Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shikha Khatri"'
Autor:
Tae Hoon Kim, Jung-Yoon Yoo, Zhong Wang, John P Lydon, Shikha Khatri, Shannon M Hawkins, Richard E Leach, Asgerally T Fazleabas, Steven L Young, Bruce A Lessey, Bon Jeong Ku, Jae-Wook Jeong
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005537 (2015)
AT-rich interactive domain 1A gene (ARID1A) loss is a frequent event in endometriosis-associated ovarian carcinomas. Endometriosis is a disease in which tissue that normally grows inside the uterus grows outside the uterus, and 50% of women with endo
Externí odkaz:
https://doaj.org/article/7b5adaf9c8a143f5b95b44b41b190596
Publikováno v:
Biology of Reproduction. 94
Women with endometriosis can suffer from decreased fecundity or complete infertility via abnormal oocyte function or impaired placental-uterine interactions required for normal pregnancy establishment and maintenance. Although AT-rich interactive dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40de743d6712453ac361ad516a8e95b
https://doi.org/10.1095/biolreprod.115.133637
https://doi.org/10.1095/biolreprod.115.133637
Autor:
Asgerally T. Fazleabas, Shannon M. Hawkins, Richard Leach, Zhong Wang, Jung-Yoon Yoo, John P. Lydon, Jae Wook Jeong, Bon Jeong Ku, Shikha Khatri, Tae Hoon Kim, Steven L. Young, Bruce A. Lessey
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005537 (2015)
PLoS Genetics
PLoS Genetics
AT-rich interactive domain 1A gene (ARID1A) loss is a frequent event in endometriosis-associated ovarian carcinomas. Endometriosis is a disease in which tissue that normally grows inside the uterus grows outside the uterus, and 50% of women with endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1cc44874ef02e7da4ceb1900d16f8ac
Autor:
Uwe Fass, Raymond F. Gesteland, Michael T. Howard, John F. Atkins, Christine B. Anderson, Kevin M. Flanigan, Shikha Khatri
Publikováno v:
Annals of Neurology. 55:422-426
We report the translational readthrough levels induced by the aminoglycosides gentamicin, amikacin, tobramycin, and paromomycin for eight premature stop codon mutations identified in Duchenne's and Becker's muscular dystrophy patients. In a transient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b6d6fbb8036d5c771debc4dbcdc3cb
https://doi.org/10.1002/ana.20052
https://doi.org/10.1002/ana.20052
Autor:
David R. Plas, Jennifer F. Barger, Hasmik Yepiskoposyan, Preeti Tandon, Shikha Khatri, Catherine A. Gallo
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(6)
Pten inactivation promotes cell survival in leukemia cells by activating glycolytic metabolism. We found that targeting ribosomal protein S6 kinase 1 (S6K1) in Pten-deficient cells suppressed glycolysis and induced apoptosis. S6K1 knockdown decreased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7658c5c94d0b7ca49c53f59558e98d7c
https://pubmed.ncbi.nlm.nih.gov/21262837
https://pubmed.ncbi.nlm.nih.gov/21262837
Akt signal transduction induces coordinated increases in glycolysis and apoptosis resistance in a broad spectrum of cancers. Downstream of Akt, the FoxO transcription factors regulate apoptosis via Bim, but the contributions of FoxOs in regulating Ak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5da253b3f74cd7edbde9ac0759a9df1
https://europepmc.org/articles/PMC2871464/
https://europepmc.org/articles/PMC2871464/
Autor:
Shikha Khatri, David R. Plas
Publikováno v:
Cancer biologytherapy. 8(17)
Pathways that mediate oncogene-induced alterations in cellular metabolism are emerging as attractive new targets for enhancing apoptotic responses to cancer chemotherapeutics. Cancer cells frequently reprogram cellular metabolism in parallel with act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d68575e7dd298c64d3f875d1d8398f4
https://pubmed.ncbi.nlm.nih.gov/19597348
https://pubmed.ncbi.nlm.nih.gov/19597348
Autor:
Gaurav Aggarwal, Michael T. Howard, Shikha Khatri, John F. Atkins, Christine B. Anderson, Kevin M. Flanigan
Incorporation of the 21st amino acid, selenocysteine, into proteins is specified in all three domains of life by dynamic translational redefinition of UGA codons. In eukarya and archaea, selenocysteine insertion requires a cis-acting selenocysteine i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c32c7d64644ca45b0c48789f9b466f0
https://europepmc.org/articles/PMC1142574/
https://europepmc.org/articles/PMC1142574/
Autor:
Shikha Khatri
Publikováno v:
Biology of Reproduction. 87:541-541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c58708bb598e9af6b5f8fc07e3a195c5
https://doi.org/10.1093/biolreprod/87.s1.541
https://doi.org/10.1093/biolreprod/87.s1.541
Publikováno v:
Cancer Research. 71:LB-256
Pten loss and subsequent Akt activation promotes cell survival in human cancer cells through activation of glycolytic metabolism and repression of pro-apoptotic factors. Because sustained glycolysis is required for Akt dependent apoptosis resistance,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80912cd64e3a41c8ca03dc7919f6f485
https://doi.org/10.1158/1538-7445.am2011-lb-256
https://doi.org/10.1158/1538-7445.am2011-lb-256