Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shin Ichi Takemura"'
Autor:
Kouhei Tsumoto, Toshio Kudo, Shin Ichi Takemura, Hisaaki Saeki, Seiki Matsuno, Yu Katayose, Shinji Ebara, Hiroshi Yoshida, Naoki Sakurai, Masanori Suzuki, Ryutaro Asano, Hideaki Kodama, Izumi Kumagai, Kohzoh Imai
Publikováno v:
Cancer Immunology, Immunotherapy. 51:33-44
In cancer immunotherapy research, many bispecific antibodies (BsAbs) have been developed for directing T cells toward tumor cells. Recent advances in genetic engineering have made it possible to prepare immunoglobulin fragments consisting of variable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1bcbdd755774ebdcaa565933c4b6a0
https://doi.org/10.1007/s00262-001-0245-3
https://doi.org/10.1007/s00262-001-0245-3
Autor:
Masao Shinoda, Ryutaro Asano, Kohzoh Imai, Shinji Ebara, Izumi Kumagai, Naoki Sakurai, Seiki Matsuno, Toshio Kudo, Masanori Suzuki, Shin Ichi Takemura, Kouhei Tsumoto, Yu Katayose, Atsushi Teramae
Publikováno v:
Journal of Biochemistry. 127:673-679
A bacterial expression system for the variable region fragments (Fvs) of the anti-MUC1 tumor antigen antibody MUSE11 has been constructed. The Fv fragment showed binding specificity toward TFK-1 cells, with slightly reduced affinity compared to its p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0deedc4d0c07365236a6b48c9533cd7a
https://doi.org/10.1093/oxfordjournals.jbchem.a022656
https://doi.org/10.1093/oxfordjournals.jbchem.a022656
Autor:
Kouhei Tsumoto, Masanori Suzuki, Michiaki Unno, Izumi Kumagai, Ryutaro Asano, Hiroshi Yoshida, Hideaki Kodama, Seiki Matsuno, Hiroki Hayashi, Koki Makabe, Toshio Kudo, Kohzoh Imai, Shin Ichi Takemura, Yu Katayose
Publikováno v:
Cancer immunology, immunotherapy : CII. 53(6)
In the field of cancer immunotherapy research, the targeting of effector cells with specific antibodies is a very promising approach. Recent advances in genetic engineering have made it possible to prepare immunoglobulin fragments consisting of varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0692ad3d4cdcc94673ee59817d56cd3f
https://pubmed.ncbi.nlm.nih.gov/14648071
https://pubmed.ncbi.nlm.nih.gov/14648071
Autor:
Naoki Sakurai, Ryutaro Asano, Hideaki Kodama, Hisaaki Saeki, Toshio Kudo, Masao Shinoda, Masahiko Ichiyama, Kohzoh Imai, Masanori Suzuki, Hiroshi Yoshida, Yuji Hinoda, Seiki Matsuno, Shin Ichi Takemura, Yu Katayose
Publikováno v:
Immunology letters. 81(2)
For the purpose of establishing a new adoptive immunotherapy for bile duct carcinoma (BDC), we previously constructed two kinds of bispecific antibodies (bsAbs), anti-MUC1 x anti-CD3 (M x 3) and anti-MUC1 x anti-CD28 (M x 28), which activate T cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3a6f13308272b08a1b9e7df3f0d09f
https://pubmed.ncbi.nlm.nih.gov/11852114
https://pubmed.ncbi.nlm.nih.gov/11852114
Autor:
Kohei Tsumoto, Seiki Matsuno, Izumi Kumagai, Naoki Sakurai, Hiroshi Yoshida, Hisaaki Saeki, Ryutaro Asano, Shin Ichi Takemura, Masao Shinoda, Toshio Kudo, Yuji Hinoda, Hideaki Kodama, Yu Katayose, Masanori Suzuki, Masahiko Ichiyama, Kohzoh Imai
Publikováno v:
Cancer immunology, immunotherapy : CII. 50(10)
For the purpose of establishing a new adoptive immunotherapy for bile duct carcinoma (BDC), we have directed our attention to superantigens (SAgs), the most potent known activators of T lymphocytes. In our previous study, staphylococcal enterotoxin A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9031ff439af209d2d66b7c7d15959c
https://pubmed.ncbi.nlm.nih.gov/11776376
https://pubmed.ncbi.nlm.nih.gov/11776376
Autor:
Naoki Sakurai, Izumi Kumagai, Toshio Kudo, Ryutaro Asano, Hiroshi Yoshida, Kohzoh Imai, Kouhei Tsumoto, Shin Ichi Takemura, Yu Katayose, Seiki Matsuno, Shinji Ebara, Hideaki Kodama, Masanori Suzuki
Publikováno v:
Protein engineering. 13(8)
Diabodies are the recombinant bispecific antibodies (BsAbs), constructed from heterogeneous single-chain antibodies. Usually, diabodies have been prepared from bacterial periplasmic fraction using a co-expression vector (i.e. genes encoding two chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9ab3297f53fdfb85fe9b3f15e226ff
https://pubmed.ncbi.nlm.nih.gov/10964988
https://pubmed.ncbi.nlm.nih.gov/10964988
Autor:
Toshio Kudo, Ryutaro Asano, Shin Ichi Takemura, Takashi Arai, Yu Katayose, Naoki Sakurai, Hiroshi Yoshida, Hideaki Kodama, Seiki Matsuno, Izumi Kumagai, Masanori Suzuki, Kouhei Tsumoto
Publikováno v:
FEBS letters. 476(3)
The most predominant co-stimulation pathway, which is critical for T cell activation and proliferation, is the CD28-B7 pathway. The anti-CD28 monoclonal antibody (mAb) also provides a co-stimulatory signal to T cells. In order to construct a function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819ce9641270e5d0a31287da7d66ce39
https://pubmed.ncbi.nlm.nih.gov/10913626
https://pubmed.ncbi.nlm.nih.gov/10913626
Solid Surface Enhancement Effects on Chemiluminescence: Influence of Cationic Species in Solid Media
Autor:
Tetsutaro Yoshinaga, Hiroshi Hiratsuka, Miki Hasegawa, Shin-Ichi Takemura, Michio Kobayashi, Shigekazu Akimoto, Toshihiko Hoshi
Publikováno v:
Chemistry Letters. 32:102-103
Solid surface enhancement effects on chemiluminescence (CL) have been studied using metal salicylates as solid media. Interesting CL characteristics depending on kinds of cationic species (alkaline metal ions, alkaline earth metal ions etc.) on chemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41ad665e99edb68c5e7d1df6340b0750
https://doi.org/10.1246/cl.2003.102
https://doi.org/10.1246/cl.2003.102
Autor:
Izumi Kumagai, Naoki Sakurai, Toshio Kudo, Tadashi Kurokawa, Atsushi Teramae, Yuji Hinoda, Shinji Ebara, Hideaki Kodama, Masao Shinoda, Seiki Matsuno, Kouhei Tsumoto, Masanori Suzuki, Shin Ichi Takemura, Yu Katayose, Kohzoh Imai
Publikováno v:
Biochemical and Biophysical Research Communications. 259:230
A SEA-antibody single chain Fv (SEA-scFv) fusion protein was produced by bacterial expression system in this study. SEA-scFv has both staphylococcal enterotoxin A (SEA) effects and antibody activity directed at the epithelial mucin core protein MUC1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df9a9cc167e25b30b8eb8c50e12d0f52
https://doi.org/10.1006/bbrc.1999.0756
https://doi.org/10.1006/bbrc.1999.0756