Zobrazeno 1 - 10
of 280
pro vyhledávání: '"Shin‐Yup Lee"'
Autor:
Da Som Jeon, Cheol‐kyu Park, Seung Joon Kim, Chan Kwon Park, Yoon Soo Chang, Chi Young Jung, Sung Yong Lee, Shin‐Yup Lee, Jeong‐Seon Ryu, Jeong Eun Lee, Kye Young Lee, Tae Won Jang, Seung Hun Jang, Seong Hoon Yoon, Sang Hoon Lee, Chang‐min Choi, Hyeong Ryul Kim, Yeon Joo Kim
Publikováno v:
Thoracic Cancer, Vol 15, Iss 6, Pp 448-457 (2024)
Abstract Background About 3%–5% of non‐small cell lung cancer (NSCLC) presents positive anaplastic lymphoma kinase (ALK). Recently, several target agents have been approved as a treatment for ALK‐positive NSCLC. This study aimed to analyze the
Externí odkaz:
https://doaj.org/article/2f6fe30c7c754b55b863f231b24d86f8
Autor:
Jun-Kyu Byun, Yeon-Kyung Choi, Ji-Hyun Kim, Ji Yun Jeong, Hui-Jeon Jeon, Mi-Kyung Kim, Ilseon Hwang, Shin-Yup Lee, You Mie Lee, In-Kyu Lee, Keun-Gyu Park
Publikováno v:
Cell Reports, Vol 20, Iss 3, Pp 586-599 (2017)
Proper regulation of mTORC1 and mTORC2 upon nutrient starvation is critical for cancer cell survival. Upregulation of Sestrin2 in response to glutamine deprivation rescues cell death by suppressing mTORC1. However, the contribution of mTORC2 to Sestr
Externí odkaz:
https://doaj.org/article/9515e654db7b4ff09beddd5322bcf9dd
Autor:
Jehun Kim, Taeyun Kim, Tae Won Jang, Hee Kang, Mi Hyun Kim, Seong Hoon Yoon, Choon‐Hee Son, Hyun‐Kyung Lee, Hyun‐Kuk Kim, Shin Yup Lee, Kyeong Choel Shin, Ji‐Yeon Han, Eun‐Ju Kang
Publikováno v:
Thoracic Cancer, Vol 13, Iss 15, Pp 2170-2179 (2022)
Abstract Background Hyperprogressive disease (HPD) is a novel pattern of the treatment course after immune checkpoint inhibitor (ICI) therapy in patients with non‐small cell lung cancer (NSCLC). This study aimed to investigate the clinical characte
Externí odkaz:
https://doaj.org/article/517e3bdb2df344c2b1eb5ef134c75b9a
Autor:
Su Yeon Lee, Young Chul Kim, Kye Young Lee, Sung Yong Lee, Shin Yup Lee, Min Ki Lee, Jeong Eun Lee, Seung Hun Jang, Tae‐Won Jang, Chang Min Choi
Publikováno v:
Thoracic Cancer, Vol 13, Iss 3, Pp 380-385 (2022)
Abstract Background Studies on the application of targeted therapies for patients with non‐small cell lung cancer (NSCLC) who harbor rare genetic mutations are ongoing. In the present study, we investigated the real‐world data of NSCLC patients w
Externí odkaz:
https://doaj.org/article/5731dffebc714c37be2e009cb1384db6
Autor:
Jang Hyuck Lee, Seung Soo Yoo, Mi Jeong Hong, Jin Eun Choi, Hyo‐Gyoung Kang, Sook Kyung Do, Won Kee Lee, Sun Ha Choi, Yong Hoon Lee, Hyewon Seo, Jaehee Lee, Shin Yup Lee, Seung Ick Cha, Chang Ho Kim, Eung Bae Lee, Sukki Cho, Sanghoon Jheon, Jae Yong Park
Publikováno v:
Molecular Oncology, Vol 16, Iss 3, Pp 750-763 (2022)
Bromodomain and extraterminal domain (BET) proteins are epigenetic readers that regulate gene expression. We investigated whether variants in BET genes are associated with survival outcomes for lung cancer. To do this, the associations between 77 var
Externí odkaz:
