Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shimyn, Slomovic"'
Autor:
James J. Collins, James B. Niemi, Shimyn Slomovic, Tommaso Galbersanini, Hani M. Sallum, Nicolaas M. Angenent-Mari, Ally Huang, Rose A. Lee, Geoffrey Lansberry, Helena de Puig, Luis R. Soenksen, Peter Q. Nguyen, Nina M. Donghia, Evan M. Zhao
Publikováno v:
Nature Biotechnology. 39:1366-1374
Integrating synthetic biology into wearables could expand opportunities for noninvasive monitoring of physiological status, disease states and exposure to pathogens or toxins. However, the operation of synthetic circuits generally requires the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c947e1928fa2013740b293c6461ea61
https://doi.org/10.1038/s41587-021-00950-3
https://doi.org/10.1038/s41587-021-00950-3
Autor:
Peter Q, Nguyen, Luis R, Soenksen, Nina M, Donghia, Nicolaas M, Angenent-Mari, Helena, de Puig, Ally, Huang, Rose, Lee, Shimyn, Slomovic, Tommaso, Galbersanini, Geoffrey, Lansberry, Hani M, Sallum, Evan M, Zhao, James B, Niemi, James J, Collins
Publikováno v:
Nature biotechnology. 39(11)
Integrating synthetic biology into wearables could expand opportunities for noninvasive monitoring of physiological status, disease states and exposure to pathogens or toxins. However, the operation of synthetic circuits generally requires the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a89fab41b460fdfd92f74d50c7ef953
https://pubmed.ncbi.nlm.nih.gov/35314799
https://pubmed.ncbi.nlm.nih.gov/35314799
Autor:
Xiaoming Sun, Andyna Vernet, Ronglih Liao, Joseph V. Bonventre, George M. Church, Noah Davidsohn, Matthew J. Pezone, Daniel Oliver, Amanda R. Graveline, Shimyn Slomovic, Sukanya Punthambaker
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(47)
Comorbidity is common as age increases, and currently prescribed treatments often ignore the interconnectedness of the involved age-related diseases. The presence of any one such disease usually increases the risk of having others, and new approaches
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7752e4936a4b0882e8b8856478a310
https://pubmed.ncbi.nlm.nih.gov/31871168
https://pubmed.ncbi.nlm.nih.gov/31871168
Autor:
Shimyn Slomovic, James J. Collins
Publikováno v:
Nature Methods. 12:1085-1090
We generated synthetic protein components that can detect specific DNA sequences and subsequently trigger a desired intracellular response. These modular sensors exploit the programmability of zinc-finger DNA recognition to drive the intein-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8c9528e31a4725684669bc1b14bcede
https://doi.org/10.1038/nmeth.3585
https://doi.org/10.1038/nmeth.3585
Publikováno v:
Prof. Collins via Howard Silver
The increasing use of engineered organisms for industrial, clinical, and environmental applications poses a growing risk of spreading hazardous biological entities into the environment. To address this biosafety issue, significant effort has been inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68fc2de9c88a6e602bd8c176a05253c6
https://orcid.org/0000-0002-5560-8246
https://orcid.org/0000-0002-5560-8246
Autor:
Fern R. McSorley, Jeong Wook Lee, Yoshikazu Furuta, Christopher N. Boddy, Keith Pardee, Nina M. Donghia, Neel Joshi, Shimyn Slomovic, Peter Q. Nguyen, Andyna Vernet, Tom Ferrante, James J. Collins, Michael P. Lewandowski, Devin R. Burrill
Publikováno v:
Prof. Collins via Howard Silver
Synthetic biology uses living cells as molecular foundries for the biosynthesis of drugs, therapeutic proteins, and other commodities. However, the need for specialized equipment and refrigeration for production and distribution poses a challenge for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5b56fd1b43ac288a983aae822265d1
https://orcid.org/0000-0002-5560-8246
https://orcid.org/0000-0002-5560-8246
Autor:
Gadi Schuster, Shimyn Slomovic
Publikováno v:
Wiley Interdisciplinary Reviews: RNA. 2:106-123
RNA polyadenylation occurs in most forms of life, excluding a small number of biological systems. This posttranscriptional modification undertakes two roles, both of which influence the stability of the polyadenylated transcript. One is associated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bdee50576249de5ab9357ba1f80a0e5
https://doi.org/10.1002/wrna.45
https://doi.org/10.1002/wrna.45
Autor:
Shimyn Slomovic, Geurt Schilders, Reinout Raijmakers, Ger J.M. Pruijn, Alfred W. Bronkhorst, Gadi Schuster, Raymond H.J. Staals, Albert J. R. Heck
Publikováno v:
EMBO Journal, 29, 2358-2367
EMBO Journal, 29, 14, pp. 2358-2367
EMBO Journal, 29, 14, pp. 2358-2367
Item does not contain fulltext The exosome is an exoribonuclease complex involved in the degradation and maturation of a wide variety of RNAs. The nine-subunit core of the eukaryotic exosome is catalytically inactive and may have an architectural fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77158524799e29cd4824a99d456ed79
https://hdl.handle.net/2066/83868
https://hdl.handle.net/2066/83868
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1779:247-255
The addition of poly(A)-tails to RNA is a phenomenon common to almost all organisms. Not only homopolymeric poly(A)-tails, comprised exclusively of adenosines, but also heteropolymeric poly(A)-rich extensions, which include the other three nucleotide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2da019df45eaa39e0c0bfb2c13cf42
https://doi.org/10.1016/j.bbagrm.2007.12.004
https://doi.org/10.1016/j.bbagrm.2007.12.004
Publikováno v:
Nucleic Acids Research
The addition of poly(A)-tails to RNA is a process common to almost all organisms. In eukaryotes, stable poly(A)-tails, important for mRNA stability and translation initiation, are added to the 3' ends of most nuclear-encoded mRNAs, but not to rRNAs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657fe2784c2323e175ca86233c925d82
http://europepmc.org/articles/PMC1474067
http://europepmc.org/articles/PMC1474067