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Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Autor: Amare, Azmeraw T., Schubert, Klaus Oliver, Hou, Liping, Clark, Scott R., Papiol, Sergi, Cearns, Micah, Heilbronner, Urs, Degenhardt, Franziska, Tekola-Ayele, Fasil, Hsu, Yi Hsiang, Shekhtman, Tatyana, Adli, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Biernacka, Joanna M., Birner, Armin, Brichant-Petitjean, Clara, Cervantes, Pablo, Chen, Hsi Chung, Chillotti, Caterina, Cichon, Sven, Cruceanu, Cristiana, Czerski, Piotr M., Dalkner, Nina, Dayer, Alexandre, Del Zompo, Maria, DePaulo, J. Raymond, Étain, Bruno, Jamain, Stephane, Falkai, Peter, Forstner, Andreas J., Frisen, Louise, Frye, Mark A., Fullerton, Janice M., Gard, Sébastien, Garnham, Julie S., Goes, Fernando S., Grigoroiu-Serbanescu, Maria, Grof, Paul, Hashimoto, Ryota, Hauser, Joanna, Herms, Stefan, Hoffmann, Per, Hofmann, Andrea, Jiménez, Esther, Kahn, Jean Pierre, Kassem, Layla, Kuo, Po Hsiu, Kato, Tadafumi, Kelsoe, John R., Kittel-Schneider, Sarah, Kliwicki, Sebastian, König, Barbara, Kusumi, Ichiro, Laje, Gonzalo, Landén, Mikael, Lavebratt, Catharina, Leboyer, Marion, Leckband, Susan G., Tortorella, Alfonso, Manchia, Mirko, Martinsson, Lina, McCarthy, Michael J., McElroy, Susan L., Colom, Francesc, Mitjans, Marina, Mondimore, Francis M., Monteleone, Palmiero, Nievergelt, Caroline M., Nöthen, Markus M., Novák, Tomas, O’Donovan, Claire, Ozaki, Norio, Ösby, Urban, Pfennig, Andrea, Potash, James B., Reif, Andreas, Wray, Naomi R., Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Adams, Mark J., Agerbo, Esben, Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas H.R., Bryois, Julien, Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane varregaard, Clarke, Toni Kim, Coleman, Jonathan R.I., Colodro-Conde, Lucía, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E., Davies, Gail, Deary, Ian J., Derks, Eske M., Direk, Nese, Dolan, Conor V., Dunn, Erin C., Eley, Thalia C., Escott-Price, Valentina, Kiadeh, Farnush Farhadi Hassan, Finucane, Hilary K., Frank, Josef, Gaspar, Héléna A., Gill, Michael, Gordon, Scott D., Grove, Jakob, Hall, Lynsey S., Hansen, Christine Søholm, Hansen, Thomas F., Hickie, Ian B., Homuth, Georg, Horn, Carsten, Hottenga, Jouke Jan, Hougaard, David M., Ising, Marcus, Jansen, Rick, Jorgenson, Eric, Knowles, James A., Kohane, Isaac S., Kraft, Julia, Kretzschmar, Warren W., Krogh, Jesper, Kutalik, Zoltán, Li, Yihan, Lind, Penelope A., MacIntyre, Donald J., MacKinnon, Dean F., Maier, Robert M., Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, McGuffin, Peter, Medland, Sarah E., Mehta, Divya, Middeldorp, Christel M., Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Montgomery, Grant W., Mostafavi, Sara, Mullins, Niamh, Nauck, Matthias, Ng, Bernard, Nivard, Michel G., Nyholt, Dale R., O’Reilly, Paul F., Oskarsson, Hogni, Owen, Michael J., Painter, Jodie N., Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Peterson, Roseann E., Pettersson, Erik, Peyrot, Wouter J., Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A., Qvist, Per, Rice, John P., Riley, Brien P., Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C., Shen, Ling, Shi, Jianxin, Shyn, Stanley I., Sigurdsson, Engilbert, Sinnamon, Grant C.B., Smit, Johannes H., Smith, Daniel J., Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E., Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A., Thorgeirsson, Thorgeir E., Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, André G., Umbricht, Daniel, Van der Auwera, Sandra, van Hemert, Albert M., Viktorin, Alexander, Visscher, Peter M., Wang, Yunpeng, Webb, Bradley T., Weinsheimer, Shantel Marie, Wellmann, Jürgen, Willemsen, Gonneke, Witt, Stephanie H., Wu, Yang, Xi, Hualin S., Yang, Jian, Zhang, Futao, Arolt, Volker, Baune, Bernhard T., Berger, Klaus, Boomsma, Dorret I., Dannlowski, Udo, de Geus, E. J.C., Domenici, Enrico, Domschke, Katharina, Esko, Tõnu, Grabe, Hans J., Hamilton, Steven P., Hayward, Caroline, Heath, Andrew C., Kendler, Kenneth S., Kloiber, Stefan, Lewis, Glyn, Li, Qingqin S., Lucae, Susanne, Madden, Pamela A.F., Magnusson, Patrik K., Martin, Nicholas G., McIntosh, Andrew M., Metspalu, Andres, Mors, Ole, Mortensen, Preben Bo, Müller-Myhsok, Bertram, Nordentoft, Merete, O’Donovan, Michael C., Paciga, Sara A., Pedersen, Nancy L., Penninx, Brenda W.J.H., Perlis, Roy H., Porteous, David J., Preisig, Martin, Rietschel, Marcella, Schaefer, Catherine, Schulze, Thomas G., Smoller, Jordan W., Stefansson, Kari, Tiemeier, Henning, Uher, Rudolf, Völzke, Henry, Weissman, Myrna M., Werge, Thomas, Lewis, Cathryn M., Levinson, Douglas F., Breen, Gerome, Børglum, Anders D., Sullivan, Patrick F., Reininghaus, Eva, Rouleau, Guy A., Rybakowski, Janusz K., Schalling, Martin, Schofield, Peter R., Schweizer, Barbara W., Severino, Giovanni, Shilling, Paul D., Shimoda, Katzutaka, Simhandl, Christian, Slaney, Claire M., Squassina, Alessio, Stamm, Thomas, Stopkova, Pavla, Maj, Mario, Turecki, Gustavo, Vieta, Eduard, Veeh, Julia, Wright, Adam, Zandi, Peter P., Mitchell, Philip B., Bauer, Michael, Alda, Martin, McMahon, Francis J.

