Satsuki Tsuruta, Shin-ichi Kashiwabara, Ayaka Saegusa, Keitaro Okada, Yu Miyagaki
Publikováno v:
The Journal of Reproduction and Development
Mouse testes contain several isoforms of cytoplasmic poly(A)-binding proteins (PABPCs), including ubiquitous PABPC1 and testis-specific PABPC2/PABPt. PABPC2 is characterized by its absence from translationally active polyribosomes and elongating sper
Publikováno v:
The Journal of Reproduction and Development
The testis-specific cytoplasmic poly(A) polymerase PAPOLB/TPAP is essential for spermatogenesis. Although this enzyme is responsible for poly(A) tail extension of a subset of mRNAs in round spermatids, the stability and translational efficiency of th
Autor:
Jaehyun Kim, Junnosuke Nakamura, Chiharu Hamada, Takumi Taketomi, Sarasa Yano, Tomomi Okajima, Shin-ichi Kashiwabara, Tadashi Baba, Ban Sato, Tomoki Chiba, Fuminori Tsurutaa
Publikováno v:
Molecular & Cellular Biology; Nov2020, Vol. 40 Issue 21, p1-16, 16p
Autor:
Atsuo Ogura, Yoshinori Kanemori, Hidetoshi Hasuwa, Yu Ishikawa, Tadashi Baba, Mai Sudo, Masahito Ikawa, Yoshitaka Koga, Kiyoshi Nagashima, Shin-ichi Kashiwabara, Narumi Ogonuki, Woojin Kang
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Proper biogenesis of a sperm-specific organelle, the acrosome, is essential for gamete interaction. An acrosomal matrix protein, ACRBP, is known as a proacrosin-binding protein. In mice, two forms of ACRBP, wild-type ACRBP-W and variant ACRBP-V5, are
Autor:
Masanori Kimura, Ekyune Kim, Shin-ichi Kashiwabara, Taiga Yamazaki, Woojin Kang, Tadashi Baba, Misuzu Yamashita, Mariko Saigo, Tomoko Nakanishi
Publikováno v:
Biology of Reproduction. 81:939-947
Although sperm entry into the oocyte-cumulus complex and subsequent sperm penetration through the cumulus matrix to reach the oocyte zona pellucida are essential for mammalian fertilization, the molecular mechanism remains controversial. Previously,