Výsledky vyhledávání - "Shijun Zhong"

Akademický článek

Analysis of typical interference and influence factors of Beijing geoelectric field observation network

Autor: Lihong Wang, Shijun Zhu, Tongli Wang, Juzhen Li, Minjie Wu, Shijun Zhong

Publikováno v: 地震科学进展, Vol 51, Iss 12, Pp 560-568 (2021)

In this paper, the abnormal event records of Beijing Geoelectric Field Observation Network (BGFON) from January 2015 to December 2020 are processed and analyzed. Based on the data tracking and analysis, it is concluded that the typical disturbances o

Externí odkaz: https://doaj.org/article/c6977187884c45b7904280da04be5aaf

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Akademický článek

Enhanced fermentative performance under stresses of multiple lignocellulose-derived inhibitors by overexpression of a typical 2-Cys peroxiredoxin from Kluyveromyces marxianus

Autor: Jiaoqi Gao, Hualiang Feng, Wenjie Yuan, Yimin Li, Shengbo Hou, Shijun Zhong, Fengwu Bai

Publikováno v: Biotechnology for Biofuels, Vol 10, Iss 1, Pp 1-13 (2017)

Abstract Background Bioethanol from lignocellulosic materials is of great significance to the production of renewable fuels due to its wide sources. However, multiple inhibitors generated from pretreatments represent great challenges for its industri

Externí odkaz: https://doaj.org/article/bd7b858467d243fa92efe44e54031207

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Akademický článek

A novel GTP-binding inhibitor, FX2149, attenuates LRRK2 toxicity in Parkinson's disease models.

Autor: Tianxia Li, Xinhua He, Joseph M Thomas, Dejun Yang, Shijun Zhong, Fengtian Xue, Wanli W Smith

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0122461 (2015)

Leucine-rich repeat kinase-2 (LRRK2), a cytoplasmic protein containing both GTP binding and kinase activities, has emerged as a highly promising drug target for Parkinson's disease (PD). The majority of PD-linked mutations in LRRK2 dysregulate its GT

Externí odkaz: https://doaj.org/article/6bed5f9704944e7abce45961d47d49c3

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Data from Rational Design of Human DNA Ligase Inhibitors that Target Cellular DNA Replication and Repair

Autor: Alan E. Tomkinson, Alexander D. MacKerell, Gerald M. Wilson, Tom Ellenberger, Barbara Dziegielewska, Xiao Zhu, Shijun Zhong, Xi Chen

Based on the crystal structure of human DNA ligase I complexed with nicked DNA, computer-aided drug design was used to identify compounds in a database of 1.5 million commercially available low molecular weight chemicals that were predicted to bind t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75cb159977d4f9c0d12d9bd73e0d4a89
https://doi.org/10.1158/0008-5472.c.6497526

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