Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Shikai Geng"'
Autor:
Li Chen, Wanzun Lin, Haojiong Zhang, Shikai Geng, Ziyu Le, Fangzhu Wan, Qingting Huang, Huaiyuan Chen, Xingyu Liu, Jiade J. Lu, Lin Kong
Publikováno v:
Cell Death and Disease, Vol 15, Iss 3, Pp 1-15 (2024)
Abstract Tribbles pseudokinase 3 (TRIB3) has been identified recently as a novel oncogene in several cancers. Still, further extensive research is imperative to elucidate its function and the molecular mechanisms underlying its involvement in the pro
Externí odkaz:
https://doaj.org/article/fd7ea6fe581c42ddb8e2d1dbd50e0f77
Autor:
Wanzun Lin, Li Chen, Haojiong Zhang, Xianxin Qiu, Qingting Huang, Fangzhu Wan, Ziyu Le, Shikai Geng, Anlan Zhang, Sufang Qiu, Long Chen, Lin Kong, Jiade J. Lu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
YTHDF1 is an m6A reader that binds to methylated RNA and facilitates translation. Here the authors show that tumor intrinsic YTHDF1 promotes tumorigenesis by regulating lysosomal proteolysis of MHC-I and that YTHDF1 targeting boosts anti-tumor immuni
Externí odkaz:
https://doaj.org/article/4b73dcf1c1ca49ba94758647df26f8a5
Autor:
Fangfang Sun, Wanlong Wu, Shuang Ye, Nan Shen, Yi Chen, Shikai Geng, Haiting Wang, Liling Zhao, Danting Zhang, Yuhong Zhou, Liqin Yu
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Objective To evaluate the risk of major infections and the relationship between major infections and mortality in patients with newly diagnosed SLE.Methods A newly diagnosed (10, peripheral lymphocyte count 104 µmol/L was established to identify pat
Externí odkaz:
https://doaj.org/article/4b63f0c65f364747affb8b8cbb8b0fc2
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Vasculogenic mimicry (VM) is a kind of tumor vasculature providing blood supply for tumor growth, and the formation of VM is independent of vascular endothelial cells. Instead, VM structures are formed by differentiated tumor cells such as nasopharyn
Externí odkaz:
https://doaj.org/article/05482fa9cfb14ba78f64391e32f883a4
Autor:
Le Zhang, Wei Luan, Shikai Geng, Shuang Ye, Xiaodong Wang, Liping Qian, Yang Ding, Ting Li, Anli Jiang
Publikováno v:
BMC Health Services Research, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background To explore the inadequacies of health service and its impact on clinical outcomes of patients with systemic lupus erythematosus (SLE) in China. Methods A total of 210 SLE patients were randomly recruited between January 2017 and J
Externí odkaz:
https://doaj.org/article/497ed0e47852476ba1e8e167eeadb93e
Autor:
Ting Li, Fangfang Sun, Xiaodong Wang, Shuang Ye, Zhe Liu, Shikai Geng, Haiting Wang, Huijing Wang, Weiguo Wan, Liangjing Lu, Xiangyu Teng, Laurence Morel
Publikováno v:
Lupus Science and Medicine, Vol 7, Iss 1 (2020)
Objective To confirm that metformin prevents flares in patients with SLE with low disease activity, we performed a post hoc analysis combining our previous two randomised trials.Methods Post hoc analyses were performed on data from the open-labelled
Externí odkaz:
https://doaj.org/article/9390b412c58f4ba88d42790ee6eeb26e
Autor:
Fangfang Chen, Yitian Lang, Shikai Geng, Xiaodong Wang, Liangjing Lu, Shuang Ye, Le Zhang, Ting Li
Background: The therapy of rheumatoid arthritis (RA) was advanced by biological agents, yet costly. This study aims to identify the effective threshold dose of etanercept (ENT) biosimilars and evaluate the efficacy, safety and cost-effectiveness in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a470ab2649152a7241434bcfed275b0
https://doi.org/10.21203/rs.3.rs-1933280/v1
https://doi.org/10.21203/rs.3.rs-1933280/v1
Autor:
Haiting Wang, Yuhong Zhou, Liqin Yu, Wanlong Wu, Liling Zhao, Shikai Geng, Fangfang Sun, Danting Zhang, Nan Shen, Yi Chen, Shuang Ye
Publikováno v:
Lupus sciencemedicine. 9(1)
ObjectiveTo evaluate the risk of major infections and the relationship between major infections and mortality in patients with newly diagnosed SLE.MethodsA newly diagnosed (ResultsAmong the 494 patients enrolled in the hSLIC cohort, there were 69 doc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a247110338c7444c98940523d123b5
https://pubmed.ncbi.nlm.nih.gov/36041813
https://pubmed.ncbi.nlm.nih.gov/36041813
Autor:
Wenwen Xu, Jie Chen, Fangfang Sun, Shuhui Sun, Liyang Gu, Wanlong Wu, Zhiwei Chen, Xiaodong Wang, Shikai Geng, Ting Li, Shuang Ye
Publikováno v:
Clinical Rheumatology. 39:3099-3104
Immune thrombocytopenia (ITP) is a common complication of connective tissue diseases (CTD). However, refractory and recurrent cases are frequent, who often need intensive immunotherapy. In the real world to compare the efficacy and safety of two comm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65802daf547aaed3796efef6b6f84baf
https://doi.org/10.1007/s10067-020-05152-x
https://doi.org/10.1007/s10067-020-05152-x
Autor:
Xiangyu Teng, Liangjing Lu, Zhe Liu, Ting Li, Shuang Ye, Shikai Geng, Fangfang Sun, Hai Ting Wang, Weiguo Wan, Hui Jing Wang, Laurence Morel, Xiaodong Wang
Publikováno v:
The Lancet Rheumatology. 2:e210-e216
Summary Background Immunometabolism is involved in the pathogenesis of systemic lupus erythematosus (SLE). The aim of this study was to repurpose metformin, an anti-diabetic drug that regulates systemic and cellular metabolism, and assess its effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f59cfcf2c3529d25431c71f95dc476f5
https://doi.org/10.1016/s2665-9913(20)30004-7
https://doi.org/10.1016/s2665-9913(20)30004-7