Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Shile Huang"'
Publikováno v:
Cells, Vol 13, Iss 21, p 1752 (2024)
Lung cancer is a leading cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) is the most prevalent lung cancer subtype. Ciclopirox olamine (CPX), an off-patent fungicide, has been identified as a new anticancer agent. Prexase
Externí odkaz:
https://doaj.org/article/d6a3ddc03c9748eea75f619d82d1ac04
Publikováno v:
Cells, Vol 13, Iss 17, p 1500 (2024)
Transduction of molecular signaling is a fundamental mechanism that allows a living cell to communicate internally with other cells and its environment through chemical or physical signals, thereby maintaining its structural integrity and triggering
Externí odkaz:
https://doaj.org/article/5551386fee6a4b5f89c2a8e2c85f1dba
Autor:
Biao Chen, Guijie Guo, Guoqing Wang, Qianwen Zhu, Lulu Wang, Wenhao Shi, Song Wang, Yuhai Chen, Xiaojuan Chi, Faxin Wen, Mohamed Maarouf, Shile Huang, Zhou Yang, Ji-Long Chen
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011958 (2024)
Autophagy-related protein 7 (ATG7) is an essential autophagy effector enzyme. Although it is well known that autophagy plays crucial roles in the infections with various viruses including influenza A virus (IAV), function and underlying mechanism of
Externí odkaz:
https://doaj.org/article/5001d3bbd6a6484aa696146f1732c0ef
Publikováno v:
Cells, Vol 13, Iss 10, p 805 (2024)
O-linked-β-D-N-acetylglucosamine (O-GlcNAc) glycosylation (O-GlcNAcylation), which is dynamically regulated by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA), is a post-translational modification involved in multiple cellular processes. O-GlcNAcyl
Externí odkaz:
https://doaj.org/article/680350f647524e77b96b17bc055f33ba
Autor:
Hongling He, Ting Cai, Qiaozhu Chen, Zilian Chen, Boyue Zhang, Changyi Chen, Yueze Wang, Yan Liu, Yueming Wang, Yongwen Luo, Shile Huang, Jun Luo, Xiaofeng Guo
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4616 (2024)
Tripartite motif (TRIM) proteins are a multifunctional E3 ubiquitin ligase family that participates in various cellular processes. Recent studies have shown that TRIM proteins play important roles in regulating host–virus interactions through speci
Externí odkaz:
https://doaj.org/article/83460d1e91424f17bb1086a3601c421d
Autor:
Terry C. Lairmore, Jehan Abdulsattar, Arrigo De Benedetti, Runhua Shi, Shile Huang, Md Imtiaz Khalil, Stephan N. Witt
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-7 (2023)
Abstract Background MEN1, which codes for the protein menin, is a tumor suppressor in neuroendocrine tissue. In cholangiocarcinoma (CCA) cell lines the overexpression of menin decreased proliferation, angiogenesis, migration, and invasion in vitro an
Externí odkaz:
https://doaj.org/article/274d4b51de0545169d190e224abda9a9
Autor:
Shasha Liu, Siya Liu, Ziding Yu, Wenzhuo Zhou, Meichun Zheng, Rongrong Gu, Jinxuan Hong, Zhou Yang, Xiaojuan Chi, Guijie Guo, Xinxin Li, Na Chen, Shile Huang, Song Wang, Ji-Long Chen
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112806- (2023)
Summary: This study identifies interleukin-6 (IL-6)-independent phosphorylation of STAT3 Y705 at the early stage of infection with several viruses, including influenza A virus (IAV). Such activation of STAT3 is dependent on the retinoic acid-induced
Externí odkaz:
https://doaj.org/article/aaa3f4df32624c9286f4fd3d2926bd8f
Publikováno v:
Cells, Vol 13, Iss 2, p 183 (2024)
Rabies virus (RABV) is a single-stranded negative-sense RNA virus belonging to the Rhabdoviridae family and Lyssavirus genus, which is highly neurotropic and can infect almost all warm-blooded animals, including humans. Autophagy and apoptosis are tw
Externí odkaz:
https://doaj.org/article/a54d55461c3549d7b6452c9dfeb0fe0c
Autor:
Tithi Roy, Sergette Banang-Mbeumi, Samuel T. Boateng, Emmanuelle M. Ruiz, Roxane-Cherille N. Chamcheu, Lin Kang, Judy A. King, Anthony L. Walker, Bolni Marius Nagalo, Konstantin G. Kousoulas, Stephane Esnault, Shile Huang, Jean Christopher Chamcheu
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Psoriasis is a chronic autoimmune inflammatory skin disorder characterized by epidermal hyperplasia and aberrant immune response. In addition to aberrant cytokine production, psoriasis is associated with activation of the Akt/mTOR pathway. mTOR/S6K1
Externí odkaz:
https://doaj.org/article/aac2a82940c348b5a3ec4d64743b35a6
Autor:
Kul Raj Rai, Yuan Liao, Mengjuan Cai, Haori Qiu, Faxin Wen, Min Peng, Song Wang, Shasha Liu, Guijie Guo, Xiaojuan Chi, Mohamed Maarouf, Yuhai Chen, Shile Huang, Ji-Long Chen
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT MIR155HG encodes a precursor RNA of microRNA-155 (miRNA-155). We previously identified this RNA also as a long noncoding RNA (lncRNA) that we call lncRNA-155. To define the functions of miRNA-155 and lncRNA-155, we generated miRNA-155 knocko
Externí odkaz:
https://doaj.org/article/bd73415236794d19bc0e1e08983be969