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Minor prion substrains overcome transmission barriers.

Autor: Steadman BS; Department of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA., Bian J; Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture - Agricultural Research Services, Ames, Iowa, USA., Shikiya RA; Department of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA., Bartz JC; Department of Medical Microbiology and Immunology, School of Medicine, Creighton University, Omaha, Nebraska, USA.

Publikováno v: MBio [mBio] 2024 Nov 13; Vol. 15 (11), pp. e0272124. Date of Electronic Publication: 2024 Oct 23.

Efficient interspecies transmission of synthetic prions.

Autor: Block AJ; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America., Shikiya RA; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America., Eckland TE; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America., Kincaid AE; Department of Pharmacy Science, Creighton University, Omaha, Nebraska, United States of America., Walters RW; Department of Medicine, Creighton University, Omaha, Nebraska, United States of America., Ma J; Van Andel Institute, Center for Neurodegenerative Science, Grand Rapids, Michigan, United States of America., Bartz JC; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2021 Jul 14; Vol. 17 (7), pp. e1009765. Date of Electronic Publication: 2021 Jul 14 (Print Publication: 2021).

Engineering a murine cell line for the stable propagation of hamster prions.

Autor: Bourkas MEC; From the Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada M5T 0S8.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada M5T 0S8., Arshad H; From the Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada M5T 0S8.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada M5T 0S8., Al-Azzawi ZAM; From the Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada M5T 0S8.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada M5T 0S8., Halgas O; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada M5T 0S8., Shikiya RA; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, 68178., Mehrabian M; From the Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada M5T 0S8.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5T 0S8, and., Schmitt-Ulms G; From the Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada M5T 0S8.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada M5T 0S8, and., Bartz JC; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, 68178., Watts JC; From the Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada M5T 0S8, joel.watts@utoronto.ca.; Department of Biochemistry, University of Toronto, Toronto, Ontario, Canada M5T 0S8.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2019 Mar 29; Vol. 294 (13), pp. 4911-4923. Date of Electronic Publication: 2019 Jan 31.

PrPSc formation and clearance as determinants of prion tropism.

Autor: Shikiya RA; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America., Langenfeld KA; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America., Eckland TE; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America., Trinh J; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America., Holec SAM; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America., Mathiason CK; Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America., Kincaid AE; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America.; Department of Pharmacy Science, Creighton University, Omaha, Nebraska, United States of America., Bartz JC; Department of Medical Microbiology and Immunology, Creighton University, Omaha, Nebraska, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2017 Mar 29; Vol. 13 (3), pp. e1006298. Date of Electronic Publication: 2017 Mar 29 (Print Publication: 2017).