Zobrazeno 1 - 10
of 234
pro vyhledávání: '"Shin, Takasawa"'
Publikováno v:
Life, Vol 14, Iss 1, p 157 (2024)
Intermittent hypoxia (IH) is a central characteristic of sleep apnea syndrome (SAS), and it subjects cells in the body to repetitive apnea, chronic hypoxia, oxygen desaturation, and hypercapnia. Since SAS is linked to various serious cardiovascular c
Externí odkaz:
https://doaj.org/article/a41b80a768ca412aa4aea4166a3e9c11
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 12957 (2022)
Intermittent hypoxia (IH), one of the primary pathologies of sleep apnea syndrome (SAS), exposes cells throughout the body to repeated cycles of hypoxia/normoxia that result in oxidative stress and systemic inflammation. Since SAS is epidemiologicall
Externí odkaz:
https://doaj.org/article/cce909ecbeb74b0285ba7ba264fc305d
Autor:
Shin Takasawa, Asako Itaya-Hironaka, Mai Makino, Akiyo Yamauchi, Sumiyo Sakuramoto-Tsuchida, Tomoko Uchiyama, Ryogo Shobatake, Yoshinori Takeda, Hiroyo Ota
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12414 (2022)
Sleep apnea syndrome (SAS) is characterized by recurrent episodes of oxygen desaturation and reoxygenation (intermittent hypoxia [IH]), and is a risk factor for cardiovascular disease (CVD) and insulin resistance/Type 2 diabetes. However, the mechani
Externí odkaz:
https://doaj.org/article/02f9442ec6664bf383a05fb5f9a33338
Autor:
Shin Takasawa, Mai Makino, Tomoko Uchiyama, Akiyo Yamauchi, Sumiyo Sakuramoto-Tsuchida, Asako Itaya-Hironaka, Yoshinori Takeda, Keito Asai, Ryogo Shobatake, Hiroyo Ota
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8782 (2022)
Sleep apnea syndrome (SAS) is characterized by recurrent episodes of oxygen desaturation and reoxygenation (intermittent hypoxia, IH), and it is a risk factor for cardiovascular disease (CVD) and insulin resistance/type 2 diabetes. However, the mecha
Externí odkaz:
https://doaj.org/article/2cb9ff0be48d4736b7fac41033e3cd38
Autor:
Shin Takasawa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5299 (2022)
Sleep apnea syndrome (SAS) is the most common form of sleep-disordered breathing and is associated with many adverse health consequences, including increased overall mortality risk [...]
Externí odkaz:
https://doaj.org/article/015f85b1704449a0888637ce286dca8d
Autor:
Shin Takasawa, Ryogo Shobatake, Yoshinori Takeda, Tomoko Uchiyama, Akiyo Yamauchi, Mai Makino, Sumiyo Sakuramoto-Tsuchida, Keito Asai, Hiroyo Ota, Asako Itaya-Hironaka
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5868 (2022)
Sleep apnea syndrome (SAS), characterized by recurrent episodes of oxygen desaturation and reoxygenation (intermittent hypoxia (IH)), is a risk factor for hypertension and insulin resistance. We report a correlation between IH and insulin resistance/
Externí odkaz:
https://doaj.org/article/da3366e0d272470db10a95cef1318bf7
Autor:
Shin Takasawa
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4306 (2022)
Calcium (Ca2+) is a ubiquitous and fundamental signaling component that is utilized by cells to regulate a diverse range of cellular functions, such as insulin secretion from pancreatic β-cells of the islets of Langerhans. Cyclic ADP-ribose (cADPR),
Externí odkaz:
https://doaj.org/article/7abb92571a7a4ab5bb4aec489d523efc
Autor:
Shin Takasawa, Ryogo Shobatake, Asako Itaya‐Hironaka, Mai Makino, Tomoko Uchiyama, Sumiyo Sakuramoto‐Tsuchida, Yoshinori Takeda, Hiroyo Ota, Akiyo Yamauchi
Publikováno v:
Journal of Cellular and Molecular Medicine. 26:6019-6031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e529727f75de12ba888b47c5ffdeb0cd
https://doi.org/10.1111/jcmm.17618
https://doi.org/10.1111/jcmm.17618
Autor:
Yoji Kyotani, Asako Itaya‐Hironaka, Akiyo Yamauchi, Sumiyo Sakuramoto‐Tsuchida, Mai Makino, Shin Takasawa, Masanori Yoshizumi
Publikováno v:
FEBS Open Bio, Vol 8, Iss 5, Pp 868-876 (2018)
Patients with obstructive sleep apnea (OSA) experience repetitive episodes of desaturation and resaturation of blood oxygen (known as intermittent hypoxia or IH), during sleep. We showed previously that IH induced excessive proliferation of rat vascu
Externí odkaz:
https://doaj.org/article/6beaa8a64bf04daebb6eb0eaccca6605
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 364 (2021)
Sleep apnea syndrome (SAS) is a breathing disorder characterized by recurrent episodes of upper-airway collapse, resulting in intermittent hypoxia (IH) during sleep. Experimental studies with animals and cellular models have indicated that IH leads t
Externí odkaz:
https://doaj.org/article/127deff1ea9044cfb6d5de4a6fdfd64e