Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Shin H Kang"'
Autor:
Estibaliz González-Fernández, Hey-Kyeong Jeong, Masahiro Fukaya, Hyukmin Kim, Rabia R Khawaja, Isha N Srivastava, Ari Waisman, Young-Jin Son, Shin H Kang
Publikováno v:
eLife, Vol 7 (2018)
Oligodendrocytes (OLs), the myelin-forming CNS glia, are highly vulnerable to cellular stresses, and a severe myelin loss underlies numerous CNS disorders. Expedited OL regeneration may prevent further axonal damage and facilitate functional CNS repa
Externí odkaz:
https://doaj.org/article/25592acd46534d9e8433fff4b88321ed
Autor:
Matthew Grove, Hyukmin Kim, Maryline Santerre, Alexander J Krupka, Seung Baek Han, Jinbin Zhai, Jennifer Y Cho, Raehee Park, Michele Harris, Seonhee Kim, Bassel E Sawaya, Shin H Kang, Mary F Barbe, Seo-Hee Cho, Michel A Lemay, Young-Jin Son
Publikováno v:
eLife, Vol 6 (2017)
Nuclear exclusion of the transcriptional regulators and potent oncoproteins, YAP/TAZ, is considered necessary for adult tissue homeostasis. Here we show that nuclear YAP/TAZ are essential regulators of peripheral nerve development and myelin maintena
Externí odkaz:
https://doaj.org/article/eae26989c1b34d3cb0582278302e9660
Autor:
Hyukmin Kim, Andy Skuba, Jingsheng Xia, Sung Baek Han, Jinbin Zhai, Huijuan Hu, Shin H. Kang, Young-Jin Son
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113068- (2023)
Summary: Primary somatosensory axons stop regenerating as they re-enter the spinal cord, resulting in incurable sensory loss. What arrests them has remained unclear. We previously showed that axons stop by forming synaptic contacts with unknown non-n
Externí odkaz:
https://doaj.org/article/617f26c30b874e21a082fbab7ef1c13b
GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration
Autor:
Rabia R. Khawaja, Amit Agarwal, Masahiro Fukaya, Hey-Kyeong Jeong, Scott Gross, Estibaliz Gonzalez-Fernandez, Jonathan Soboloff, Dwight E. Bergles, Shin H. Kang
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109147- (2021)
Summary: Oligodendrocyte precursor cells (OPCs) are essential for developmental myelination and oligodendrocyte regeneration after CNS injury. These progenitors express calcium-permeable AMPA receptors (AMPARs) and form direct synapses with neurons t
Externí odkaz:
https://doaj.org/article/c6a1455b301e42c6970b60b10b9ef2bc
Autor:
Hyukmin Kim, Andy Skuba, Jingsheng Xia, Sung Baek Han, Jinbin Zhai, Huijuan Hu, Shin H. Kang, Young-Jin Son
Primary sensory axons stop regenerating as they enter the spinal cord, resulting in incurable sensory loss. What arrests them remains unknown. We previously showed that axons stop by forming synaptic contacts with unknown non-neuronal cells. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de7c812cc51e58619793c6ba99d9b382
https://doi.org/10.1101/2022.09.28.509944
https://doi.org/10.1101/2022.09.28.509944
Publikováno v:
Frontiers in Cellular Neuroscience. 16
Oligodendrocytes (OLs) form myelin sheaths and provide metabolic support to axons in the CNS. Although most OLs develop during early postnatal life, OL generation continues in adulthood, and this late oligodendrogenesis may contribute to neuronal net
GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration
Autor:
Amit Agarwal, Dwight E. Bergles, Shin H. Kang, Scott Gross, Rabia R. Khawaja, Masahiro Fukaya, Hey-Kyeong Jeong, Estibaliz González-Fernández, Jonathan Soboloff
Publikováno v:
Cell Reports, Vol 35, Iss 7, Pp 109147-(2021)
Cell reports
Cell reports
SUMMARY Oligodendrocyte precursor cells (OPCs) are essential for developmental myelination and oligodendrocyte regeneration after CNS injury. These progenitors express calcium-permeable AMPA receptors (AMPARs) and form direct synapses with neurons th
Autor:
Hyukmin Kim, Estibaliz González-Fernández, Ari Waisman, Isha N Srivastava, Young-Jin Son, Masahiro Fukaya, Rabia R. Khawaja, Hey-Kyeong Jeong, Shin H. Kang
Publikováno v:
eLife, Vol 7 (2018)
Oligodendrocytes (OLs), the myelin-forming CNS glia, are highly vulnerable to cellular stresses, and a severe myelin loss underlies numerous CNS disorders. Expedited OL regeneration may prevent further axonal damage and facilitate functional CNS repa
Autor:
Ari Waisman, Hey-Kyeong Jeong, Rabia R. Khawaja, Shin H. Kang, Masahiro Fukaya, Young-Jin Son, Hyukmin Kim, Estibaliz González-Fernández, Isha N Srivastava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71226721914ad5259073b1dc165cae4a
https://doi.org/10.7554/elife.32021.040
https://doi.org/10.7554/elife.32021.040
Autor:
C. James Howell, Seong Il Lee, Sarah A. Busch, Amanda Phuong Tran, Shin H. Kang, Joel M. Levine, Teresa A. Evans, Jerry Silver, William B. Stallcup, Dwight E. Bergles, Angela R. Filous
Publikováno v:
The Journal of Neuroscience. 34:16369-16384
NG2 is purportedly one of the most growth-inhibitory chondroitin sulfate proteoglycans (CSPGs) produced after spinal cord injury. Nonetheless, once the severed axon tips dieback from the lesion core into the penumbra they closely associate with NG2+