Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shikha Tarang"'
Autor:
Michael D. Weston, Shikha Tarang, Marsha L. Pierce, Umesh Pyakurel, Sonia M. Rocha-Sanchez, JoAnn McGee, Edward J. Walsh, Garrett A. Soukup
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Abstract Germline mutations in Mir96, one of three co-expressed polycistronic miRNA genes (Mir96, Mir182, Mir183), cause hereditary hearing loss in humans and mice. Transgenic FVB/NCrl- Tg(GFAP-Mir183,Mir96,Mir182)MDW1 mice (Tg1MDW), which overexpres
Externí odkaz:
https://doaj.org/article/b6b53b4fce0240b49d5686f535f22611
Autor:
Sonia M. Rocha-Sanchez, Shikha Tarang, Michael D. Weston, Varun Kesherwani, Blake LaTendresse, Laramie Lindgren
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-7 (2020)
Scientific Reports
Scientific Reports
Invasive candidiasis (IC) is the most common nosocomial infection and a leading cause of mycoses-related deaths. High-systemic toxicity and emergence of antifungal-resistant species warrant the development of newer preventive approaches against IC. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d23660bd3b66e09ad36bc05f167123b
http://link.springer.com/article/10.1038/s41598-020-57906-x
http://link.springer.com/article/10.1038/s41598-020-57906-x
Autor:
Shikha Tarang
Publikováno v:
American Journal of Biomedical Science & Research. 7:451-453
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::043a6eae5372c770a4590569d25abced
https://doi.org/10.34297/ajbsr.2020.07.001196
https://doi.org/10.34297/ajbsr.2020.07.001196
Autor:
Shikha Tarang, Varun Kesherwani
Publikováno v:
Vaccine. 37:3457-3463
In kidney transplant recipients (KTRs) long-term immunosuppression leads to BK virus (BKV) reactivation, with an increased incidence of BKV-associated pathologies and allograft rejection. The current approaches to limit BKV infection include a reduct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb5f7c82977360bb1ba290889ce89d0
https://doi.org/10.1016/j.vaccine.2019.04.096
https://doi.org/10.1016/j.vaccine.2019.04.096
Autor:
Shikha Tarang, Kay Uwe Wagner, Michael D. Weston, Umesh Pyakurel, Sonia M. Rocha-Sanchez, Timothy A. Jones, Sarath Vijayakumar
Publikováno v:
Hear Res
The retinoblastoma family of pocket proteins (pRBs), composed of Rb1, p107, and p130 are negative regulators of cell-cycle progression. The deletion of any individual pRB in the auditory system triggers hair cells' (HCs) and supporting cells' (SCs) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8406ad7dcaae314b1ba522f0b2051164
https://europepmc.org/articles/PMC7204889/
https://europepmc.org/articles/PMC7204889/
Publikováno v:
Journal of visualized experiments : JoVE. (143)
Dominant-negative (DN) protein inhibition is a powerful method to manipulate protein function and offers several advantages over other genome-based approaches. For example, although chimeric and Cre-LoxP targeting strategies have been widely used, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420842549fd96a49a05f0e33482a44ae
https://pubmed.ncbi.nlm.nih.gov/30663696
https://pubmed.ncbi.nlm.nih.gov/30663696
Autor:
Huizhan Liu, Shikha Tarang, Linda Goodman, Olivia Fuson, Sonia M. Rocha-Sanchez, Marisa Zallocchi, David Z.Z. He, Umesh Pyakurel
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Hair cell (HC) death is the leading cause of hearing and balance disorders in humans. It can be triggered by multiple insults, including noise, aging, and treatment with certain therapeutic drugs. As society becomes more technologically advanced, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ab4a02a120df84e071c6bd91891282
https://doi.org/10.1038/s41598-018-33520-w
https://doi.org/10.1038/s41598-018-33520-w
Autor:
Umesh Pyakurel, Garrett A. Soukup, JoAnn McGee, Marsha L. Pierce, Shikha Tarang, Michael D. Weston, Edward J. Walsh, Sonia M. Rocha-Sanchez
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-19 (2018)
Germline mutations in Mir96, one of three co-expressed polycistronic miRNA genes (Mir96, Mir182, Mir183), cause hereditary hearing loss in humans and mice. Transgenic FVB/NCrl- Tg(GFAP-Mir183,Mir96,Mir182)MDW1 mice (Tg1MDW), which overexpress this ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774b19652ce9cd9cce1f25d514e8ff70
http://europepmc.org/articles/PMC5824881
http://europepmc.org/articles/PMC5824881
Publikováno v:
Neuroscience Letters. 576:45-50
Fasudil (HA-1077), a specific Rho kinase II (ROCKII) inhibitor, is in clinical trials for recovery from spinal cord injury (SCI). The primary role of Fasudil is in axonal regeneration, as it inhibits ROCKII, the key signaling molecule involved in col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202630bb57a3895a799ad4ddfa6d8a0e
https://doi.org/10.1016/j.neulet.2014.05.053
https://doi.org/10.1016/j.neulet.2014.05.053
Autor:
Michael D. Weston, Shikha Tarang
Publikováno v:
RNA Biology
MicroRNAs (miRNAs) are short RNA molecules that modulate post-transcriptional gene expression by partial or incomplete base-pairing to the complementary sequences on their target genes. Sequence-based miRNA target gene recognition enables the utiliza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feaca33565d558c0a5e67c05ded0591b
https://doi.org/10.4161/rna.28649
https://doi.org/10.4161/rna.28649