Integrated analysis of effect of daisaikoto, a traditional Japanese medicine, on the metabolome and gut microbiome in a mouse model of nonalcoholic fatty liver disease.

Autor: Ishizawa S; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan., Nishi A; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan. Electronic address: nishi_akinori@mail.tsumura.co.jp., Kaifuchi N; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan., Shimobori C; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan., Nahata M; Tsumura Kampo Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan., Yamada C; Tsumura Kampo Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan., Iizuka S; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan., Ohbuchi K; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan., Nishiyama M; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan., Fujitsuka N; Tsumura Kampo Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan., Kono T; Department of Gastroenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Hokkaido 060-8638, Japan; Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital, Sapporo, Hokkaido 065-0033, Japan., Yamamoto M; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ami, Ibaraki 300-1192, Japan.

Publikováno v: Gene [Gene] 2022 Dec 20; Vol. 846, pp. 146856. Date of Electronic Publication: 2022 Sep 05.

Decline in Liver Mitochondria Metabolic Function Is Restored by Hochuekkito Through Sirtuin 1 in Aged Mice With Malnutrition.

Autor: Nahata M; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Fujitsuka N; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Sekine H; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Shimobori C; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ibaraki, Japan., Ohbuchi K; Tsumura Advanced Technology Research Laboratories, Tsumura & Co., Ibaraki, Japan., Iizuka S; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Mogami S; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Ohnishi S; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan., Takeda H; Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.; Gastroenterology, Tokeidai Memorial Hospital, Sapporo, Japan.

Publikováno v: Frontiers in physiology [Front Physiol] 2022 Mar 01; Vol. 13, pp. 848960. Date of Electronic Publication: 2022 Mar 01 (Print Publication: 2022).

Effects of maoto (ma-huang-tang) on host lipid mediator and transcriptome signature in influenza virus infection.

Autor: Nishi A; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan. nishi_akinori@mail.tsumura.co.jp., Kaifuchi N; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Shimobori C; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Ohbuchi K; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Iizuka S; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Sugiyama A; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Ogura K; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Yamamoto M; Tsumura Kampo Research Laboratories, Tsumura & Co., Ibaraki, Japan., Kuroki H; Sotobo Children's Clinic, Medical Corporation Shigyo-No-Kai, Isumi, Chiba, Japan., Nabeshima S; General Medicine, Fukuoka University Hospital, Fukuoka, Japan., Yachie A; The Systems Biology Institute, Shinagawa, Tokyo, Japan., Matsuoka Y; The Systems Biology Institute, Shinagawa, Tokyo, Japan., Kitano H; The Systems Biology Institute, Shinagawa, Tokyo, Japan.

Publikováno v: Scientific reports [Sci Rep] 2021 Feb 19; Vol. 11 (1), pp. 4232. Date of Electronic Publication: 2021 Feb 19.

Phenotyping analysis of the Japanese Kampo medicine maoto in healthy human subjects using wide-targeted plasma metabolomics.

Autor: Kitagawa H; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Ohbuchi K; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan. Electronic address: oobuchi_katsuya@mail.tsumura.co.jp., Munekage M; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Fujisawa K; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Kawanishi Y; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Namikawa T; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Kushida H; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Matsumoto T; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Shimobori C; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Nishi A; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Sadakane C; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Watanabe J; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Yamamoto M; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Hanazaki K; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan.

Publikováno v: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2019 Feb 05; Vol. 164, pp. 119-127. Date of Electronic Publication: 2018 Oct 22.

Data on metabolic profiling of healthy human subjects' plasma before and after administration of the Japanese Kampo medicine maoto.

Autor: Kitagawa H; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Ohbuchi K; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Munekage M; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Fujisawa K; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Kawanishi Y; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Namikawa T; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan., Kushida H; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Matsumoto T; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Shimobori C; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Nishi A; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Sadakane C; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Watanabe J; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Yamamoto M; Tsumura Kampo Research Laboratories, Tsumura & CO., Ibaraki, Japan., Hanazaki K; Department of Surgery, Kochi Medical School, Kochi University, Kochi, Japan.

Publikováno v: Data in brief [Data Brief] 2018 Dec 03; Vol. 22, pp. 359-364. Date of Electronic Publication: 2018 Dec 03 (Print Publication: 2019).