Publikováno v: Molecular Psychiatry, 26(6), 2457-2470. Nature Publishing Group
Amare, A T, Baune, B T, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Mbarek, H, Middeldorp, C M, Nivard, M G, Willemsen, G, Boomsma, D I, de Geus, E J C, Beekman, A F T, Jansen, R, Milaneschi, Y, Peyrot, W J, Smit, J H, W J H Penninx, B & Posthuma, D 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, no. 6, pp. 2457-2470 . https://doi.org/10.1038/s41380-020-0689-5
Amare, A T, Schubert, K O, Hou, L, Clark, S R, Papiol, S, Cearns, M, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hsu, Y H, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, J M, Backlund, L, Bhattacharjee, A K, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Cervantes, P, Chen, H C, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, P M, Dalkner, N, Dayer, A, Del Zompo, M, DePaulo, J R, Étain, B, Jamain, S, Falkai, P, Forstner, A J, Frisen, L, Frye, M A, Fullerton, J M, Nordentoft, M, Werge, T, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N R, Ripke, S, Matthiesen, M, Agerbo, E, Bækvad-Hansen, M, Buttenschøn, H N, Bybjerg-Grauholm, J, Grove, J, Hansen, C S, Hansen, T F, Hougaard, D M, Krogh, J, Pedersen, C B, Pedersen, M G, Qvist, P, Thompson, W K, Wang, Y, Weinsheimer, S M, Mortensen, P B, Christensen, J V & Børglum, A D 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, pp. 2457–2470 . https://doi.org/10.1038/s41380-020-0689-5
Molecular psychiatry 26(6), 2457-2470 (2021). doi:10.1038/s41380-020-0689-5
Molecular Psychiatry
Molecular Psychiatry, 2021, Online ahead of print. ⟨10.1038/s41380-020-0689-5⟩
Amare, A T, Schubert, K O, Hou, L, Clark, S R, Papiol, S, Cearns, M, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hsu, Y H, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, J M, Backlund, L, Bhattacharjee, A K, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Cervantes, P, Chen, H C, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, P M, Dalkner, N, Dayer, A, Del Zompo, M, DePaulo, J R, Étain, B, Jamain, S, Falkai, P, Forstner, A J, Frisen, L, Frye, M A, Fullerton, J M, Gard, S, Garnham, J S, Goes, F S, Grigoroiu-Serbanescu, M, Grof, P, Hashimoto, R, Hauser, J, Herms, S, Hoffmann, P, Hofmann, A, Jiménez, E, Kahn, J P, Kassem, L, Kuo, P H, Kato, T, Kelsoe, J R, Kittel-Schneider, S, Kliwicki, S, König, B, Kusumi, I, Laje, G, Landén, M, Lavebratt, C, Leboyer, M, Leckband, S G, Tortorella, A, Manchia, M, Martinsson, L, McCarthy, M J, McElroy, S L, Colom, F, Mitjans, M, Mondimore, F M, Monteleone, P, Nievergelt, C M, Nöthen, M M, Novák, T, O’Donovan, C, Ozaki, N, Ösby, U, Pfennig, A, Potash, J B, Reif, A, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Blackwood, D H R, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J V, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J J, Hougaard, D M, Ising, M, Jansen, R, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Krogh, J, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Reininghaus, E, Rouleau, G A, Rybakowski, J K, Schalling, M, Schofield, P R, Schweizer, B W, Severino, G, Shilling, P D, Shimoda, K, Simhandl, C, Slaney, C M, Squassina, A, Stamm, T, Stopkova, P, Maj, M, Turecki, G, Vieta, E, Veeh, J, Witt, S H, Wright, A, Zandi, P P, Mitchell, P B, Bauer, M, Alda, M, Rietschel, M, McMahon, F J, Schulze, T G, Baune, B T & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, no. 6, pp. 2457-2470 . https://doi.org/10.1038/s41380-020-0689-5
Amare, A T, Schubert, K O, Hou, L, Clark, S R, Papiol, S, Cearns, M, Heilbronner, U, Degenhardt, F, Tekola-Ayele, F, Hsu, Y-H, Shekhtman, T, Adli, M, Akula, N, Akiyama, K, Ardau, R, Arias, B, Aubry, J-M, Backlund, L, Bhattacharjee, A K, Bellivier, F, Benabarre, A, Bengesser, S, Biernacka, J M, Birner, A, Brichant-Petitjean, C, Cervantes, P, Chen, H-C, Chillotti, C, Cichon, S, Cruceanu, C, Czerski, P M, Dalkner, N, Dayer, A, Del Zompo, M, DePaulo, J R, Étain, B, Jamain, S, Falkai, P, Forstner, A J, Frisen, L, Frye, M A, Fullerton, J M, Gard, S, Garnham, J S, Goes, F S, Grigoroiu-Serbanescu, M, Grof, P, Hashimoto, R, Hauser, J, Herms, S & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2021, ' Association of polygenic score for major depression with response to lithium in patients with bipolar disorder ', Molecular Psychiatry, vol. 26, no. 6, pp. 2457-2470 . https://doi.org/10.1038/s41380-020-0689-5
Molecular Psychiatry, Nature Publishing Group, 2021, Online ahead of print. ⟨10.1038/s41380-020-0689-5⟩
Molecular Psychiatry (2020)
Molecular psychiatry, 26(6), 2457-2470. Nature Publishing Group

