Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Shike Wang"'
Autor:
Xiaochao Tan, Guan-Yu Xiao, Shike Wang, Lei Shi, Yanbin Zhao, Xin Liu, Jiang Yu, William K. Russell, Chad J. Creighton, Jonathan M. Kurie
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Hypersecretory malignant cells underlie therapeutic resistance, metastasis, and poor clinical outcomes. However, the molecular basis for malignant hypersecretion remains obscure. Here, we showed that epithelial-mesenchymal transition (EMT) initiates
Externí odkaz:
https://doaj.org/article/bf7521c5ce53496a9c18099d6e3fb8f7
Publikováno v:
BMC Bioinformatics, Vol 22, Iss S6, Pp 1-17 (2021)
Abstract Background Recent advances in simultaneous measurement of RNA and protein abundances at single-cell level provide a unique opportunity to predict protein abundance from scRNA-seq data using machine learning models. However, existing machine
Externí odkaz:
https://doaj.org/article/9955a19e0e364924a7afa745ab2e6331
Publikováno v:
Chinese Journal of Mechanical Engineering, Vol 33, Iss 1, Pp 1-10 (2020)
Abstract In gear transmission, temperature rise has a non-negligible impact on the accuracy, noise and transmission efficiency. However, there is no relevant research on the temperature rise of the anti-backlash single-roller enveloping hourglass wor
Externí odkaz:
https://doaj.org/article/325d22d00fda434d98b7396caaff84ad
Autor:
Xingqiao DENG, Shisong WANG, Shike WANG, Jie WANG, Yucheng LIU, Yangqing DOU, Ge HE, Linmao QIAN
Publikováno v:
Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 14, Iss 4, Pp JAMDSM0054-JAMDSM0054 (2020)
In this study, the moving particle semi-implicit (MPS) method is employed for numerical simulation of flow field in gearbox of high-speed railway trains so as to understand the lubrication mechanism and mode in the gearbox during high-speed operation
Externí odkaz:
https://doaj.org/article/24e8426d6768451ca26c40258595be30
Publikováno v:
Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 13, Iss 3, Pp JAMDSM0064-JAMDSM0064 (2019)
The new precision transmission system-Anti-backlash roller enveloping hourglass worm gears are now widely employed in many industrial sectors such as robot joint design, packaging production line, and CNC (computer numerical control) machine tools. T
Externí odkaz:
https://doaj.org/article/628d4fc956bc4145a58aba866e3e9426
Autor:
Shike Wang, Kuo-Hao Lee, Nathalia Victoria Araujo, Chang-Guo Zhan, Vivek M. Rangnekar, Ren Xu
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6613 (2020)
Collagen prolyl 4-hydroxylase 1 (C-P4H1) is an α-ketoglutarate (α-KG)-dependent dioxygenase that catalyzes 4-hydroxylation of proline on collagen. C-P4H1-induced prolyl hydroxylation is required for proper collagen deposition and cancer metastasis.
Externí odkaz:
https://doaj.org/article/26e2f6401a7642f491b445abc407370a
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 4, p 1246 (2018)
Cancer patients experience a four-fold increase in thrombosis risk, indicating that cancer development and progression are associated with platelet activation. Xenograft experiments and transgenic mouse models further demonstrate that platelet activa
Externí odkaz:
https://doaj.org/article/c7103e346a024572b7340e6d92c6a9bb
Autor:
Xiaochao Tan1, Shike Wang1, Guan-Yu Xiao1, Chao Wu1, Xin Liu1, Biyao Zhou1, Yu Jiang1, Duose, Dzifa Y.2, Yuanxin Xi3, Jing Wang3, Gupta, Kunika4, Pataer, Apar5, Roth, Jack A.5, Kim, Michael P.6, Fengju Chen7, Creighton, Chad J.7, Russell, William K.8, Kurie, Jonathan M.1
Publikováno v:
Journal of Clinical Investigation. 6/17/2024, Vol. 134 Issue 12, p1-17. 17p.
Publikováno v:
IEEE Transactions on Power Electronics. 38:6597-6612
Publikováno v:
Bioinformatics. 38:ii13-ii19
Motivation Detecting synthetic lethality (SL) is a promising strategy for identifying anti-cancer drug targets. Targeting SL partners of a primary gene mutated in cancer is selectively lethal to cancer cells. Due to high cost of wet-lab experiments a