Výsledky vyhledávání - "Shin Okuyama"

Induction of cellular senescence in fibroblasts through β1-integrin activation by tenascin-C-derived peptide and its protumor effect

Autor: Motomichi, Fujita, Manabu, Sasada, Mayu, Eguchi, Takuya, Iyoda, Shin, Okuyama, Takuro, Osawa, Kenta, Tsuzuranuki, Mamoru, Sakamoto, Yu, Hagihara, Masaki, Matsumura, Satoshi, Osada, Hiroaki, Kodama, Yoshikazu, Higami, Fumio, Fukai

Publikováno v: Am J Cancer Res

Tenascin-C is upregulated during inflammation and tumorigenesis, and its expression level is correlated with a poor prognosis in several malignancies. Nevertheless, the substantial role of tenascin-C in cancer progression is poorly understood. Previo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8a1b9c0b0bc43243af564f3b0c7a6647
https://europepmc.org/articles/PMC8493383/

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Evaluation of a newly proposed renal risk score for Japanese patients with ANCA-associated glomerulonephritis

Autor: Masaya Saito, Ayano Saito, Fumito Abe, Chihiro Imaizumi, Hajime Kaga, Masato Sawamura, Mizuho Nara, Masatoyo Ozawa, Ryuta Sato, Takahiro Nakayama, Shin Okuyama, Rie Masai, Hiroshi Ohtani, Atsushi Komatsuda, Hideki Wakui, Naoto Takahashi

Publikováno v: Clinical and experimental nephrology. 26(8)

We determined the usefulness and prognostic ability of the renal risk score (RRS), proposed in Europe, for Japanese patients with antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis (AAGN) and high myeloperoxidase (MPO)-ANCA posi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb6626844ffb048b52efad2f1156132
https://pubmed.ncbi.nlm.nih.gov/35394553

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Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis Complicated by Periaortitis and Cranial Hypertrophic Pachymeningitis: A Report of an Autopsy Case

Autor: Hajime Kaga, Mizuho Nara, Naoto Takahashi, Atsushi Komatsuda, Masaru Togashi, Ayumi Omokawa, Hideki Wakui, Masaya Saito, Shin Okuyama

Publikováno v: Internal Medicine

Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) is a systemic inflammatory disorder categorized as small-vessel vasculitis. We herein report an elderly Japanese man with AAV (granulomatosis with polyangiitis affecting the eyes, nose,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d05d1068b56c2b98391cff26e53b285
https://doi.org/10.2169/internalmedicine.8751-16

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Effect of CYP3A5 and ABCB1 polymorphisms on the interaction between tacrolimus and itraconazole in patients with connective tissue disease

Autor: Hideki Wakui, Mizuho Nara, Masatomo Miura, Maiko Abumiya, Masaru Togashi, Shin Okuyama, Naoto Takahashi, Atsushi Komatsuda, Takenori Niioka, Ayumi Omokawa

Publikováno v: European Journal of Clinical Pharmacology. 71:1091-1097

The aim of this study was to investigate the effect of itraconazole (ITCZ), a potent inhibitor of CYP3A4 and P-glycoprotein, on the blood concentration 12 h after tacrolimus administration (C 12h) in relation to CYP3A5 6986A>G and ABCB1 3435C>T genot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::626560496cf3a4c1f9142e291290a9d2
https://doi.org/10.1007/s00228-015-1901-4

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Analysis of PLA2R1 and HLA-DQA1 sequence variants in Japanese patients with idiopathic and secondary membranous nephropathy

Autor: Shin Okuyama, Hajime Kaga, Naoto Takahashi, Hideki Wakui, Ayumi Omokawa, Atsushi Komatsuda, Kensuke Mori

Publikováno v: Clinical and experimental nephrology. 22(2)

Several recent studies in patients with idiopathic membranous nephropathy (iMN) from Western and Asian counties showed that some single nucleotide polymorphisms (SNPs) within the PLA2R1 and HLA-DQA1 genes are significantly associated with iMN. Howeve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e1d8a155caf317fa60e16aa891964b0
https://pubmed.ncbi.nlm.nih.gov/28849274

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Quantification of Interstitial Fibrosis in Renal Allografts and Clinical Correlates of Long-Term Graft Function

Autor: Naoto Takahashi, Tomonori Habuchi, Shigeru Satoh, Takamitsu Inoue, Mitsuru Saito, Takenori Niioka, Mizuho Nara, Atsushi Komatsuda, Kazuyuki Numakura, Yoko Mitobe, Masatomo Miura, Shin Okuyama

Publikováno v: American journal of nephrology. 46(3)

Background: The present study investigated interstitial fibrosis (IF) in 144 kidney recipients 0 h and 1 year post transplantation and assessed relationships with Banff code scores, clinical parameters, and long-term graft function. Methods: A quanti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28dcea4d4fdb4ab8fb9e99b9fef13f1
https://pubmed.ncbi.nlm.nih.gov/28848141

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Clinicopathological and long-term prognostic features of membranous nephropathy with crescents: a Japanese single-center experience

Autor: Mizuho Nara, Fumito Abe, Shin Okuyama, Masaya Saito, Masato Sawamura, Ayano Saito, Masaru Togashi, Atsushi Komatsuda, Hajime Kaga, Hideki Wakui, Ryuta Sato, Naoto Takahashi

Publikováno v: Clinical and experimental nephrology. 22(2)

Three recent studies from the United States and China reported the clinicopathological features and short-term prognosis in patients with membranous nephropathy (MN) and crescents in the absence of secondary MN, anti-glomerular basement membrane (GBM

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a411d9450f5cf8905796ac18d5ec483b
https://pubmed.ncbi.nlm.nih.gov/28852884

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Validation of the 2010 histopathological classification of ANCA-associated glomerulonephritis in a Japanese single-center cohort

Autor: Ayumi Omokawa, Mizuho Nara, Atsushi Komatsuda, Hideki Wakui, Masaru Togashi, Kenichi Sawada, Shin Okuyama

Publikováno v: Modern Rheumatology. 24:300-303

OBJECTIVES: To validate the 2010 histopathological classification system of anti-neutrophil cytoplasmic antibodies (ANCA)-associated glomerulonephritis (GN) in a Japanese single-center cohort. METHODS: We retrospectively studied 54 patients (28 renal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f350185ba896868cd30902362f543969
https://doi.org/10.3109/14397595.2013.854068

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Serum interleukin 6 levels as a useful prognostic predictor of clinically amyopathic dermatomyositis with rapidly progressive interstitial lung disease

Autor: Kenichi Sawada, Shin Okuyama, Ayumi Omokawa, Atsushi Komatsuda, Hideki Wakui, Masaru Togashi, Mizuho Nara

Publikováno v: Modern Rheumatology. 24:633-636

Objectives Clinically amyopathic dermatomyositis (CADM) is considered as the subtype of dermatomyositis with amyopathy or hypomyopathy. Rapidly progressive interstitial lung disease (RP-ILD) is treatment-resistant and life-threatening in patients wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7458f6b0d8d36d8d83cefcb8b3a70abd
https://doi.org/10.3109/14397595.2013.844390

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