Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Shin-Tai Chen"'
Autor:
Chun-Hsien Wu, Chin Heng Gan, Lan-Hui Li, Jen-Che Chang, Shin-Tai Chen, Mridula P. Menon, Shu-Meng Cheng, Shih-Ping Yang, Chen-Lung Ho, Oleg V. Chernikov, Chi-Hung Lin, Yulin Lam, Kuo-Feng Hua
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/2e4a50d8a0a74080ac3fc0e44d9c169c
Autor:
Chun-Hsien Wu, Chin Heng Gan, Lan-Hui Li, Jen-Che Chang, Shin-Tai Chen, Mridula P. Menon, Shu-Meng Cheng, Shih-Ping Yang, Chen-Lung Ho, Oleg V. Chernikov, Chi-Hung Lin, Yulin Lam, Kuo-Feng Hua
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Conjugated polyenes are a class of widely occurring natural products with various biological functions. We previously identified 4-hydroxy auxarconjugatin B (4-HAB) as anti‐inflammatory agent with an IC50 of ~20 µM. In this study, we synthesized a
Externí odkaz:
https://doaj.org/article/b3bedefcc0aa4acca5f8333fdfc9d21f
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101679 (2014)
RASSF1C is a major isoform of the RASSF1 gene, and is emerging as an oncogene. This is in contradistinction to the RASSF1A isoform, which is an established tumor suppressor. We have previously shown that RASSF1C promotes lung cancer cell proliferatio
Externí odkaz:
https://doaj.org/article/6c67de85c73a4179939ec06b7311d5b0
Autor:
Charles H Rundle, Shin-Tai Chen, Michael J Coen, Jon E Wergedal, Virginia Stiffel, Kin-Hing William Lau
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98004 (2014)
This study sought to determine if direct application of the lentiviral (LV)-cyclooxygenase 2 (COX2) vector to the tendon-bone interface would promote osteointegration of the tendon graft in a rat model of biceps tenodesis. The LV-COX2 gene transfer s
Externí odkaz:
https://doaj.org/article/5e34ba6353d2452eba7a0b0c919d86d4
Autor:
Shin-Tai Chen, Kuo-Feng Hua, Kai-Fa Huang, Jiahn-Haur Liao, Shih-Hsiung Wu, Wei-Ting Wong, I-Ming Lee
Publikováno v:
Chemical Communications. 57:6209-6212
Toll-like receptor 4 (TLR4) recognizes various protein ligands; however, the protein-TLR4 binding model is unclear. Here we demonstrate a Crenomytilus grayanus lectin (CGL)-TLR4/MD2 model to show that CGL interacts with a TLR4/myeloid differentiation
Autor:
Chun-Ru Hsu, I-Ming Lee, Jin-Town Wang, Yen-Ju Yang, Victor Johansson, Shin-Tai Chen, Jyh-Horng Sheu, Tzu-Yin Huang, Peter Konradsson, Shih-Hsiung Wu, Feng-Ling Yang, Pei-Fang Hsieh
Publikováno v:
Carbohydrate Polymers. 278:118944
Klebsiella pneumoniae serotype KN2 is a carbapenem-resistant strain and leads to the health care-associated infections, such as bloodstream infections. Its capsular polysaccharide (CPS) was isolated and cleaved by a specific enzyme from a bacteriopha
Publikováno v:
Journal of Cellular Biochemistry. 116:1785-1796
We have previously shown that PTP-oc is an enhancer of the functional activity of osteoclasts and that EphA4 is a suppressor. Here, we provide evidence that PTP-oc enhances osteoclast activity in part through inactivation of EphA4 by dephosphorylatin
Autor:
Fatima. Z. Alshbool, Gabriel R. Linares, David R. Powell, Shin-Tai Chen, Weirong Xing, Robert Brommage, K-H William Lau, Subburaman Mohan, Jon E. Wergedal
Publikováno v:
Journal of Bone and Mineral Research. 27:1553-1565
Claudin 18 (Cldn-18) belongs to a large family of transmembrane proteins that are important components of tight junction strands. Although several claudin members are expressed in bone, the functional role for any claudin member in bone is unknown. H
Publikováno v:
The Journal of Gene Medicine. 13:511-521
Background The present study aimed to develop a rat model of biceps tenodesis and to assess the feasibility of a lentiviral (LV)-based bone morphogenetic protein (BMP) 4 in vivo gene transfer strategy for healing of biceps tenodesis. Methods A rat mo
Autor:
Susan L. Hall, Shin-Tai Chen, Daila S. Gridley, Jon E. Wergedal, K.-H. William Lau, Subburaman Mohan
Publikováno v:
The Journal of Gene Medicine. 13:77-88
Background The present study assesses the effect of the stem cell antigen1 positive (Sca-1 + ) cell-based human growth hormone (hGH) ex vivo gene transfer strategy on endosteal bone mass in the mouse. Methods Sublethally irradiated recipien tm ice we