Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shin-Ya Isobe"'
Autor:
Shin-Ya Isobe, Shin-ichiro Hiraga, Koji Nagao, Hiroyuki Sasanuma, Anne D. Donaldson, Chikashi Obuse
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109383- (2021)
Summary: DNA double-strand breaks (DSBs) are repaired mainly by non-homologous end joining (NHEJ) or homologous recombination (HR). RIF1 negatively regulates resection through the effector Shieldin, which associates with a short 3′ single-stranded
Externí odkaz:
https://doaj.org/article/4755f742828b4ed48e35afdcc3b31afd
Publikováno v:
Cell Reports, Vol 20, Iss 2, Pp 297-307 (2017)
DNA double-strand breaks (DSBs) are repaired by either the homology-directed repair (HDR) or the non-homologous end-joining (NHEJ) pathway. RIF1 (RAP1-interacting factor homolog) was recently shown to stimulate NHEJ through an interaction with 53BP1
Externí odkaz:
https://doaj.org/article/7015b6ffe76a4a358bb5a8168ccc6603
Autor:
Mayu Isono, Atsuko Niimi, Takahiro Oike, Yoshihiko Hagiwara, Hiro Sato, Ryota Sekine, Yukari Yoshida, Shin-Ya Isobe, Chikashi Obuse, Ryotaro Nishi, Elena Petricci, Shinichiro Nakada, Takashi Nakano, Atsushi Shibata
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 520-532 (2017)
Summary: BRCA1 promotes homologous recombination (HR) by activating DNA-end resection. By contrast, 53BP1 forms a barrier that inhibits DNA-end resection. Here, we show that BRCA1 promotes DNA-end resection by relieving the 53BP1-dependent barrier. W
Externí odkaz:
https://doaj.org/article/c08217bfe8ec48588e34eb2bb7114e08
Autor:
Yukiko Kuroda, Aiko Iwata-Otsubo, Kerith-Rae Dias, Suzanna E.L. Temple, Koji Nagao, Lachlan De Hayr, Ying Zhu, Shin-Ya Isobe, Gohei Nishibuchi, Sarah K. Fiordaliso, Yuki Fujita, Alyssa L. Rippert, Samuel W. Baker, Marco L. Leung, Daniel C. Koboldt, Adele Harman, Beth A. Keena, Izumi Kazama, Gopinath Musuwadi Subramanian, Kandamurugu Manickam, Betsy Schmalz, Maeson Latsko, Elaine H. Zackai, Matt Edwards, Carey-Anne Evans, Matthew C. Dulik, Michael F. Buckley, Toshihide Yamashita, W. Timothy O'Brien, Robert J. Harvey, Chikashi Obuse, Tony Roscioli, Kosuke Izumi
Publikováno v:
Genetics in Medicine. :100861
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::914e271474db9b1e3cb13eb5db338d12
https://doi.org/10.1016/j.gim.2023.100861
https://doi.org/10.1016/j.gim.2023.100861
Autor:
Chikashi Obuse, Shin-Ya Isobe, Koji Nagao, Anne D. Donaldson, Hiroyuki Sasanuma, Shin-ichiro Hiraga
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109383-(2021)
Cell Reports
Cell Reports
Summary DNA double-strand breaks (DSBs) are repaired mainly by non-homologous end joining (NHEJ) or homologous recombination (HR). RIF1 negatively regulates resection through the effector Shieldin, which associates with a short 3′ single-stranded D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6301defb3955feb5c05b4e6ed5c57da
http://www.sciencedirect.com/science/article/pii/S2211124721007816
http://www.sciencedirect.com/science/article/pii/S2211124721007816
Autor:
Yukiko Kuroda, Aiko Iwata-Otsubo, Kerith-Rae Dias, Suzanna E.L. Temple, Koji Nagao, Lachlan De Hayr, Ying Zhu, Shin-Ya Isobe, Gohei Nishibuchi, Sarah K Fiordaliso, Yuki Fujita, Alyssa L. Rippert, Samuel W Baker, Marco L. Leung, Daniel C. Koboldt, Adele Harman, Beth A. Keena, Izumi Kazama, Gopinath Musuwadi Subramanian, Kandamurugu Manickam, Betsy Schmalz, Maeson Latsko, Elaine H Zackai, Matt Edwards, Carey-Anne Evans, Matthew C. Dulik, Michael F. Buckley, Toshihide Yamashita, W. Timothy O’Brien, Robert J. Harvey, Chikashi Obuse, Tony Roscioli, Kosuke Izumi
PurposeThis study aimed to establish variants inCBX1, encoding heterochromatin protein 1β (HP1β), as a cause of a novel syndromic neurodevelopmental disorder.MethodsPatients withCBX1variants were identified, and clinician researchers were connected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a114a2b1f179855b5c4d98e1b3863aff
https://doi.org/10.1101/2020.09.29.319228
https://doi.org/10.1101/2020.09.29.319228
Autor:
Ryota Sekine, Yoshihiko Hagiwara, Takashi Nakano, Takahiro Oike, Ryotaro Nishi, Chikashi Obuse, Mayu Isono, Elena Petricci, Shinichiro Nakada, Atsushi Shibata, Hiro Sato, Shin Ya Isobe, Atsuko Niimi, Yukari Yoshida
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 520-532 (2017)
Summary: BRCA1 promotes homologous recombination (HR) by activating DNA-end resection. By contrast, 53BP1 forms a barrier that inhibits DNA-end resection. Here, we show that BRCA1 promotes DNA-end resection by relieving the 53BP1-dependent barrier. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3594ac138518c29dd549d44af77f996f
http://hdl.handle.net/11365/1006807
http://hdl.handle.net/11365/1006807
Autor:
Sato, Koichi, Ishiai, Masamichi, Toda, Kazue, Furukoshi, Satoshi, Osakabe, Akihisa, Tachiwana, Hiroaki, Takizawa, Yoshimasa, Kagawa, Wataru, Kitao, Hiroyuki, Dohmae, Naoshi, Obuse, Chikashi, Kimura, Hiroshi, Takata, Minoru, Kurumizaka, Hitoshi
Publikováno v:
EMBO Journal; 8/29/2012, Vol. 31 Issue 17, p3524-3536, 13p, 2 Diagrams, 6 Graphs