© 2020, The Author(s), under exclusive licence to Springer Nature Limited.Lithium is a first-line medication for bipolar disorder (BD), but only one in three patients respond optimally to the drug. Since evidence shows a strong clinical and genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edcaa7338db07c72a64e32d0cc9bef51
http://www.scopus.com/inward/record.url?scp=85081737215&partnerID=8YFLogxK

Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients

Autor: Schubert, Klaus Oliver, Thalamuthu, Anbupalam, Amare, Azmeraw T, Frank, Joseph, Streit, Fabian, Adl, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Biernacka, Joanna M, Birner, Armin, Marie-Claire, Cynthia, Cearns, Micah, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven, Clark, Scott R, Cruceanu, Cristiana, Czerski, Piotr M, Dalkner, Nina, Dayer, Alexandre, Degenhardt, Franziska, Del Zompo, Maria, DePaulo, J Raymond, Étain, Bruno, Falkai, Peter, Forstner, Andreas J, Frisen, Louise, Frye, Mark A, Fullerton, Janice M, Gard, Sébastien, Garnham, Julie S, Goes, Fernando S, Grigoroiu-Serbanescu, Maria, Grof, Paul, Hashimoto, Ryota, Hauser, Joanna, Heilbronner, Urs, Herms, Stefan, Hoffmann, Per, Hou, Liping, Hsu, Yi-Hsiang, Jamain, Stephane, Jiménez, Esther, Kahn, Jean-Pierre, Kassem, Layla, Kuo, Po-Hsiu, Kato, Tadafumi, Kelsoe, John, Kittel-Schneider, Sarah, Ferensztajn-Rochowiak, Ewa, König, Barbara, Kusumi, Ichiro, Laje, Gonzalo, Landén, Mikael, Lavebratt, Catharina, Leboyer, Marion, Leckband, Susan G, Maj, Mario, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Manchia, Mirko, Martinsson, Lina, McCarthy, Michael J, McElroy, Susan, Colom, Francesc, Mitjans, Marina, Mondimore, Francis M, Monteleone, Palmiero, Nievergelt, Caroline M, Nöthen, Markus M, Novák, Tomas, O'Donovan, Claire, Ozaki, Norio, Ösby, Urban, Papiol, Sergi, Pfennig, Andrea, Pisanu, Claudia, Potash, James B, Reif, Andreas, Reininghaus, Eva, Rouleau, Guy A, Rybakowski, Janusz K, Schalling, Martin, Schofield, Peter R, Schweizer, Barbara W, Severino, Giovanni, Shekhtman, Tatyana, Shilling, Paul D, Shimoda, Katzutaka, Simhandl, Christian, Slaney, Claire M, Squassina, Alessio

Publikováno v: Translational psychiatry, vol 11, iss 1

Lithium is the gold standard therapy for Bipolar Disorder (BD) but its effectiveness differs widely between individuals. The molecular mechanisms underlying treatment response heterogeneity are not well understood, and personalized treatment in BD re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::5f9a25cbb78bd7c7317979560298e889
https://escholarship.org/uc/item/5wj6h885

Association of ADHD and depression polygenic scores with lithium response: A Consortium for Lithium Genetics study

Autor: Coombes, Brandon J, Millischer, Vincent, Amare, Azmeraw T, Vieta, Eduard, Witt, Stephanie H, Zandi, Peter P, Fullerton, Janice M, Alda, Martin, Frye, Mark A, Schulze, Thomas G, McMahon, Francis J, Biernacka, Joanna M, Ardau, Raffaella, Arias, Barbara, Aubry, Jean-Michel, Backlund, Lena, Bauer, Michael, Baune, Bernhard T, Bellivier, Frank, Benabarre, Antoni, Bengesser, Susanne, Batzler, Anthony, Bhattacharjee, Abesh Kumar, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven, Clark, Scott R, Colom, Francesc, Cruceanu, Cristiana, Czerski, Piotr M, Dalkner, Nina, Larrabee, Beth, Degenhardt, Franziska, Zompo, Maria Del, DePaulo, J Raymond, Étain, Bruno, Falkai, Peter, Ferensztajn-Rochowiak, Ewa, Forstner, Andreas J, Frisen, Louise, Gard, Sébastien, Garnham, Julie S, Hou, Liping, Goes, Fernando S, Grigoroiu-Serbanescu, Maria, Grof, Paul, Hashimoto, Ryota, Hauser, Joanna, Herms, Stefan, Hoffmann, Per, Jamain, Stephane, Jiménez, Esther, Kahn, Jean-Pierre, Papiol, Sergi, Kassem, Layla, Kato, Tadafumi, Kelsoe, John R, Kittel-Schneider, Sarah, König, Barbara, Kuo, Po-Hsiu, Kusumi, Ichiro, Laje, Gonzalo, Landén, Mikael, Lavebratt, Catharina, Heilbronner, Urs, Leboyer, Marion, Leckband, Susan G, Maj, Mario, Manchia, Mirko, Martinsson, Lina, McCarthy, Michael J, McElroy, Susan L, Mitchell, Philip B, Mitjans, Marina, Mondimore, Francis M, Adli, Mazda, Monteleone, Palmiero, Nievergelt, Caroline M, Nöthen, Markus M, Novák, Tomas, O'Donovan, Claire, Osby, Urban, Ozaki, Norio, Pfennig, Andrea, Pisanu, Claudia, Potash, James B, Akiyama, Kazufumi, Reif, Andreas, Reininghaus, Eva, Rietschel, Marcella, Rouleau, Guy A, Rybakowski, Janusz K, Schalling, Martin, Schofield, Peter R, Schubert, Klaus Oliver, Schweizer, Barbara W, Severino, Giovanni, Akula, Nirmala, Shekhtman, Tatyana, Shilling, Paul D, Shimoda, Katzutaka, Simhandl, Christian, Slaney, Claire M, Squassina, Alessio, Stamm, Thomas, Stopkova, Pavla, Tortorella, Alfonso, Turecki, Gustavo

