Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Shilpa S Iyer"'
Autor:
Lorenzo Subissi, Anne von Gottberg, Lipi Thukral, Nathalie Worp, Bas B. Oude Munnink, Surabhi Rathore, Laith J. Abu-Raddad, Ximena Aguilera, Erik Alm, Brett N. Archer, Homa Attar Cohen, Amal Barakat, Wendy S. Barclay, Jinal N. Bhiman, Leon Caly, Meera Chand, Mark Chen, Ann Cullinane, Tulio de Oliveira, Christian Drosten, Julian Druce, Paul Effler, Ihab El Masry, Adama Faye, Simani Gaseitsiwe, Elodie Ghedin, Rebecca Grant, Bart L. Haagmans, Belinda L. Herring, Shilpa S. Iyer, Zyleen Kassamali, Manish Kakkar, Rebecca J. Kondor, Juliana A. Leite, Yee-Sin Leo, Gabriel M. Leung, Marco Marklewitz, Sikhulile Moyo, Jairo Mendez-Rico, Nada M. Melhem, Vincent Munster, Karen Nahapetyan, Djin-Ye Oh, Boris I. Pavlin, Thomas P. Peacock, Malik Peiris, Zhibin Peng, Leo L. M. Poon, Andrew Rambaut, Jilian Sacks, Yinzhong Shen, Marilda M. Siqueira, Sofonias K. Tessema, Erik M. Volz, Volker Thiel, Sylvie van der Werf, Sylvie Briand, Mark D. Perkins, Maria D. Van Kerkhove, Marion P. G. Koopmans, Anurag Agrawal
Publikováno v:
Nature Medicine
Nature Medicine, 2022, 28 (6), pp.1110-1115. ⟨10.1038/s41591-022-01836-w⟩
Nature Medicine, 28(6), 1110-1115. Nature Publishing Group
Nature Medicine, 2022, 28 (6), pp.1110-1115. ⟨10.1038/s41591-022-01836-w⟩
Nature Medicine, 28(6), 1110-1115. Nature Publishing Group
International audience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301b16846e7ffa38ab66d475410b1270
https://hal-pasteur.archives-ouvertes.fr/pasteur-04098063
https://hal-pasteur.archives-ouvertes.fr/pasteur-04098063
Autor:
Dorota Kmiec, Shilpa S. Iyer, Christina M. Stürzel, Daniel Sauter, Beatrice H. Hahn, Frank Kirchhoff
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) groups M, N, O, and P are the result of independent zoonotic transmissions of simian immunodeficiency viruses (SIVs) infecting great apes in Africa. Among these, only Vpu proteins of pandemic HIV-1
Externí odkaz:
https://doaj.org/article/6dae67beccce4aa2b37a5b00912b36fb
Autor:
Hannah J. Barbian, Julie M. Decker, Frederic Bibollet-Ruche, Rachel P. Galimidi, Anthony P. West, Gerald H. Learn, Nicholas F. Parrish, Shilpa S. Iyer, Yingying Li, Craig S. Pace, Ruijiang Song, Yaoxing Huang, Thomas N. Denny, Hugo Mouquet, Loic Martin, Priyamvada Acharya, Baoshan Zhang, Peter D. Kwong, John R. Mascola, C. Theo Verrips, Nika M. Strokappe, Lucy Rutten, Laura E. McCoy, Robin A. Weiss, Corrine S. Brown, Raven Jackson, Guido Silvestri, Mark Connors, Dennis R. Burton, George M. Shaw, Michel C. Nussenzweig, Pamela J. Bjorkman, David D. Ho, Michael Farzan, Beatrice H. Hahn
Publikováno v:
mBio, Vol 6, Iss 2 (2015)
ABSTRACT Broadly cross-reactive neutralizing antibodies (bNabs) represent powerful tools to combat human immunodeficiency virus type 1 (HIV-1) infection. Here, we examined whether HIV-1-specific bNabs are capable of cross-neutralizing distantly relat
Externí odkaz:
https://doaj.org/article/46821e94c4f84dc3b70247c0404d431a
Autor:
Simon M Langer, Kristina Hopfensperger, Shilpa S Iyer, Edward F Kreider, Gerald H Learn, Lan-Hui Lee, Beatrice H Hahn, Daniel Sauter
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142118 (2015)
Pandemic strains of HIV-1 (group M) encode a total of nine structural (gag, pol, env), regulatory (rev, tat) and accessory (vif, vpr, vpu, nef) genes. However, some subtype A and C viruses exhibit an unusual gene arrangement in which the first exon o
Externí odkaz:
https://doaj.org/article/bd6fd915bde746e5b7c54eed99ba91db
Autor:
Hongshuo Song, Bhavna Hora, Tanmoy Bhattacharya, Nilu Goonetilleke, Michael K P Liu, Kevin Wiehe, Hui Li, Shilpa S Iyer, Andrew J McMichael, Alan S Perelson, Feng Gao
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102734 (2014)
Immune escape mutations that revert back to the consensus sequence frequently occur in newly HIV-1-infected individuals and have been thought to render the viruses more fit. However, their impact on viral fitness and their interaction with other immu
Externí odkaz:
https://doaj.org/article/c29a8a2f8ba94141b1400ac1d51a81bc
Autor:
Nicholas F Parrish, Craig B Wilen, Lauren B Banks, Shilpa S Iyer, Jennifer M Pfaff, Jesus F Salazar-Gonzalez, Maria G Salazar, Julie M Decker, Erica H Parrish, Anna Berg, Jennifer Hopper, Bhavna Hora, Amit Kumar, Tatenda Mahlokozera, Sally Yuan, Charl Coleman, Marion Vermeulen, Haitao Ding, Christina Ochsenbauer, John C Tilton, Sallie R Permar, John C Kappes, Michael R Betts, Michael P Busch, Feng Gao, David Montefiori, Barton F Haynes, George M Shaw, Beatrice H Hahn, Robert W Doms
