Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Shilpa Radia"'
Autor:
Michael A. Walker, Shilpa Radia, Dalton King, Shirley J. Lasch, David Willner, Hofstead Sandra J, Gene M. Dubowchik, Harold Mastalerz, Raymond A. Firestone, Pamela A. Trail
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:1529-1532
Bivalent doxorubicin (DOX)-dipeptides ( 16a – c ) were prepared and conjugated to the monoclonal antibody BR96. The dipeptides are cleaved by lysosomal proteases following internalization of the resulting immunoconjugates. Conjugate 18b demonstrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::933401d420d7b01374ef7d812e2fa84b
https://doi.org/10.1016/s0960-894x(02)00194-4
https://doi.org/10.1016/s0960-894x(02)00194-4
Autor:
Gene M. Dubowchik, Shilpa Radia
Publikováno v:
Tetrahedron Letters. 38:5257-5260
Cathepsin B-sensitive maleimidocaproyl-Phe-Lys linker compounds containing acid-sensitive anticancer drugs doxorubicin, mitomycin C and paclitaxel (taxol®) attached through a self-immolative p-aminobenzylcarbonyl spacer were prepared using monometho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ad8292090a96acd0ec814eebd6d0d47
https://doi.org/10.1016/s0040-4039(97)01158-1
https://doi.org/10.1016/s0040-4039(97)01158-1
Autor:
Shilpa Radia, Gene M. Dubowchik
Publikováno v:
ChemInform. 28
Cathepsin B-sensitive maleimidocaproyl-Phe-Lys linker compounds containing acid-sensitive anticancer drugs doxorubicin, mitomycin C and paclitaxel (taxol®) attached through a self-immolative p-aminobenzylcarbonyl spacer were prepared using monometho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43fbf3819a03db42c4666ba005fcee14
https://doi.org/10.1002/chin.199745286
https://doi.org/10.1002/chin.199745286