Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Shimaa M Elshazly"'
Autor:
Nevertyty Mohamed Mahmoud, Shimaa M. Elshazly, Fatma El-shaarawy, Sawsan A. Zaitone, Afaf A. Aldahish, Gehan A. Ahmed, Manal S. Fawzy, Sheka Yagub Aloyouni, Sally Y. Abed, Tahani Saeedi, Shaimaa S. El-Sayed
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectivesHepatotoxicity is a severe outcome of methotrexate (MTX) therapy, limiting its clinical use and contributing to its related morbidity and mortality. This study investigated the hepatoprotective effects of nitazoxanide (NTZ), an antiprotozoa
Externí odkaz:
https://doaj.org/article/b38c16f06da1443e937e9ad8a0f27d30
Publikováno v:
The Saudi Journal of Gastroenterology, Vol 18, Iss 3, Pp 182-187 (2012)
Background/Aim: Portal hypertension is an important and potentially fatal complication of liver disease whereby cellular and fibrotic alterations manifest to increase portal venous pressure. The aim of this study is to investigate the effect of capto
Externí odkaz:
https://doaj.org/article/7d402d6dedd342c8a94b1cf6e8f1c2d6
Autor:
Amr A A Mahmoud, Shimaa M Elshazly
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106993 (2014)
The metabolic syndrome (MS) is characterized by insulin resistance, dyslipidemia and hypertension. It is associated with increased risk of cardiovascular diseases and type-2 diabetes. Consumption of fructose is linked to increased prevalence of MS. U
Externí odkaz:
https://doaj.org/article/a6ff2ecd574e4dd19f96e3ff4969eccf
Autor:
Nancy M. Abdel-Kareem, Shimaa M. Elshazly, May A. Abd El Fattah, Afaf A. Aldahish, Sawsan A. Zaitone, Sahar K. Ali, Enas A. Abd El-Haleim
Publikováno v:
Pharmaceuticals, Vol 17, Iss 8, p 1054 (2024)
Insulin resistance, induced by high fructose consumption, affects cognitive function negatively. Nifedipine may be suggested for neurological disorders. This study aimed to assess the effect of nifedipine with either a normal diet (ND) or a ketogenic
Externí odkaz:
https://doaj.org/article/44691b0bddc74167a39f5f46ec1e0551
Publikováno v:
International immunopharmacology. 115
Diabetic nephropathy (DN) is a major cause of end-stage renal disease (ESRD). Agomelatine, a melatonin receptor agonist, has a potent anti-inflammatory activity. The current study aimed to determine the ameliorative anti-inflammatory effect of agomel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e38cb56a7b21f232226e45d9d3c3de9
https://pubmed.ncbi.nlm.nih.gov/36587501
https://pubmed.ncbi.nlm.nih.gov/36587501
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 394:2117-2128
The incidence of chronic kidney disease is escalating; cardiorenal syndrome (CRS) type 4 is gaining a major health concern causing significant morbidity and mortality, putting major burdens on the healthcare system. This study was designed to compare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a37e68c260684836cf9513ecd6b5e2d3
https://doi.org/10.1007/s00210-021-02130-1
https://doi.org/10.1007/s00210-021-02130-1
Publikováno v:
International Urology and Nephrology. 53:1713-1721
Acute kidney injury (AKI), secondary to renal ischemia/reperfusion (I/R), is a serious problem associated with high mortality. The pathophysiology of AKI after renal I/R involves peroxynitrite production; hence, scavenging this metabolite may rescue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5b6081518358dbe2e50b6ca446470183
https://doi.org/10.1007/s11255-021-02827-5
https://doi.org/10.1007/s11255-021-02827-5
Publikováno v:
Pharmacological Reports. 72:956-968
Upregulation of the sodium glucose co-transporter (SGLT2) is implicated in acute renal injury (ARI) progression and is regulated by extracellular signal-regulated kinase (ERK), hypoxia-inducible factor 1 alpha (HIF1α) or prostaglandin E2 (PGE2). Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cac5f444e01f669a2a213dda5ede41e
https://doi.org/10.1007/s43440-020-00059-5
https://doi.org/10.1007/s43440-020-00059-5
Publikováno v:
Life sciences. 291
The nephrotoxicity of cyclosporine A (CsA) limits its use as an immunosuppressant. Wnt/β-catenin signaling is involved in the pathogenesis of both acute and chronic kidney disease, and it is inhibited by peroxisome proliferator-activated receptor ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b231dc7d6bfc3eb010cb921d799a615
https://pubmed.ncbi.nlm.nih.gov/34968469
https://pubmed.ncbi.nlm.nih.gov/34968469
Publikováno v:
Advances in Pharmacological Sciences, Vol 2015 (2015)
Spirulina is a blue-green alga used as a dietary supplement. It has been shown to possess anti-inflammatory, antioxidant, and hepatoprotective properties. This study was designed to evaluate the antitumor effect of spirulina (200 and 800 mg/kg) again
Externí odkaz:
https://doaj.org/article/cad16b0b4ec54086a37aca5b74681620