Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Shin Nishiumi"'
Publikováno v:
Fermentation, Vol 9, Iss 3, p 300 (2023)
Obesity, along with hypertension and hyperlipidemia, is one of the leading factors of metabolic syndrome, which increases the risk of diabetes. However, controlling obesity is a global challenge. Sake lees, or Japanese rice wine lees, is a by-product
Externí odkaz:
https://doaj.org/article/b41029e7025c414fbe9bc48b4675d668
Autor:
Géraldine Luis, Adrien Godfroid, Shin Nishiumi, Jonathan Cimino, Silvia Blacher, Erik Maquoi, Coline Wery, Alice Collignon, Rémi Longuespée, Laetitia Montero-Ruiz, Isabelle Dassoul, Naima Maloujahmoum, Charles Pottier, Gabriel Mazzucchelli, Edwin Depauw, Akeila Bellahcène, Masaru Yoshida, Agnès Noel, Nor Eddine Sounni
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 102006- (2021)
Problem: Tumor recurrence is a major clinical issue that represents the principal cause of cancer-related deaths, with few targetable common pathways. Mechanisms by which residual tumors persist and progress under a continuous shift between hypoxia-r
Externí odkaz:
https://doaj.org/article/3eb5ddbabbf94bec843e6e8d4acb98c3
Autor:
Shin Nishiumi, Yoshihiro Izumi, Akiyoshi Hirayama, Masatomo Takahashi, Motonao Nakao, Kosuke Hata, Daisuke Saigusa, Eiji Hishinuma, Naomi Matsukawa, Suzumi M. Tokuoka, Yoshihiro Kita, Fumie Hamano, Nobuyuki Okahashi, Kazutaka Ikeda, Hiroki Nakanishi, Kosuke Saito, Masami Yokota Hirai, Masaru Yoshida, Yoshiya Oda, Fumio Matsuda, Takeshi Bamba
Publikováno v:
Metabolites, Vol 12, Iss 2, p 135 (2022)
In mass spectrometry-based metabolomics, the differences in the analytical results from different laboratories/machines are an issue to be considered because various types of machines are used in each laboratory. Moreover, the analytical methods are
Externí odkaz:
https://doaj.org/article/8145885c47ea46799181ed43e06d661b
Autor:
Takashi Nakanishi, Hirokazu Fukui, Xuan Wang, Shin Nishiumi, Haruka Yokota, Yutaka Makizaki, Yoshiki Tanaka, Hiroshi Ohno, Toshihiko Tomita, Tadayuki Oshima, Hiroto Miwa
Publikováno v:
Cells, Vol 10, Iss 11, p 3168 (2021)
Although high-fat diet (HFD)-related dysbiosis is involved in the development of steatohepatitis, its pathophysiology especially in the small intestine remains unclear. We comprehensively investigated not only the liver pathology but also the microbi
Externí odkaz:
https://doaj.org/article/f048463681c14ac89cf39d525ccd77fb
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-21 (2017)
Abstract Background Triple-negative breast cancer (TN) is more aggressive than other subtypes of breast cancer and has a lower survival rate. Furthermore, detailed biological information about the disease is lacking. This study investigated character
Externí odkaz:
https://doaj.org/article/46ac3e0468764ba5ab2ccc8334b9fad3
Autor:
Hirofumi Ogawa, Akira Iwamoto, Toshihito Tanahashi, Rina Okada, Koji Yamamoto, Shin Nishiumi, Masaru Yoshida, Takeshi Azuma
Publikováno v:
Gut Pathogens, Vol 9, Iss 1, Pp 1-12 (2017)
Abstract Background Helicobacter pylori infection is associated with risk for chronic gastritis (CG), gastric ulcer (GU), duodenal ulcer (DU), and gastric cancer (GC). The H. pylori Cag type IV secretion system (TFSS) translocates the virulence facto
Externí odkaz:
https://doaj.org/article/6e0eaaf4d5ac4dcfaa1e1e2fe5a03ab3
Autor:
Yu Sato, Takashi Kobayashi, Shin Nishiumi, Akihiko Okada, Tsuyoshi Fujita, Tsuyoshi Sanuki, Masao Kobayashi, Masakyo Asahara, Masayasu Adachi, Arata Sakai, Hideyuki Shiomi, Atsuhiro Masuda, Masaru Yoshida, Keiko Takeuchi, Yuzo Kodama, Hiromu Kutsumi, Kengo Nagashima, Kazufumi Honda
Publikováno v:
Cancers, Vol 12, Iss 9, p 2625 (2020)
Apolipoprotein A2-ATQ/AT (apoA2-ATQ/AT) has been identified as a minimally invasive biomarker for detecting pancreatic cancer (PC) and high-risk (HR) individuals for PC. To establish an efficient enrichment strategy for HR, we carried out a plasma ap
Externí odkaz:
https://doaj.org/article/d4fa30fc781941c4a7f3fc5ec7b96c90
Autor:
Shin Nishiumi, Makoto Suzuki, Takashi Kobayashi, Atsuki Matsubara, Takeshi Azuma, Masaru Yoshida
Publikováno v:
Metabolites, Vol 4, Iss 3, Pp 547-571 (2014)
The study of the omics cascade, which involves comprehensive investigations based on genomics, transcriptomics, proteomics, metabolomics, etc., has developed rapidly and now plays an important role in life science research. Among such analyses, metab
Externí odkaz:
https://doaj.org/article/5e34a92556ec4d589062497303d7f401
Autor:
Takeshi Azuma, Hiromi Yoshida, Masaru Yoshida, Isoko Kuriyama, Kazunori Tsubaki, Yasuyuki Kondo, Kazuyuki Nishio, Kouji Kuramochi, Shin Nishiumi, Masayuki Nishida, Yasuhiro Irino, Yoshiyuki Mizushina, Jun Maeda
Publikováno v:
International Journal of Molecular Sciences, Vol 12, Iss 2, Pp 1115-1132 (2011)
Previously, we reported that vitamin K3 (VK3), but not VK1 or VK2 (=MK-4), inhibits the activity of human DNA polymerase γ (pol γ). In this study, we chemically synthesized three intermediate compounds between VK2 and VK3, namely MK-3, MK-2 and MK-
Externí odkaz:
https://doaj.org/article/1d089ca4132f4b4e8a7f68fcbaf80f89
Autor:
Yutaka Fujiwara, Takashi Kobayashi, Naoko Chayahara, Yoshinori Imamura, Masanori Toyoda, Naomi Kiyota, Toru Mukohara, Shin Nishiumi, Takeshi Azuma, Masaru Yoshida, Hironobu Minami
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113259 (2014)
Cancer cachexia is a multifactorial syndrome characterized by progressive loss of weight and muscle atrophy. Using metabolomics, we investigated serum markers and their intra-day variation in advanced pancreatic cancer patients with cachexia.Patients
Externí odkaz:
https://doaj.org/article/8071ee0bdc66431c914808ce05f8cc71