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002686 (2012)
Sexual transmission of human immunodeficiency virus type 1 (HIV-1) most often results from productive infection by a single transmitted/founder (T/F) virus, indicating a stringent mucosal bottleneck. Understanding the viral traits that overcome this
Externí odkaz:
https://doaj.org/article/30936a9dc7f44f478975974860e15f41
Autor:
Katharine J Bar, Chun-yen Tsao, Shilpa S Iyer, Julie M Decker, Yongping Yang, Mattia Bonsignori, Xi Chen, Kwan-Ki Hwang, David C Montefiori, Hua-Xin Liao, Peter Hraber, William Fischer, Hui Li, Shuyi Wang, Sarah Sterrett, Brandon F Keele, Vitaly V Ganusov, Alan S Perelson, Bette T Korber, Ivelin Georgiev, Jason S McLellan, Jeffrey W Pavlicek, Feng Gao, Barton F Haynes, Beatrice H Hahn, Peter D Kwong, George M Shaw
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002721 (2012)
Single genome sequencing of early HIV-1 genomes provides a sensitive, dynamic assessment of virus evolution and insight into the earliest anti-viral immune responses in vivo. By using this approach, together with deep sequencing, site-directed mutage
Externí odkaz:
https://doaj.org/article/3b0dc36fc26244f580f06b3696c32358
Autor:
Ronnie M. Russell, Shilpa S. Iyer, Timothy Decker, Persephone Borrow, Gerald H. Learn, Marcos V. P. Gondim, Lindsey J. Plenderleith, Hannah J. Barbian, Yingying Li, Paul M. Sharp, Scott Sherrill-Mix, Beatrice H. Hahn, Christiana M. Shaw, Frederic Bibollet-Ruche, Barton F. Haynes, George M. Shaw, Catherine Y. Bahari, Andrew G. Smith
Publikováno v:
Iyer, S S, Bibollet-Ruche, F, Sherrill-Mix, S, Learn, G H, Plenderleith, L J, Smith, A G, Barbian, H J, Russell, R M, Gondim, M V, Bahari, C Y, Shaw, C M, Li, Y, Decker, T, Haynes, B F, Shaw, G M, Sharp, P M, Borrow, P & Hahn, B H 2017, ' Resistance to Type 1 Interferons is a Major Determinant of HIV-1 Transmission Fitness ', Proceedings of the National Academy of Sciences, vol. 114, no. 4, pp. 590-599 . https://doi.org/10.1073/pnas.1620144114
Sexual transmission of HIV-1 is an inefficient process, with only one or few variants of the donor quasispecies establishing the new infection. A critical, and as yet unresolved, question is whether the mucosal bottleneck selects for viruses with inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa73725223d265b9f64d45f02ec43a5a
https://doi.org/10.1073/pnas.1620144114
https://doi.org/10.1073/pnas.1620144114
Autor:
Beatrice H. Hahn, Lara Zajic, Bhavna Hora, George M. Shaw, Julie M. Decker, Amit Kumar, Haitao Ding, Jennifer Hopper, Christina Ochsenbauer, Anthony P. West, Robert W. Doms, John C. Kappes, Feng Gao, Shilpa S. Iyer, Thomas N. Denny, Barton F. Haynes, Mark Muldoon, Nina Bhardwaj, Hannah J. Barbian, Hui Li, Nicholas F. Parrish, James Theiler, Fangping Cai, Erica H. Parrish, Elena E. Giorgi, Anna Berg, Persephone Borrow, Pamela J. Bjorkman, Bette T. Korber, Craig B. Wilen, Meagan O’Brien, Rachel P. Galimidi
Publikováno v:
Proceedings of the National Academy of Sciences. 110:6626-6633
Defining the virus–host interactions responsible for HIV-1 transmission, including the phenotypic requirements of viruses capable of establishing de novo infections, could be important for AIDS vaccine development. Previous analyses have failed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e08d5133b8c1182703192f2399d14c
https://doi.org/10.1073/pnas.1304288110
https://doi.org/10.1073/pnas.1304288110
Autor:
Benhur Lee, Craig B. Wilen, Fang-Hua Lee, Zahra F. Parker, Chukwuka A. Didigu, Shilpa S. Iyer, John P. Moore, Per Johan Klasse, Beatrice H. Hahn, Robert W. Doms, Kelechi Chikere, Reem Berro, George M. Shaw, Nicholas F. Parrish
Publikováno v:
Journal of Virology. 87:2401-2411
Infection by HIV-1 most often results from the successful transmission and propagation of a single virus variant, termed the transmitted/founder (T/F) virus. Here, we compared the attachment and entry properties of envelope (Env) glycoproteins from T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f506c850cca66fc3bee8d211df8d7e20
https://doi.org/10.1128/jvi.02964-12
https://doi.org/10.1128/jvi.02964-12