Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Shin Nosuke Uno"'
Autor:
Katsuhiro Murakami, Amane Harada, Ryuji Toh, Takuya Kubo, Keiko Miwa, Jeeeun Kim, Maria Kiriyama, Takuya Iino, Youichi Nishikawa, Shin-Nosuke Uno, Kohei Akatsuchi, Manabu Nagao, Tatsuro Ishida, Ken-ichi Hirata
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract High-density lipoprotein (HDL) cholesterol efflux capacity (CEC), which is a conventional metric of HDL function, has been associated with coronary heart disease risk. However, the CEC assay requires cultured cells and takes several days to
Externí odkaz:
https://doaj.org/article/1de9aa4def1445c6b15847a2a21ee1b1
Autor:
Masatoshi Suganuma, Masaya Okada, Yuji Kazuta, Kazuto Yamashita, Shingo Fujiyama, Takafumi Motoki, Hiroyuki Amino, Yuki Shimaoka, Yoshihiko Norimine, Daiki Hara, Youichi Nishikawa, Shigeki Iwanaga, Shin-nosuke Uno
Publikováno v:
The Journal of Physical Chemistry B. 125:8703-8711
Single-molecule localization microscopy (SMLM) enables the visualization of biomolecules at unprecedented resolution and requires control of the fluorescent blinking (ON/OFF) states of fluorophores to detect single-molecule fluorescence without overl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53dfb2f2202d3b0ac23a6af83ba2bd69
https://doi.org/10.1021/acs.jpcb.1c03193
https://doi.org/10.1021/acs.jpcb.1c03193
Autor:
Yoshiaki Iwadate, Chika Okimura, Yasuteru Urano, Kaoru Sugimura, Yusuke Nomura, Kenjiro Hanaoka, Toru Komatsu, Shin-nosuke Uno, Tasuku Ueno, Tetsuo Nagano, Keisuke Ikawa, Takeru Takagi, Mako Kamiya, Kenzo Hirose, Daisuke Asanuma
Publikováno v:
Science Advances
Description
We found an F-actin–binding small molecule serving as a fluorescent probe and a scaffold for functional probes.
Actin is a ubiquitous cytoskeletal protein, forming a dynamic network that generates mechanical forces in the cell
We found an F-actin–binding small molecule serving as a fluorescent probe and a scaffold for functional probes.
Actin is a ubiquitous cytoskeletal protein, forming a dynamic network that generates mechanical forces in the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b1ffaa9b9a73dcecee3bd4d9c75c6c
https://pubmed.ncbi.nlm.nih.gov/34797716
https://pubmed.ncbi.nlm.nih.gov/34797716
Publikováno v:
Single Molecule Spectroscopy and Superresolution Imaging XIV.
Abnormal deposition of amyloid-β (Aβ) causes the formation of senile plaques, which is one of the main pathological features of Alzheimer disease. To visualize the plaques at nanometer resolution, single-molecule localization microscopy (SMLM) is p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::720f9e7e713579ee7f0801c2357dcd2d
https://doi.org/10.1117/12.2578140
https://doi.org/10.1117/12.2578140
Autor:
Ryosuke Kojima, Yasuteru Urano, Mako Kamiya, Shin-nosuke Uno, Seiji Tobita, Akihiko Morozumi, Keitaro Umezawa, Toshitada Yoshihara
Publikováno v:
Journal of the American Chemical Society.
Single-molecule localization microscopy (SMLM) allows the reconstruction of super-resolution images but generally requires prior intense laser irradiation and in some cases additives to induce blinking of conventional fluorophores. We previously intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ce17f6e1645a9df8e5a3d73d0a8a7d
https://doi.org/10.1021/jacs.0c00451
https://doi.org/10.1021/jacs.0c00451
Autor:
Yoshiaki Iwadate, Kenzo Hirose, Daisuke Asanuma, Mako Kamiya, Toru Komatsu, Kaoru Sugimura, Yasuteru Urano, Takeru Takagi, Tasuku Ueno, Shin-nosuke Uno, Keisuke Ikawa, Tetsuo Nagano, Kenjiro Hanaoka, Chika Okimura, Yusuke Nomura
Actin is a ubiquitous cytoskeletal protein, forming a dynamic network that generates mechanical forces in the cell. Here, in order to dissect the complex mechanisms of actin-related cellular functions, we introduce two powerful tools based on a new c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5abf5dc9694b121b3d295a52ecea3e4a
https://doi.org/10.26434/chemrxiv.12272024
https://doi.org/10.26434/chemrxiv.12272024
Autor:
Kai Johnsson, Mako Kamiya, Ryosuke Kojima, Yasuteru Urano, Shin-nosuke Uno, Hiroyoshi Fujioka
Publikováno v:
Chemical Communications
We show that the equilibrium of intramolecular spirocyclization of coumarin-hemicyanine hybrid fluorophores can be finely tuned by means of chemical modifications. We used this scaffold to develop activatable fluorescent probes with large Stokes shif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1aa5236c8d99eebc4823104aa4afe9
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100891034
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100891034
Autor:
Shin Nosuke Uno, Mako Kamiya, Akari Shimauchi, Kei Sukenobe, Toru Kondo, Michio Matsushita, Satoru Fujiyoshi, M. Hirano, Yasuteru Urano, Hiroaki Tabe, Atsunori Sakurai, Minako Maruo
Publikováno v:
The Journal of Physical Chemistry B. 122:6906-6911
We prepared a pair with a visible-absorbing donor dye and a near-infrared fluorescing acceptor dye. The donor and the acceptor were covalently linked close enough for Förster resonance energy transfer to occur. Under cryogenic conditions at 1.7 K, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3285a4918dfc884dd120d60cc3973d
https://doi.org/10.1021/acs.jpcb.8b03977
https://doi.org/10.1021/acs.jpcb.8b03977
Publikováno v:
Chemical Communications. 54:102-105
We have developed the first green-light-emitting, spontaneously blinking fluorophore (SBF), HEtetTFER. In combination with our near-infrared-light-emitting SBF (HMSiR), HEtetTFER allows dual-colour single-molecule localization microscopy (SMLM) in bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26df567bccb87fa1403684d1201d70c
https://doi.org/10.1039/c7cc07783a
https://doi.org/10.1039/c7cc07783a
Autor:
Hideo Takakura, Derek Toomre, Felix Rivera-Molina, Alexander D. Thompson, Shin-nosuke Uno, Mako Kamiya, Joerg Bewersdorf, Alanna Schepartz, Yongdeng Zhang, Yasuteru Urano, Roman S. Erdmann, Brian McNellis, Yu Lin, James E. Rothman
Publikováno v:
Nature Biotechnology. 35:773-780
Imaging cellular structures and organelles in living cells by long time-lapse super-resolution microscopy is challenging, as it requires dense labeling, bright and highly photostable dyes, and non-toxic conditions. We introduce a set of high-density,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084fbb4ad34437a47d45eb5c6c12cf4f
https://doi.org/10.1038/nbt.3876
https://doi.org/10.1038/nbt.3876