Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aβ/amyloid burden in a transgenic mouse model of Alzheimer's disease

Autor: Bosetti Francesca, Wetzel Ronald, Dealwis Chris, Prendergast Jay S, Rebeck G William, Mocchetti Italo, Niikura Takako, Aid Saba, Shimoji Mika, Sidahmed Elkhansa, Minami S Sakura, Matsuoka Yasuji, Hoe Hyang-Sook, Turner R Scott

Publikováno v: Journal of Neuroinflammation, Vol 7, Iss 1, p 57 (2010)

Abstract Background Passive immunization with antibodies directed to Aβ decreases brain Aβ/amyloid burden and preserves memory in transgenic mouse models of Alzheimer's disease (AD). This therapeutic strategy is under intense scrutiny in clinical s

Externí odkaz: https://doaj.org/article/acb5dad78df74d0e9a48d02634907856

CXCR4 and CXCL12 Expression is Increased in the Nigro-Striatal System of Parkinson’s Disease.

Autor: Shimoji, Mika¹, Pagan, Fernando², Healton, Edward B.², Mocchetti, Italo¹ moccheti@georgetown.edu

Publikováno v: Neurotoxicity Research. 2009, Vol. 16 Issue 3, p318-328. 11p. 4 Diagrams, 3 Charts, 2 Graphs.

Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Abeta/amyloid burden in a transgenic mouse model of Alzheimer's disease

Autor: Minami, S Sakura, Sidahmed, Elkhansa, Aid, Saba, Shimoji, Mika, Niikura, Takako, Mocchetti, Italo, Rebeck, G William, Prendergast, Jay S, Dealwis, Chris, Wetzel, Ronald, Bosetti, Francesca, Matsuoka, Yasuji, Hoe, Hyang-Sook, Turner, R Scott

Publikováno v: Minami, S Sakura; Sidahmed, Elkhansa; Aid, Saba; Shimoji, Mika; Niikura, Takako; Mocchetti, Italo; et al.(2010). Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Abeta/amyloid burden in a transgenic mouse model of Alzheimer's disease. Journal of Neuroinflammation, 7(1), 57. doi: http://dx.doi.org/10.1186/1742-2094-7-57. Retrieved from: http://www.escholarship.org/uc/item/9k25h5kv

Background Passive immunization with antibodies directed to Aβ decreases brain Aβ/amyloid burden and preserves memory in transgenic mouse models of Alzheimer's disease (AD). This therapeutic strategy is under intense scrutiny in clinical studies, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::7805a0b53a743b548aa4569c8157aa5a
http://www.escholarship.org/uc/item/9k25h5kv

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