https://doaj.org/article/f5c68473d1074107a69f102376a022b6
Autor:
Jaehee Lee, Ji Eun Park, Sun Ha Choi, Hyewon Seo, Sang Yub Lee, Jae Kwang Lim, Seung Soo Yoo, Shin Yup Lee, Seung Ick Cha, Jae Yong Park, Chang Ho Kim
Publikováno v:
The Korean Journal of Internal Medicine, Vol 37, Iss 1, Pp 137-145 (2022)
Background/Aims Pleural fluid adenosine deaminase (ADA) levels are useful in discriminating tuberculous pleural effusions (TPEs) from malignant pleural effusions (MPEs). However, some patients with MPE exhibit high-ADA levels, which may mimic TPEs. T
Externí odkaz:
https://doaj.org/article/f0f85514077343ae9d87161023c150c7
Autor:
Hyo-Gyoung Kang, Yong Hoon Lee, Shin Yup Lee, Jin Eun Choi, Sook Kyung Do, Mi Jeong Hong, Jang Hyuck Lee, Ji Yun Jeong, Young Woo Do, Eung Bae Lee, Kyung Min Shin, Won Kee Lee, Sun Ha Choi, Hye won Seo, Seung Soo Yoo, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Sukki Cho, Sanghoon Jheon, Jae Yong Park
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract We investigated the association between genetic variants in the histone modification regions and the prognosis of lung adenocarcinoma after curative surgery. Potentially functional SNPs were selected using integrated analysis of ChIP-seq and
Externí odkaz:
https://doaj.org/article/ab77e259b9c54b8aab65c9c23d314e94
Autor:
Min Kyu Kang, Shin Yup Lee, Jin Eun Choi, Sook Kyung Do, Moon‐June Cho, Jun‐Sang Kim, Jae Yong Park
Publikováno v:
Cancer Medicine, Vol 10, Iss 22, Pp 8071-8078 (2021)
Abstract Background To investigate the impact of programmed death‐ligand 1 (PD‐L1) polymorphisms on the prognosis of non‐small cell lung cancer (NSCLC) patients treated with curative radiotherapy. Methods Four single nucleotide polymorphisms (S
Externí odkaz:
https://doaj.org/article/9fb4f3f87b164d22987a18702f7ec04d
Autor:
Taeyun Kim, Tae Won Jang, Chang Min Choi, Mi‐Hyun Kim, Sung Yong Lee, Cheol‐Kyu Park, Yoon Soo Chang, Kye Young Lee, Seung Joon Kim, Sei Hoon Yang, Jeong Seon Ryu, Jeong Eun Lee, Shin Yup Lee, Chan Kwon Park, Sang Hoon Lee, Seung Hun Jang, Seong Hoon Yoon
Publikováno v:
Cancer Medicine, Vol 10, Iss 17, Pp 5809-5822 (2021)
Abstract Objectives The optimal sequence for the administration of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) for treating non‐small cell lung cancer (NSCLC) is still unclear. This study aimed to evaluate the efficacy
Externí odkaz:
https://doaj.org/article/fbb820ad007b4aaaa5c7f065285aa49f
Autor:
Min Kyu Kang, Shin Yup Lee, Jin Eun Choi, Sun Ah Baek, Sook Kyung Do, Jeong Eun Lee, Jongmoo Park, Seung Soo Yoo, Sunha Choi, Kyung Min Shin, Ji Yun Jeong, Jae Yong Park
Publikováno v:
Thoracic Cancer, Vol 12, Iss 6, Pp 874-879 (2021)
Abstract Background To examine the impact of polymorphisms of glucose transporter 1 (GLUT1) gene on the prognosis of patients with stage III non‐small cell lung cancer (NSCLC) who received radiotherapy. Methods Five single nucleotide polymorphisms
Externí odkaz:
https://doaj.org/article/66a6410481ab408586f33f922e517f20