Synthesis and Structure-Activity Relationship of the Isoindolinyl Benzisoxazolpiperidines as Potent, Selective, and Orally Active Human Dopamine D4 Receptor Antagonists.

Autor: Hendrix, James A., Shimshock, Stephen J., Shutske, Gregory M., Tomer IV, John D., Kapples, Kevin J., Palermo, Mark G., Corbett, Thomas J. (Roy), Vargas, Hugo M., Kafka, Sharon, Brooks, Karen M., Laws-Ricker, Lynn, Lee, David K. H., de Lannoy, Inez, Bordeleau, Michel, Rizkalla, Geihan, Owolabi, Joshua, Kamboj, Rajender K.

Publikováno v: ChemBioChem; Oct2002, Vol. 3 Issue 10, p999-1009, 11p

Synthesis and structure-activity relationship of the isoindolinyl benzisoxazolpiperidines as potent, selective, and orally active human dopamine D4 receptor antagonists.

Autor: Hendrix JA; Aventis Pharmaceuticals Route, 202-206, PO Box 6800, Bridgewater, NJ 08807-0800, USA. james.hendrix@aventis.com, Shimshock SJ, Shutske GM, Tomer JD 4th, Kapples KJ, Palermo MG, Corbett TJ, Vargas HM, Kafka S, Brooks KM, Laws-Ricker L, Lee DK, de Lannoy I, Bordeleau M, Rizkalla G, Owolabi J, Kamboj RK

Publikováno v: Chembiochem : a European journal of chemical biology [Chembiochem] 2002 Oct 04; Vol. 3 (10), pp. 999-1009.