Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Shin Ogata"'
Autor:
Shin-ichiro Takebayashi, Tyrone Ryba, Kelsey Wimbish, Takuya Hayakawa, Morito Sakaue, Kenji Kuriya, Saori Takahashi, Shin Ogata, Ichiro Hiratani, Katsuzumi Okumura, Masaki Okano, Masato Ogata
Publikováno v:
Cells, Vol 10, Iss 2, p 266 (2021)
Multiple epigenetic pathways underlie the temporal order of DNA replication (replication timing) in the contexts of development and disease. DNA methylation by DNA methyltransferases (Dnmts) and downstream chromatin reorganization and transcriptional
Externí odkaz:
https://doaj.org/article/34deeb6edbe3441688a6f882879d3d02
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 82:2098-2100
Here, we show that semiconductor-based sequencing technology can be used to map mammalian replication domains, chromosomal units with similar DNA replication timing. Replicating DNA purified from mammalian cells was successfully sequenced by the Ion
Autor:
Masakazu Tanaka, Joel Moss, Masaki Tsukada, Shin Ogata, Teruaki Sato, Takayuki Eguchi, Sachiko Yamashita, Yoshisuke Nishi, Masanao Miwa, Susumu Ikegami, Chieri Ida, Takahiro Fujii
Publikováno v:
Analytical Biochemistry. 494:76-81
PolyADP-ribosylation is mediated by poly(ADP-ribose) (PAR) polymerases (PARPs) and may be involved in various cellular events, including chromosomal stability, DNA repair, transcription, cell death, and differentiation. The physiological level of PAR
Autor:
Shin Ogata, Eriko Avşar-Ban, Shin-ichiro Takebayashi, Masato Ogata, Kenji Kuriya, Eriko Higashiyama, Katsuzumi Okumura, Yutaka Tamaru, Kaede Hattori, Nanami Okochi
Publikováno v:
Bioscience, biotechnology, and biochemistry. 80(5)
We analyzed DNA replication in early zebrafish embryos. The replicating DNA of whole embryos was labeled with the thymidine analog 5-ethynyl-2ʹ-deoxyuridine (EdU), and spatial regulation of replication sites was visualized in single embryo-derived c
Publikováno v:
Process Biochemistry. 45:54-59
Poly(ADP-ribosyl)ation, synthesized mainly by poly(ADP-ribose) polymerase-1 (PARP-1) using nicotinamide adenine dinucleotide as a substrate, has been identified as a post-translational modification of nuclear proteins in many eukaryotic cells. At pre
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 73:79-84
Nicotinic acid and nicotinamide belong to the water-soluble vitamins, and they have many physiological and pharmacological functions in various organisms. In this study, we investigated the differentiation-inducing ability of nicotinic acid-related c
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 72:868-871
Changes in gene expression levels of c-myc and CD38 were examined during the differentiation of HL-60 cells to granulocytes due to three nicotinic acid-related compounds. CD38 expression was increased by isonicotinic acid and all-trans-retinoic acid
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 71:627-632
Fluorescence in situ hybridization (FISH) is a useful method of determining the replication timing of specific genomic loci in mammals and of delineating replicon structures on DNA fibers in combination with in vivo replication labeling. In the case
Autor:
Yutaka Tamaru, Kenji Kuriya, Masato Ogata, Shin-ichiro Takebayashi, Eriko Higashiyama, Katsuzumi Okumura, Shin Ogata, Eriko Avşar-Ban
Publikováno v:
Zebrafish. 12(6)
Spatiotemporal regulation of DNA replication in the S-phase nucleus has been extensively studied in mammalian cells because it is tightly coupled with the regulation of other nuclear processes such as transcription. However, little is known about the
Publikováno v:
CYTOLOGIA. 70:59-64
Our aim is to develop and evaluate monitoring systems using aquatic organisms to assess the genotoxicity of water. We evaluated the genotoxicity of 5 model chemical mutagens by single cell gel electrophoresis (comet assay) using goldfish primary cult