Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Shin‐ichiro Yoshimura"'
Autor:
Akihiro Harada, Masataka Kunii, Kazuo Kurokawa, Takuya Sumi, Satoshi Kanda, Yu Zhang, Satomi Nadanaka, Koichiro M. Hirosawa, Kazuaki Tokunaga, Takuro Tojima, Manabu Taniguchi, Kenta Moriwaki, Shin-ichiro Yoshimura, Miki Yamamoto-Hino, Satoshi Goto, Toyomasa Katagiri, Satoshi Kume, Mitsuko Hayashi-Nishino, Miyako Nakano, Eiji Miyoshi, Kenichi G. N. Suzuki, Hiroshi Kitagawa, Akihiko Nakano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Knowledge on the distribution and dynamics of glycosylation enzymes in the Golgi is essential for better understanding this modification. Here, using a combination of CRISPR/Cas9 knockin technology and super-resolution microscopy, we show th
Externí odkaz:
https://doaj.org/article/fd8fce91b1f74602a6b152cacc39ff8a
Autor:
Yukako Oe, Keita Kakuda, Shin-Ichiro Yoshimura, Naohiro Hara, Junya Hasegawa, Seigo Terawaki, Yasuyoshi Kimura, Kensuke Ikenaka, Shiro Suetsugu, Hideki Mochizuki, Tamotsu Yoshimori, Shuhei Nakamura
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010264 (2022)
Autophagy is an indispensable process that degrades cytoplasmic materials to maintain cellular homeostasis. During autophagy, double-membrane autophagosomes surround cytoplasmic materials and either fuse with endosomes (called amphisomes) and then ly
Externí odkaz:
https://doaj.org/article/50ae2e2999ad4446803a96263e7e291f
Autor:
Ryo Higaki, Aya Miyazaki, Yujiro Tajiri, Mikihito Shoji, Shun Saito, Shin-ichiro Yoshimura, Naoki Miki, Kazuhiro Hatta, Hiraku Doi
Publikováno v:
Journal of Medical Case Reports, Vol 12, Iss 1, Pp 1-4 (2018)
Abstract Background Takayasu’s arteritis is extremely rare in children aged below 6 years. At the onset of Takayasu’s arteritis in children, symptoms are varied but differ from those in adults. Corticosteroids are the mainstay of treatment for pr
Externí odkaz:
https://doaj.org/article/77eb170c328043fdbc98236240359173
Autor:
Tomoaki Sobajima, Shin-ichiro Yoshimura, Tomohiko Iwano, Masataka Kunii, Masahiko Watanabe, Nur Atik, Sotaro Mushiake, Eiichi Morii, Yoshihisa Koyama, Eiji Miyoshi, Akihiro Harada
Publikováno v:
Biology Open, Vol 4, Iss 1, Pp 86-94 (2014)
The small GTPase Rab11 plays an important role in the recycling of proteins to the plasma membrane as well as in polarised transport in epithelial cells and neurons. We generated conditional knockout mice deficient in Rab11a. Rab11a-deficient mice ar
Externí odkaz:
https://doaj.org/article/94b9242d6fd3498883c7f34bd477c111
Autor:
Jia-Jie Teoh, Tomohiko Iwano, Masataka Kunii, Nur Atik, Erda Avriyanti, Shin-Ichiro Yoshimura, Kenta Moriwaki, Akihiro Harada
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175888 (2017)
BIG1, an activator protein of the small GTPase, Arf, and encoded by the Arfgef1 gene, is one of candidate genes for epileptic encephalopathy. To know the involvement of BIG1 in epileptic encephalopathy, we analyzed BIG1-deficient mice and found that
Externí odkaz:
https://doaj.org/article/1f8315668cb944e98e10ee25a59f1ab9
Publikováno v:
Journal of Neuroscience; 7/3/2024, Vol. 44 Issue 27, p1-20, 20p
Autor:
Ji Wu, Kenta Moriwaki, Tatsuya Asuka, Ritsuko Nakai, Satoshi Kanda, Manabu Taniguchi, Tatsuki Sugiyama, Shin-ichiro Yoshimura, Masataka Kunii, Takashi Nagasawa, Naoki Hosen, Eiji Miyoshi, Akihiro Harada
Publikováno v:
Blood Advances.
Cell polarity, the asymmetric distribution of proteins and organelles, is permanently or transiently established in various cell types and plays an important role in many physiological events. EH domain-binding protein 1 like 1 (EHBP1L1) is an adapto
Autor:
Kohei Tsujimoto, Tatsunori Jo, Daiki Nagira, Hachiro Konaka, Jeong Hoon Park, Shin‐ichiro Yoshimura, Akinori Ninomiya, Fuminori Sugihara, Takehiro Hirayama, Eri Itotagawa, Yusei Matsuzaki, Yuki Takaichi, Wataru Aoki, Shotaro Saita, Shuhei Nakamura, Andrea Ballabio, Shigeyuki Nada, Masato Okada, Hyota Takamatsu, Atsushi Kumanogoh
The cellular activation of the NLRP3 inflammasome is spatiotemporally orchestrated by various organelles, but whether lysosomes contribute to this process remains unclear. Here, we show the vital role of the lysosomal membrane-tethered Ragulator comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04657f2a72b81ed0d935697098ec1e17
https://hdl.handle.net/11588/906504
https://hdl.handle.net/11588/906504
Publikováno v:
Journal of Biological Chemistry. 299:102985
Autor:
Shin-ichiro Yoshimura, Ken Sato, Yuria Noguchi, Masaharu Ogawa, Tomohiko Iwano, Masataka Kunii, Takashi Sato, Akihiro Harada, Erda Avriyanti, Nur Atik, Satoshi Kanda
Publikováno v:
The Journal of Cell Biology
Kunii et al. show that neuron-specific SNAP23 knockout mice lack a hippocampus and cerebellum. The SNAP23–VAMP8–Syntaxin1B complex mediates the apical localization of N-cadherin, which is essential for the formation of apical junctional complexes