Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shila Patel"'
Publikováno v:
Journal of Agricultural and Food Chemistry. 57:9393-9399
Monoclonal antibodies were raised to haptens containing moieties common to both the triazole fungicide penconazole and its proposed primary urinary metabolite (4-(2,4-dichlorophenyl)-5-(H-1,2,4-triazol-1-yl)pentoic acid). The monoclonal antibody 2E4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba86a5cef002df3211b613b3d8bd23f0
https://doi.org/10.1021/jf9031469
https://doi.org/10.1021/jf9031469
Publikováno v:
International Journal of Peptide and Protein Research. 46:79-87
A peptide mixture containing 21 peptide sequences has been constructed to test the Bowman-Birk inhibitor reactive-site loop motif as the basis of inhibition for a range of serine proteases. The 21 peptides are all based on an 11 amino acid sequence d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759c07fb6b4de3826a1e6ce07ea784d9
https://doi.org/10.1111/j.1399-3011.1995.tb00585.x
https://doi.org/10.1111/j.1399-3011.1995.tb00585.x
Autor:
Paul Bamborough, Ian Robert Baldwin, Jo Quinn, Don O. Somers, Christopher J. Mooney, Claudine Haslam, Shila Patel, Suchete S. Hunjan, Tim Longstaff
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:5285-5289
New kinase inhibitors can be found by synthesis of targeted arrays of compounds designed using system-based knowledge as well as through screening focused or diverse compounds. Most array strategies aim to add functionality to a fragment that binds i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75aa9e854c0856f8835b81406f135caa
https://doi.org/10.1016/j.bmcl.2008.08.051
https://doi.org/10.1016/j.bmcl.2008.08.051
Autor:
Ben C. Maddison, Angus I. Best, Garry C. Whitelam, Martin J. Woodward, Roberto M. La Ragione, Shila Patel, Kevin C. Gough
Publikováno v:
Microbes and Infection. 8:426-433
Intimin and EspA proteins are virulence factors expressed by attaching and effacing Escherichia coli (AEEC) such as enteropathogenic and enterohaemorrhagic E. coli. The EspA protein makes up a filament structure forming part of the type III secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09f1ffd00bdea9a6738c40dca717d401
https://doi.org/10.1016/j.micinf.2005.07.009
https://doi.org/10.1016/j.micinf.2005.07.009
Publikováno v:
Journal of Biological Chemistry. 276:6234-6242
C-H bond breakage by tryptophan tryptophylquinone (TTQ)-dependent methylamine dehydrogenase (MADH) occurs by vibrationally assisted tunneling (Basran, J., Sutcliffe, M. J., and Scrutton, N. S. (1999) Biochemistry 38, 3218--3222). We show here a simil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9578705f1f3758efcc418ff7beef6ba5
https://doi.org/10.1074/jbc.m008141200
https://doi.org/10.1074/jbc.m008141200
Autor:
Christopher W. Wharton, ‡ Chi-Man Tang, Anne Cleasby, Shila Patel, Malcolm Ward, Harren Jhoti, Callum J. Campbell, Malcolm P. Weir, Clive J. Dix, Christopher J. Mooney, and Alan J. Wonacott, Richard J. Dennis, Susanne S. Bethell, Harry Finch
Publikováno v:
Biochemistry. 37:6645-6657
High-throughput screening of methanolic extracts from the leaves of the plant Lantana camara identified potent inhibitors of human alpha-thrombin, which were shown to be 5,5-trans-fused cyclic lactone euphane triterpenes [O'Neill et al. (1998) J. Nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd0725d1c7ec79046f39856bc9ee189
https://doi.org/10.1021/bi972499o
https://doi.org/10.1021/bi972499o
Autor:
Duncan S. Holmes, Ann Louise Walker, Katherine Louise Jones, Chris D. Edwards, Dramane I. Laine, Don O. Somers, Paul Bamborough, Smith Kathryn Jane, Shila Patel, Jacky B. Buckton, Suzanne J. deBoeck, Richard Martyn Angell, Penny A. Smee, Nicola Mary Aston, Stuart G. Cockerill
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(15)
The biphenyl amides (BPAs) are a novel series of p38alpha MAP kinase inhibitor. The optimisation of the series to give compounds that are potent in an in vivo disease model is discussed. SAR is presented and rationalised with reference to the crystal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c96035dc37dc9d60b0821a85dd7535ae
https://pubmed.ncbi.nlm.nih.gov/18614366
https://pubmed.ncbi.nlm.nih.gov/18614366
Autor:
Shila, Patel
Publikováno v:
Nursing times. 103(10)
Shila Patel explains the different management protocols for controlling an outbreak of MRSA in hospital and the community.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b09d905c0824d9d35f397a658e52e5e
https://pubmed.ncbi.nlm.nih.gov/17388152
https://pubmed.ncbi.nlm.nih.gov/17388152
Autor:
Shila, Patel
Publikováno v:
Nursing times. 102(24)
Shila Patel explains the principles of glove use, highlighting the procedures for which they are indicated and advising on appropriate storage.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e121468372a55bb52156fd67b78380dd
https://pubmed.ncbi.nlm.nih.gov/16827049
https://pubmed.ncbi.nlm.nih.gov/16827049
Autor:
Ben C. Maddison, M. Baier, Roger F.L. James, B. Oidtmann, Kevin C. Gough, Garry C. Whitelam, H.E. Conlon, Shila Patel
Publikováno v:
Journal of immunological methods. 306(1-2)
We report the production and characterisation of three monoclonal antibodies to the prion protein (PrP) of Rainbow trout (Oncorhynchus mykiss), a piscine protein with characteristic structural features common to mammalian prion protein. All of the an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b361a00f17a1435baa4eaebd2f8f06f
https://pubmed.ncbi.nlm.nih.gov/16225888
https://pubmed.ncbi.nlm.nih.gov/16225888