Zobrazeno 1 - 10
of 642
pro vyhledávání: '"Shin-Ichiro Nishimura"'
Autor:
Ken Murakami, Daiki Kambe, Yasuhiro Yokoi, Hajime Wakui, Shun Hayakawa, Nozomi Hirane, Ryosuke Koide, Michiru Otaki, Noriko Nagahori, Shin-Ichiro Nishimura
Publikováno v:
Advanced NanoBiomed Research, Vol 3, Iss 12, Pp n/a-n/a (2023)
Human neuraminidase‐1 (NEU1) plays a much more profound function in human cancers than previously considered. It is demonstrated that cancer cell surface NEU1 is a desired gatekeeper for an innovative anticancer therapeutic nanomedicine enabling ac
Externí odkaz:
https://doaj.org/article/3bc271e0d4c848948146342b54489a5a
Autor:
Lareno L. Villones, Anna-Kristin Ludwig, Hiroyuki Kumeta, Seiya Kikuchi, Rika Ochi, Tomoyasu Aizawa, Shin-Ichiro Nishimura, Hans-Joachim Gabius, Hiroshi Hinou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Dystroglycan (DG), which constitutes a part of the dystrophin–glycoprotein complex, connects the extracellular matrix to the cytoskeleton. The matriglycans presented by the extracellular α-DG serve as a contact point with extracellular ma
Externí odkaz:
https://doaj.org/article/3b313ae12f4c4ebbae078d91bb584ce4
Autor:
Michiru Otaki, Nozomi Hirane, Yayoi Natsume-Kitatani, Mari Nogami Itoh, Masanori Shindo, Yoichi Kurebayashi, Shin-Ichiro Nishimura
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract This study presents “mouse tissue glycome atlas” representing the profiles of major N-glycans of mouse glycoproteins that may define their essential functions in the surface glycocalyx of mouse organs/tissues and serum-derived extracellu
Externí odkaz:
https://doaj.org/article/5de9196a41814d5181581bf61c051185
Autor:
Abrha G. Gebrehiwot, Daniel Seifu Melka, Yimenashu Mamo Kassaye, Tufa Gemechu, Wajana Lako, Hiroshi Hinou, Shin-Ichiro Nishimura
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-18 (2019)
Abstract Background Alterations in protein glycosylation patterns have potentially been targeted for biomarker discovery in a wide range of diseases including cancer. Although there have been improvements in patient diagnosis and survival for breast
Externí odkaz:
https://doaj.org/article/0129004bc2234bdb9f7c75fe329cb3cd
Autor:
Shoichi Naito, Tatsuya Takahashi, Junji Onoda, Shoko Uemura, Naoki Ohyabu, Hiroshi Takemoto, Shoji Yamane, Ikuo Fujii, Shin-Ichiro Nishimura, Yoshito Numata
Publikováno v:
ACS Omega, Vol 2, Iss 11, Pp 7493-7505 (2017)
Externí odkaz:
https://doaj.org/article/5521e852b971454e9de4ff79fdc62d2b
Autor:
Lukas Heger, Silke Balk, Jennifer J. Lühr, Gordon F. Heidkamp, Christian H. K. Lehmann, Lukas Hatscher, Ariawan Purbojo, Arndt Hartmann, Fayna Garcia-Martin, Shin-Ichiro Nishimura, Robert Cesnjevar, Falk Nimmerjahn, Diana Dudziak
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Dendritic cells (DCs) are major players for the induction of immune responses. Apart from plasmacytoid DCs (pDCs), human DCs can be categorized into two types of conventional DCs: CD141+ DCs (cDC1) and CD1c+ DCs (cDC2). Defining uniquely expressed su
Externí odkaz:
https://doaj.org/article/8ffd0c96016f4660bb2bf458c976d932
Autor:
Abrha G Gebrehiwot, Daniel Seifu Melka, Yimenashu Mamo Kassaye, Ibrahim F Rehan, Shobith Rangappa, Hiroshi Hinou, Toshiya Kamiyama, Shin-Ichiro Nishimura
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209515 (2018)
BackgroundMost glycomics studies have focused on understanding disease mechanisms and proposing serum markers for various diseases, yet the influence of ethnic variation on the identified glyco-biomarker remains poorly addressed. This study aimed to
Externí odkaz:
https://doaj.org/article/dd18d0f9ddb143419eb0491cf549bd2b
Publikováno v:
Stem Cell Research, Vol 13, Iss 3, Pp 454-464 (2014)
Alterations in the structure of cell surface glycoforms occurring during the stages of stem cell differentiation remain unclear. We describe a rapid glycoblotting-based cellular glycomics method for quantitatively evaluating changes in glycoform expr
Externí odkaz:
https://doaj.org/article/0b3d7eca4d774a43bb05625b68b27dec
Publikováno v:
Sensors, Vol 8, Iss 7, Pp 4282-4295 (2008)
Carcinoembryonic antigen (CEA) is an oncofoetal cell-surface glycoprotein that serves as an important tumor marker for colorectal and some other carcinomas. In this work, a CEA immunoassay using a surface plasmon resonance (SPR) biosensor has been de
Externí odkaz:
https://doaj.org/article/e49afce2a20745e8987ae1bd26ab530d
Autor:
Koji Miyahara, Kazuhiro Nouso, Shunsuke Saito, Sakiko Hiraoka, Keita Harada, Sakuma Takahashi, Yuki Morimoto, Sayo Kobayashi, Fusao Ikeda, Yasuhiro Miyake, Hidenori Shiraha, Akinobu Takaki, Hiroyuki Okada, Maho Amano, Kazuko Hirose, Shin-Ichiro Nishimura, Kazuhide Yamamoto
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e74861 (2013)
BACKGROUND: The aims of this study were to determine the change of whole-serum N-glycan profile in ulcerative colitis (UC) patients and to investigate its clinical utility. METHODS: We collected serum from 75 UC patients at the time of admission and
Externí odkaz:
https://doaj.org/article/71a2f4ffec3840f8b72ba70ca6f6cbe5