Publikováno v: Complex psychiatry (2021).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3364::3189c51e067476f1b6d5bdf1ef75294e
https://hdl.handle.net/2128/28692

Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder

Autor: Amare, Azmeraw, Schubert, Klaus Oliver, Hou, Liping, Clark, Scott, Papiol, Sergi, Heilbronner, Urs, Degenhardt, Franziska, Tekola-Ayele, Fasil, Hsu, Yi-Hsiang, Shekhtman, Tatyana, Adli, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Biernacka, Joanna, Birner, Armin, Brichant-Petitjean, Clara, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven, Cruceanu, Cristiana, Czerski, Piotr, Dalkner, Nina, Dayer, Alexandre, del Zompo, Maria, Depaulo, J Raymond, Étain, Bruno, Falkai, Peter, Forstner, Andreas, Frisen, Louise, Frye, Mark, Fullerton, Janice, Gard, Sébastien, Garnham, Julie, Goes, Fernando, Grigoroiu-Serbanescu, Maria, Grof, Paul, Hashimoto, Ryota, Hauser, Joanna, Herms, Stefan, Hoffmann, Per, Hofmann, Andrea, Jamain, Stephane, Jiménez, Esther, Kahn, Jean-Pierre, Kassem, Layla, Kuo, Po-Hsiu, Kato, Tadafumi, Kelsoe, John, Kittel-Schneider, Sarah, Kliwicki, Sebastian, König, Barbara, Kusumi, Ichiro, Laje, Gonzalo, Landén, Mikael, Lavebratt, Catharina, Leboyer, Marion, Leckband, Susan, Tortorella, Alfonso, Manchia, Mirko, Martinsson, Lina, Mccarthy, Michael, Mcelroy, Susan, Colom, Francesc, Mitjans, Marina, Mondimore, Francis, Monteleone, Palmiero, Nievergelt, Caroline, Nöthen, Markus, Novák, Tomas, O'Donovan, Claire, Ozaki, Norio, Ösby, Urban, Pfennig, Andrea, Potash, James, Reif, Andreas, Reininghaus, Eva, Rouleau, Guy, Rybakowski, Janusz, Schalling, Martin, Schofield, Peter, Schweizer, Barbara, Severino, Giovanni, Shilling, Paul, Shimoda, Katzutaka, Simhandl, Christian, Slaney, Claire, Squassina, Alessio, Stamm, Thomas, Stopkova, Pavla, Maj, Mario, Turecki, Gustavo, Vieta, Eduard, Volkert, Julia, Witt, Stephanie, Wright, Adam, Zandi, Peter, Mitchell, Philip, Bauer, Michael, Alda, Martin, Rietschel, Marcella, Mcmahon, Francis, Schulze, Thomas, Baune, Bernhard, Depaulo, J. Raymond, O’donovan, Claire

Publikováno v: JAMA Psychiatry
JAMA Psychiatry, Chicago, IL : American Medical Association, [2013]-, 2018, 75 (1), pp.65-74. ⟨10.1001/jamapsychiatry.2017.3433⟩

International audience; Importance: Lithium is a first-line mood stabilizer for the treatment of bipolar affective disorder (BPAD). However, the efficacy of lithium varies widely, with a nonresponse rate of up to 30%. Biological response markers are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::92d585e3b50a7afed013b2c7c934e770
https://www.hal.inserm.fr/inserm-03854545